For over three decades tissue engineering and regenerative medicine has been employed to save lives and improve the quality of life in humans and animals. Various scaffolding techniques have been developed to recreate the extracellular matrix (ECM) of different types of tissues. Some of these include freeze drying, salt leaching, 3D printing and electrospinning. Electrospinning in particular is a technique that has gained popularity among researchers and industries to create scaffolding material for tissue engineering and regenerative medicine. Electrospinning is a versatile, easy to use, cost-effective, and flexible technique for processing biocompatible and biodegradable materials. For example, it can create fibers in the nano- and micro-scale, process thermolabile bioactives, and chemically or physically modify the sample to desired needs.