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# Nanoscience Instruments

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## Posts
- [Nanoscience Instruments & Thermo Fisher Scientific Joint Microscopy & Spectroscopy Workshops](https://www.nanoscience.com/short-courses/nanoscience-instruments-thermo-fisher-scientific-joint-microscopy-spectroscopy-workshops/): Join Nanoscience Instruments and Thermo Fisher Scientific for an interactive workshop exploring how complementary microscopy and spectroscopy techniques can accelerate materials characterization and failure analysis. This hands-on event will demonstrate how the Thermo Fisher Scientific’s™ Phenom™ Desktop SEM, FTIR and Raman Microscopy Solutions work together to provide rapid morphological, elemental, and molecular information, enabling researchers and engineers to solve complex analytical challenges with greater confidence. Whether you work in materials science, semiconductors, polymers, pharmaceuticals, or advanced manufacturing, this workshop will provide practical insights into building efficient, multi-technique workflows that improve both productivity and analytical outcomes.
<div class="tces-js-style-encoded" style="display:none;">LnRiLWhlYWRpbmcuaGFzLWJhY2tncm91bmR7cGFkZGluZzowfQ==</div><script class="tces-js-style-to-head">toolsetCommonEs.styleToHead()</script>- [2026 NanoNews: SEM Edition Q2](https://www.nanoscience.com/newsletters/2026-nanonews-sem-edition-q2/): Welcome to the Scanning Electron Microscopy (SEM) edition of the Nanoscience Instruments newsletter, nanoNews! We are excited to share the latest updates, resources, and insights from the SEM community with you. In this Q2 2026 newsletter, discover new resources, upcoming training opportunities, and exciting developments across Phenom SEM technologies. If you are interested in more updates about Phenom news, we invite you to follow us on LinkedIn!
- [2026 NanoNews: Electrospinning Edition Q2](https://www.nanoscience.com/newsletters/2026-nanonews-electrospinning-edition-q2/): Welcome to the electrospinning edition of the Nanoscience Instruments newsletter, nanoNews. We are excited to share the latest updates from the community with you!    In this Spring newsletter, you will find recent webinars, white papers, and blogs that highlight the ways Fluidnatek electrospinning equipment have empowered biomedical research and development. If you are interested in more updates about electrospinning, we invite you to follow us on LinkedIn!
- [2026 NanoNews: QCM-D Edition Q2](https://www.nanoscience.com/newsletters/2026-nanonews-qcm-d-edition-q2/): Welcome to the quartz crystal microbalance with dissipation monitoring (QCM-D) edition of the Nanoscience Instruments newsletter, nanoNews. We are excited to share the latest updates from around the QCM-D community with you!  
In this Spring newsletter, you will find recent webinars and blogs that highlight use cases of QSense instruments across a variety of industries and research applications. If you are interested in more regular updates about QSense QCM-D news, we invite you to follow us on LinkedIn as well!
- [2026 NanoNews: Tensiometry Edition Q2](https://www.nanoscience.com/newsletters/2026-nanonews-tensiometry-edition-q2/): Welcome to the second quarter tensiometry edition of the Nanoscience Instruments newsletter, nanoNews. We are excited to share the latest updates from the Tensiometry community with you! This newsletter features the launch of the new Attension® Sigma Force Tensiometer line by Biolin Scientific, two on-demand webinars on wettability, interfacial tension, and biopharmaceutical formulations, plus two new blog articles on semiconductor packaging and surface free energy measurements. We&#039;re also excited to share our upcoming presence at the American Chemical Society (ACS) Fall 2026 in Chicago, IL. For the latest resources and updates, follow us on LinkedIn!
- [American Chemical Society (ACS) Fall 2026 | Aug 24 &#8211; 26, 2026 | Chicago, IL](https://www.nanoscience.com/tradeshows/american-chemical-society-acs-fall-2026-aug-24-26-2026-chicago-il/): Nanoscience Instruments provides advanced solutions for nanomaterial fabrication and characterization, helping researchers across polymer science, biomaterials, and surface chemistry advance their work. From electrospinning nanofibers to characterizing surface and interfacial properties, our technologies support a wide range of applications in materials science, biomedical research, and industrial R&amp;D.
- [Why Multiple Probe Liquids Are Essential for Accurate Surface Free Energy Measurement ](https://www.nanoscience.com/blogs/why-multiple-probe-liquids-are-essential-for-accurate-surface-free-energy-measurement/): Surface free energy (SFE) is a quantitative measure of the intermolecular forces at a solid surface. It dictates how a solid behaves when in contact with a liquid. It is an important parameter for applications relating to adhesion, bonding, adsorption, and interfacial intermolecular forces.1 Because SFE cannot be measured directly, accurately determining a material’s SFE is nontrivial. In this article, we discuss how to most accurately characterize a material’s SFE using a variety of test liquids. 
- [Nanoscience Instruments and Fastmicro Announce Partnership in North America](https://www.nanoscience.com/press-releases/nanoscience-instruments-and-fastmicro-announce-partnership-in-north-america/): Phoenix, AZ — Nanoscience Instruments is pleased to announce a strategic partnership with Fastmicro, a leading provider of automated surface particle inspection solutions. Together, the companies will deliver an integrated solution that combines rapid surface particle quantification with advanced particle characterization, helping manufacturers accelerate contamination investigations and strengthen technical cleanliness programs.
- [Microscopy &amp; Microanalysis 2026 | Aug 3-6, 2026 | Milwaukee, WI](https://www.nanoscience.com/tradeshows/microscopy-microanalysis-2026-aug-3-6-2026-milwaukee-wi/): Join us in Salt Lake City, Utah for the highlight of the microscopy calendar – M&amp;M 2025! Nanoscience Instruments is back for this annual summertime conference, and this time we’re showcasing in Booth #1925.
- [Nanoscience Instruments Expands Polymer Processing Solutions through Strategic Partnership with Fontijne Presses](https://www.nanoscience.com/press-releases/nanoscience-instruments-expands-polymer-processing-solutions-through-strategic-partnership-with-fontijne-presses/): Nanoscience Instruments is pleased to announce a new strategic partnership with Fontijne Presses, a globally recognized manufacturer of precision laboratory platen presses. Through this agreement, Nanoscience Instruments will serve as the exclusive distributor of Fontijne Presses systems in North America, expanding its portfolio of advanced materials characterization and processing solutions.
- [Evolution of the Phenom Desktop SEM ](https://www.nanoscience.com/blogs/evolution-of-the-phenom-desktop-sem/): The Phenom Scanning Electron Microscope (SEM) is turning 20 this year! In celebration of this milestone, it is worth reflecting on how the platform has evolved, from the first true benchtop SEM bridging optical and electron microscopy, to a family of systems capable of advanced surface and transmission imaging, analysis, and automation. A condensed timeline for the Phenom and Nanoscience Instruments is shown in Figure 1.
- [How Micro-compounders Enable Precise and Repeatable Color Matching in Polymers](https://www.nanoscience.com/blogs/how-micro-compounders-enable-precise-and-repeatable-color-matching-in-polymers/): Color matching in polymer compounding involves formulating and adjusting pigments, dyes, and additives to achieve a precise, repeatable target color,&nbsp;an essential requirement for ensuring product quality, brand consistency, and compliance.&nbsp;
- [Phenom Pharos STEM: Bringing True STEM Capability to the Desktop](https://www.nanoscience.com/blogs/phenom-pharos-stem-bringing-true-stem-capability-to-the-desktop/): Scanning Transmission Electron Microscopy (STEM) is a scanning-based imaging technique that uses a focused electron beam to raster scan across an ultra-thin sample, typically &lt;150 nm. Although STEM is similar to Scanning Electron Microscopy (SEM), it differs fundamentally in how electrons interact with the sample and how signals are generated (comparison shown in Table 1). Understanding these differences is critical for selecting the appropriate technique for characterization, failure analysis, or research workflows in a range of fields including materials science and life sciences.
- [2-Day SEM Short Course | Phoenix, AZ | Nov. 4 &#8211; 5, 2026](https://www.nanoscience.com/short-courses/2-day-sem-short-course-phoenix-az-november-2026/): Explore the microscopic world in our specialized 2-day Scanning Electron Microscopy (SEM) Short Course. Held in Phoenix, AZ, this immersive program is designed for both experienced practitioners and newcomers, offering an in-depth exploration of both fundamental and advanced SEM techniques. Hosted at our state-of-the-art facilities, the course features hands-on sessions with the latest Phenom Desktop SEMs, complemented by expert-led lectures. We invite you to join us for an enriching exploration that combines theoretical knowledge with hands-on experience.
- [2-Day SEM Short Course | Alexandria, VA | Sept. 2 &#8211; 3, 2026](https://www.nanoscience.com/short-courses/2-day-sem-short-course-alexandria-va-sept-2-3-2026/): Explore the microscopic world in our specialized 2-day Scanning Electron Microscopy (SEM) Short Course. Held in Alexandria, VA, this immersive program is designed for both experienced practitioners and newcomers, offering an in-depth exploration of both fundamental and advanced SEM techniques. Hosted at our state-of-the-art facilities, the course features hands-on sessions with the latest Phenom Desktop SEMs, complemented by expert-led lectures. We invite you to join us for an enriching exploration that combines theoretical knowledge with hands-on experience.
- [2-Day QCM-D Short Course | Alexandria, VA | June 2026](https://www.nanoscience.com/short-courses/2-day-qcm-d-short-course-alexandria-va-june-2026/): Join our specialized 2-day QCM-D (Quartz-crystal Microbalance with Dissipation monitoring) Short Course. Held in Alexandria, VA, this immersive program is designed for both experienced practitioners and newcomers, offering an in-depth exploration of both fundamental and advanced QCM-D techniques. Hosted at our state-of-the-art facilities, the course features hands-on sessions with the latest QSense instruments, complemented by expert-led lectures.
- [2026 NanoNews: SEM Edition Q1](https://www.nanoscience.com/newsletters/2026-nanonews-sem-edition-q1/): Welcome to the Scanning Electron Microscopy (SEM) edition of the Nanoscience Instruments newsletter, nanoNews! We are excited to share the latest updates from around the SEM community with you.
- [How Wettability Analysis Improves Semiconductor Package Performance and Reliability](https://www.nanoscience.com/blogs/how-wettability-analysis-improves-semiconductor-package-performance-and-reliability/): As semiconductor devices continue to shrink and packaging architectures grow more complex, surface interactions play an increasingly important role in overall performance and reliability. Wettability analysis has become a key quality and process-control tool across the semiconductor packaging workflow. From solder joint formation to underfill flow and photoresist coating behavior, understanding how liquids interact with device surfaces directly affects yield, reliability, and long-term device stability. In this article, we explore where wettability analysis fits into modern semiconductor packaging and why it has become essential for advanced manufacturing.
- [Improving Life Science EM Imaging using AI](https://www.nanoscience.com/blogs/improving-life-science-em-imaging-using-ai/): There are a number of common electron microscopy methods deployed in life sciences for imaging. The basic entry-level is Scanning Electron Microscopy (SEM) used for magnifications beyond optical microscopes, up to 1 million times magnification. Next comes Transmission Electron Microscopy (TEM) which plays a critical role in life sciences by enabling visualization of biological structures at nanometer and sub-nanometer resolution, far beyond the limits of light microscopy.
- [How Low-Volume Hot Melt Extrusion (LV-HME) Accelerates Pharmaceutical Formulation Development ](https://www.nanoscience.com/blogs/how-low-volume-hot-melt-extrusion-lv-hme-accelerates-pharmaceutical-formulation-development/): Hot melt extrusion is a process wherein active pharmaceutical ingredients (APIs) are mixed with thermoplastic polymers and other excipients, heated and mechanically sheared to form a homogeneous molten mass. This material is forced through a die and solidified into a specific shape, such as strands, films, or pellets. Originally adopted from polymer processing in the plastics industry, HME has gained strong momentum in pharmaceutical development due to its ability to improve solubility, enable controlled release, and support scalable, solvent-free manufacturing.&nbsp;
- [What are the Applications of QCM-D in Pharmaceutical Sciences? ](https://www.nanoscience.com/blogs/what-are-the-applications-of-qcm-d-in-pharmaceutical-sciences/): Quartz Crystal Microbalance with Dissipation Monitoring (QCM-D) is a powerful analytical tool that&nbsp;enables the measurement of both mass changes and viscoelastic properties of thin films at the nanoscale, in a liquid environment, thereby&nbsp;providing&nbsp;critical insights into various biological and chemical processes.&nbsp;This blog delves&nbsp;into the key applications of QCM-D in the pharmaceutical&nbsp;industry, highlighting its importance in drug development, formulation, and quality control.
- [Improving 4D-STEM Efficiency Through AI](https://www.nanoscience.com/blogs/improving-4d-stem-efficiency-through-ai/): 4D-Scanning Transmission Electron Microscopy (4D-STEM) is an advanced imaging technique in which a convergent beam electron diffraction pattern (CBED) is collected at each pixel, as a focused electron beam is scanned in 2D over the sample (Figure 1). This produces a rich, multidimensional dataset with two spatial dimensions and two reciprocal-space dimensions. 4D-STEM enables the use of several imaging and analytical methods from this one dataset, such as phase mapping, crystal orientation mapping, ptychography, and center-of-mass (COM) imaging, among others.1,2
- [AISTech 2026 | May 4-6, 2026 | Pittsburgh, PA](https://www.nanoscience.com/tradeshows/aistech-2026-may-4-6-2026-pittsburgh-pa/): At Nanoscience Instruments, we empower steelmakers by equipping them with the means to achieve comprehensive inclusion analysis in one automated system: desktop scanning electron microscopy (SEM) combined with energy dispersive X-ray spectroscopy (EDS). Automated SEM-EDS forms the functional backbone of the Phenom ParticleX Steel system, elevating high resolution imaging and microanalysis to the next level for characterizing non-metallic inclusions in steel and in other alloys like aluminum. Once detected and quantified, inclusions are automatically categorized in adherence to industry-defined standards – ASTM E45, E2142, and E2283 – and finally compiled in easy access report documents.&nbsp;&nbsp;
- [Medical Design &amp; Manufacturing South 2026  | April 22 &#8211; 23, 2026 | Charlotte, NC](https://www.nanoscience.com/tradeshows/medical-design-manufacturing-south-2026-april-22-23-2026-charlotte-nc/): Nanoscience Instruments, together with our sister company, Nanoscience Analytical, provide advanced instrumentation and contract R&amp;D services that support the design, prototyping, and scale-up of medical devices and biomedical materials. Our solutions are widely used in the medical device industry with applications in developing tissue scaffolds, vascular grafts, wound healing therapeutics, drug delivery, and implantable devices.
- [The Battery Show South 2026  | April 22 &#8211; 23, 2026 | Charlotte, NC](https://www.nanoscience.com/tradeshows/the-battery-show-south-2026-april-22-23-2026-charlotte-nc/): Nanoscience Instruments provides solutions for battery development applications through cutting-edge instrumentation and analytical services. Visit our booth for live demonstrations of desktop SEM with automated workflows designed for structural and chemical analysis of battery materials, and learn about our surface characterization tools, battery cyclers &amp; potentiostats, and process development and analytical services.
- [Society for Biomaterials 2026 | March 25 &#8211; 27, 2026 | Atlanta, GA](https://www.nanoscience.com/tradeshows/society-for-biomaterials-2026-atlanta-ga/): Nanoscience Instruments provides advanced material fabrication and characterization solutions that support biomaterials research, medical device innovation, and translational development.
- [TMS 2026 | March 16 &#8211; 18, 2026 | San Diego, CA](https://www.nanoscience.com/tradeshows/tms-2026-march-16-18-2026-san-diego-ca/): Nanoscience Instruments provides sample preparation solutions and advanced material characterization systems that support fundamental research, materials development, and failure analysis across metals, ceramics, composites, polymers, and functional materials. Our instruments are widely used in materials science and metallurgical research to enable high-resolution imaging and microstructural analysis of bulk surface or cross-sectioned samples.
- [How Does Micro-compounding Enable Medical Device Manufacturing?](https://www.nanoscience.com/blogs/how-does-micro-compounding-enable-medical-device-manufacturing/): In medical device R&amp;D, the ability to work with small quantities of high-value or experimental materials is essential. Micro-compounding has emerged as a important tool in the development and manufacturing of medical devices as it enables precise formulation and testing of polymer-based materials on a small scale, providing manufacturers with the flexibility to optimize performance, biocompatibility, and regulatory compliance before moving to full-scale production. Micro-compounding allows for rapid iteration of formulations with minimal material and waste.
- [Optimizing Dispenser Materials for Contact Angle Measurements](https://www.nanoscience.com/blogs/optimizing-dispenser-materials-for-contact-angle-measurements/): Contact angle measurement is essential for characterizing the wettability and surface energy of materials, providing critical insights into how liquids interact with solid surfaces. This is vital for applications ranging from coatings, adhesives, and packaging to biomedical devices and semiconductors. Contact angle measurements help quantify hydrophobicity or hydrophilicity, assess surface treatments, optimize adhesion, and predict liquid spreading or droplet behavior.1 By understanding these interactions, researchers and engineers can design surfaces with controlled wetting properties, improve product performance, and ensure reliability in real-world applications.
- [Batch Micro-Compounding for Lab-Scale Polymer Processing](https://www.nanoscience.com/blogs/batch-micro-compounding-for-lab-scale-polymer-processing/): Developing new polymer materials often involves a difficult transition from concept to a testable prototype. During this early phase, researchers typically conduct multiple iterations, refining formulations, adjusting processing parameters, and evaluating material compatibility.1 Relying on large-scale production equipment for these exploratory steps can be inefficient and time-consuming. Conventional twin-screw extruders, for instance, require substantial material quantities, involve lengthy setup times, and are impractical for rapid screening of numerous formulation variations.
- [Desktop SEM Rentals: Increasing Accessibility to Advanced Materials Analysis](https://www.nanoscience.com/customer-stories/desktop-sem-rentals-increasing-accessibility-to-advanced-materials-analysis/): Scanning Electron Microscopy (SEM) is a powerful imaging technique that enables researchers and engineers to visualize surface structures at nanometer to micrometer scales. By scanning a focused electron beam across a specimen, SEM delivers high-resolution images with exceptional depth of field, making it a critical tool for materials analysis, quality control, and failure investigation. Its ability to reveal fine morphological details, composition contrast, and microstructural features allows users to better understand how materials behave, identify defects early, and accelerate research and development.
- [2025 NanoNews: Tensiometry Edition Q4](https://www.nanoscience.com/newsletters/2025-nanonews-tensiometry-edition-q4/): In this winter newsletter, you will find our new video series detailing each of the measurement types available on both the Attention Theta optical tensiometers and the Attension Sigma force tensiometers. If you are interested in more updates about tensiometry, we invite you to follow us on LinkedIn!
- [2025 NanoNews: SEM Edition Q4](https://www.nanoscience.com/newsletters/2025-nanonews-sem-edition-q4/): In this winter newsletter, you will find recent webinars, white papers, and blogs that highlight the applications of Phenom desktop SEMs across a wide variety of industries and research applications. Additionally, you can find information about our 2-day SEM short courses in Alexandria, Virginia and Phoenix, Arizona. 
- [How Much Does a QCM-D System Cost?](https://www.nanoscience.com/blogs/how-much-does-a-qcm-d-system-cost/): Quartz crystal microbalance with dissipation monitoring (QCM-D) instruments are powerful tools for real-time, label-free analysis of surface interactions and material properties at the molecular level. More specifically, QCM-D systems quantify nanoscale or even picoscale mass changes and viscoelastic properties in liquid-phase adsorption or desorption studies.1,2 If you are curious about adding QCM-D to your lab, you might be wondering: what factors influence the instrument’s cost, and what should you budget for?
- [Wettability Analysis in Semiconductor Processing](https://www.nanoscience.com/blogs/wettability-analysis-in-semiconductor-processing/): Silicon wafers are the backbone of modern electronics, forming the base material for integrated circuits, microchips, and sensors. As device features continue to shrink into the nanometer range, the cleanliness and chemical uniformity of wafer surfaces have become a critical factor in ensuring high manufacturing yields and reliable device performance. Even the smallest trace of organic residue, metallic contamination, or particulate matter can alter electrical properties and compromise production.
- [2025 NanoNews: QCM-D Edition Q4](https://www.nanoscience.com/newsletters/2025-nanonews-qcm-d-edition-q4/): Welcome to the Quartz Crystal Microbalance with Dissipation monitoring (QCM-D) edition of the Nanoscience Instruments newsletter, nanoNews. We are excited to share the latest updates from around the QCM-D community with you!
- [2025 NanoNews: Electrospinning Edition Q4](https://www.nanoscience.com/newsletters/2025-nanonews-electrospinning-edition-q4/): Welcome to the electrospinning edition of the Nanoscience Instruments newsletter, nanoNews. We are excited to share the latest updates from the community with you!
- [Medical Design &amp; Manufacturing West 2026  | Feb. 3 &#8211; 5, 2026 | Anaheim, CA](https://www.nanoscience.com/tradeshows/medical-design-manufacturing-west-2026-feb-3-5-2025-anaheim-ca/): Nanoscience Instruments, together with our sister company, Nanoscience Analytical, provide advanced instrumentation and contract R&amp;D services that support the design, prototyping, and scale-up of medical devices and biomedical materials. Our solutions are widely used in the medical device industry with applications in developing tissue scaffolds, vascular grafts, wound healing therapeutics, drug delivery, and implantable devices.
- [Ten Factors that Influence the Cost of QCM-D Systems](https://www.nanoscience.com/blogs/ten-factors-that-influence-the-cost-of-qcm-d-systems/): Quartz crystal microbalance with dissipation monitoring (QCM-D) instruments are powerful tools for real-time, label-free analysis of molecular interactions on a surface in a liquid environment. QCM-D systems can quantify nanoscale mass changes and viscoelastic properties of thin films on the surface in adsorption or desorption studies.1,2 If you are curious about adding QCM-D to your lab, you might be wondering: what factors influence the instrument’s data quality and price?
- [The Hidden Costs of Polymer Compounding in R&amp;D](https://www.nanoscience.com/blogs/the-hidden-costs-of-polymer-compounding-in-rd/): Polymer compounding is fundamental to developing new polymeric materials in sectors such as automotive, aerospace, medical devices, and packaging. While traditional compounding methods remain prevalent in research and development (R&amp;D) environments, they often come with hidden costs that impact time and resources.
- [2-Day SEM Short Course | Alexandria, VA | April 2026](https://www.nanoscience.com/short-courses/2-day-sem-short-course-alexandria-va-april-2026/): Explore the microscopic world in our specialized 2-day Scanning Electron Microscopy (SEM) Short Course. Held in Alexandria, VA, this immersive program is designed for both experienced practitioners and newcomers, offering an in-depth exploration of both fundamental and advanced SEM techniques. Hosted at our state-of-the-art facilities, the course features hands-on sessions with the latest Phenom Desktop SEMs, complemented by expert-led lectures. We invite you to join us for an enriching exploration that combines theoretical knowledge with hands-on experience.
- [Broad Ion Beam vs. Focused Ion Beam Polishing: Choosing the Right Technique for Sample Preparation](https://www.nanoscience.com/blogs/broad-ion-beam-vs-focused-ion-beam-polishing-choosing-the-right-technique-for-sample-preparation/): When preparing samples for electron microscopy, the choice of method directly impacts the clarity and reliability of the images. Imperfections such as roughness, contamination, or surface damage can obscure fine details and lead to misinterpreted data.
- [What is a Twin Screw Extruder? Types, Applications, and Benefits Explained](https://www.nanoscience.com/blogs/what-is-a-twin-screw-extruder-types-applications-and-benefits-explained/): Twin screw extruders are among the most versatile processing equipment used in polymer compounding, pharmaceutical hot-melt extrusion, food production, and advanced materials research.&nbsp; They provide the precision and flexibility needed for complex formulations. Twin screw extruders offer superior mixing, enhanced process control, and facile scalability making them indispensable in industries where performance and consistency are critical.&nbsp;
- [2-Day SEM Short Course | Phoenix, AZ | February 2026](https://www.nanoscience.com/short-courses/2-day-sem-short-course-phoenix-az-february-2026/): Explore the microscopic world in our specialized 2-day Scanning Electron Microscopy (SEM) Short Course. Held in Phoenix, AZ, this immersive program is designed for both experienced practitioners and newcomers, offering an in-depth exploration of both fundamental and advanced SEM techniques. Hosted at our state-of-the-art facilities, the course features hands-on sessions with the latest Phenom Desktop SEMs, complemented by expert-led lectures. We invite you to join us for an enriching exploration that combines theoretical knowledge with hands-on experience.
- [ISTFA 2025  | November 17-19, 2025 | Pasadena, CA](https://www.nanoscience.com/tradeshows/istfa-2025-november-17-19-2025-pasadena-ca/): Stop by and visit Nanoscience Instruments at booth #418 for the International Symposium for Testing and Failure Analysis (ISFTA) and discover how our class-leading microscopy solutions can elevate your material analysis!
- [Optical Microscopy vs SEM for Technical Cleanliness Analysis](https://www.nanoscience.com/blogs/optical-microscopy-vs-sem-for-technical-cleanliness-analysis/): The performance of sensitive systems such as engines, hydraulics, electronics, and medical devices can be compromised in cases of particle contamination; this reduces product quality and introduces risks of failure. To prevent this, system components must meet standards of technical cleanliness (TC) to be accepted for use. Particulate quantity, size, and hardness are all considered when accepting or rejecting a component. Parts cleanliness can be evaluated with technical cleanliness analysis, also known as particulate contamination analysis.
- [Choosing Between Optical and SEM Techniques for Particle Characterization](https://www.nanoscience.com/blogs/choosing-between-optical-and-sem-techniques-for-particle-characterization/): Particle analysis, which typically focuses on parameters such as size, shape, distribution, concentration, and composition, plays a critical role across a wide range of industries, from pharmaceuticals and biotechnology to advanced manufacturing and materials engineering.1,2 Two primary methods are commonly used to analyze particles: optical methods and scanning electron microscopy (SEM). While both aim to quantify size distributions and morphology, they differ in resolution, sample preparation, throughput, cost, and the depth of information obtained. This article provides an overview of how each technique works, the strength and weakness of each and when they are best used for particle characterization.
- [The Battery Show 2025  | October 6-9, 2025 | Detroit, MI](https://www.nanoscience.com/tradeshows/the-battery-show-south-2025-october-6-9-2025-detroit-mi/): Nanoscience Instruments provides solutions for battery development applications through cutting-edge instrumentation and analytical services. Visit our booth for live demonstrations of desktop SEM with automated workflows designed for structural and chemical analysis of battery materials, and learn about our surface characterization tools, battery cyclers &amp; potentiostats, and process development and analytical services.
- [2-Day QCM-D Short Course | Alexandria, VA | Feb. 2026](https://www.nanoscience.com/short-courses/2-day-qcm-d-short-course-alexandria-va-feb-2026/): Join our specialized 2-day QCM-D (Quartz-crystal Microbalance with Dissipation monitoring) Short Course. Held in Alexandria, VA, this immersive program is designed for both experienced practitioners and newcomers, offering an in-depth exploration of both fundamental and advanced QCM-D techniques. Hosted at our state-of-the-art facilities, the course features hands-on sessions with the latest QSense instruments, complemented by expert-led lectures.
- [What are the Key Applications of QCM-D?](https://www.nanoscience.com/blogs/what-are-the-key-applications-of-qcm-d/): Quartz Crystal Microbalance with Dissipation monitoring (QCM-D) has revolutionized surface science by enabling real-time analysis of molecular interactions. However, traditional QCM-D workflows often involve time-consuming manual processes that introduce variability and inefficiency. In most QCM-D systems, sensor mounting, determining the resonance frequencies, stabilizing the baseline in air, priming the sensor, and establishing the baseline in liquids are performed manually.
- [A Guide to Particle Analysis: Key Methods, Applications, and Benefits](https://www.nanoscience.com/blogs/a-guide-to-particle-analysis-key-methods-applications-and-benefits/): Particle analysis is the measurement and characterization of particles in a sample. Particle analysis typically focuses on properties such as particle size and size distribution, shape and morphology, count, concentration, and composition. Particle analysis is used to ensure quality control, understand material properties, and optimize production processes.
- [Desktop SEMs: Advanced Imaging Without the Infrastructure](https://www.nanoscience.com/blogs/desktop-sems-advanced-imaging-without-the-infrastructure/): Scanning Electron Microscopes (SEMs) are indispensable tools for analyzing surface morphology, materials composition, and microstructural details at high resolution. They are used extensively across research institutions, manufacturing lines, forensic labs, environmental monitoring stations, and more. However, conventional floor-model SEMs come with significant infrastructure requirements, such as dedicated space, environmental conditioning, and auxiliary systems, that often limit where and how they can be deployed. Desktop SEMs offer many of the same features as floor-model systems in a compact design that can be accommodated virtually in any lab space.
- [2025 NanoNews: SEM Edition Q2](https://www.nanoscience.com/newsletters/2025-nanonews-sem-edition-q2/): We&#039;re pleased to share the latest edition of nanoNews! In the second quarter of the 2025 newsletter, you&#039;ll find our webinar resources, event news, and our newest articles and technical notes - all focused on Scanning Electron Microscopy (SEM).
- [2025 NanoNews: QCM-D Edition Q2](https://www.nanoscience.com/newsletters/2025-nanonews-qcm-d-edition-q2/): Welcome to the Quartz Crystal Microbalance with Dissipation monitoring (QCM-D) edition of the Nanoscience Instruments newsletter, nanoNews. We are excited to share the latest updates from around the QCM-D community with you!
- [2025 NanoNews: Electrospinning Edition Q2](https://www.nanoscience.com/newsletters/2025-nanonews-electrospinning-edition-q2/): This second quarter Electrospinning edition is packed with new blogs, webinars, and a new collector for the LE-100!
- [2025 NanoNews: Tensiometry Edition Q2](https://www.nanoscience.com/newsletters/2025-nanonews-tensiometry-edition-q2/): Welcome to the second quarter Tensiometry edition of the Nanoscience Instruments newsletter, nanoNews. We are excited to share the latest updates from around the Tensiometry community with you!
- [Fabricating Nanofibers: Electrospinning Vs Blow Spinning ](https://www.nanoscience.com/blogs/fabricating-nanofibers-electrospinning-vs-blow-spinning/): Nanofibers, with their high surface area-to-volume ratio, tunable porosity, and mechanical flexibility, are increasingly used in diverse applications including filtration, biomedical devices, energy storage, and smart textiles. Among the many fabrication techniques available, electrospinning and blow spinning have emerged as two of the most prominent methods for producing nanofibers from polymeric solutions. While both techniques can yield continuous nanofibers, they differ significantly in their operational principles, equipment requirements, scalability, fiber morphology, and suitability for different applications.
- [American Chemical Society (ACS) Fall 2025 | August 18-20, 2025 | Washington, DC](https://www.nanoscience.com/tradeshows/american-chemical-society-acs-fall-2025-august-18-20-2025-washington-dc/): Meet us in Booth #2719 at the American Chemical Society’s Fall Meeting!  &nbsp;
- [Enhancing Efficacy of Bipolar Membranes through Electrospinning](https://www.nanoscience.com/blogs/enhancing-efficacy-of-bipolar-membranes-through-electrospinning/): Electrospinning has emerged as a transformative technique for fabricating fibrous materials with highly controlled geometries. This method, characterized by its ability to produce ultrafine fibers from various materials, has garnered widespread attention across industries, including healthcare, energy, and materials science. A particularly exciting aspect of electrospinning is its capacity to create complex geometric structures composed of nanoscale and microscale fibers, which significantly enhance their functionality for advanced applications. Traditional electrospinning produces planar surfaces composed of randomly oriented fibers but advancements in the field have enabled the fabrication of more sophisticated structures. In this blog we will delve into some of the complex geometric structures that can be fabricated by electrospinning and their different applications.
- [Microscopy &amp; Microanalysis 2025 | July 28 – July 31, 2025 | Salt Lake City, Utah](https://www.nanoscience.com/tradeshows/microscopy-microanalysis-2025-july-28-july-31-2025-salt-lake-city-utah/): Join us in Salt Lake City, Utah for the highlight of the microscopy calendar – M&amp;M 2025! Nanoscience Instruments is back for this annual summertime conference, and this time we’re showcasing in Booth #1925.
- [Evaluating Alternative Techniques for Real-Time Monitoring of Molecular Interactions at Surfaces](https://www.nanoscience.com/blogs/evaluating-alternative-techniques-for-real-time-monitoring-of-molecular-interactions-at-surfaces/): Understanding molecular interactions at surfaces is essential for advancing fields such as biosensing, materials science, and drug discovery. These interactions—ranging from protein-ligand binding to polymer adsorption—can reveal crucial information about binding kinetics, affinity, and conformational changes. Surface-sensitive analytical techniques enable researchers to monitor these events in real time and under physiologically relevant conditions, without the need for labeling. By characterizing how molecules behave at interfaces, scientists can design better materials, improve sensor performance, and develop more effective therapeutics.
- [ACS Colloids 2025 | June 22-26, 2025 | Edmonton, AB](https://www.nanoscience.com/tradeshows/acs-colloids-2025-june-22-26-2025-edmonton-ab/): Mark your calendars for the 99th ACS Colloid and Surface Science Symposium! The event promises to be an unparalleled gathering of researchers, scholars, and professionals from around the world, focusing on the cutting-edge advancements in the field of colloid and surface science. 
- [Nanoscience Instruments Becomes Exclusive North American Distributor for SenseAI](https://www.nanoscience.com/press-releases/nanoscience-instruments-becomes-exclusive-north-american-distributor-for-senseai/): SenseAI, the compressed sensing software transforming the way electron microscopy images are captured, is excited to announce a new exclusive distribution agreement with Nanoscience Instruments, leaders in microscopy and surface science instrumentation.&nbsp;&nbsp;
- [2-Day QCM-D Short Course | Alexandria, VA | September 2025](https://www.nanoscience.com/short-courses/2-day-qcm-d-short-course-alexandria-va-september-2025/): Join our specialized 2-day QCM-D (Quartz-crystal Microbalance with Dissipation monitoring) Short Course. Held in Alexandria, VA, this immersive program is designed for both experienced practitioners and newcomers, offering an in-depth exploration of both fundamental and advanced QCM-D techniques. Hosted at our state-of-the-art facilities, the course features hands-on sessions with the latest QSense instruments, complemented by expert-led lectures.
- [2-Day SEM Short Course | Phoenix, AZ | November 2025](https://www.nanoscience.com/short-courses/2-day-sem-short-course-phoenix-az-november-2025/): Explore the microscopic world in our specialized 2-day Scanning Electron Microscopy (SEM) Short Course. Held in Phoenix, AZ during the fall, this immersive program is designed for both experienced practitioners and newcomers, offering an in-depth exploration of both fundamental and advanced SEM techniques. Hosted at our state-of-the-art facilities, the course features hands-on sessions with the latest Phenom Desktop SEMs, complemented by expert-led lectures.
- [Nanoscience &amp; Xplore Instruments Announce Strategic Partnership for Distribution of Polymer Micro Compounding Equipment](https://www.nanoscience.com/press-releases/nanoscience-xplore-instruments-announce-strategic-partnership-for-distribution-of-polymer-micro-compounding-equipment/): Nanoscience Instruments, a leading provider of scientific instrumentation and service solutions for customers in the United States and Canada, is excited to announce a new partnership with Xplore Instruments BV, a pioneering manufacturer of polymer micro compounders and post-die shaping instruments based in the Netherlands. This collaboration expands Nanoscience Instruments&#039; suite of polymer processing solutions, offering researchers and product developers access to scalable, cutting-edge micro compounding technologies.
- [Maximizing Efficiency in Polymer R &amp; D with Micro-compounders](https://www.nanoscience.com/blogs/maximizing-efficiency-in-polymer-r-d-with-microcompounders/): In polymer processing and material research, achieving uniform dispersion and distribution of additives and precise formulation control is crucial for developing advanced materials. This is achieved by a process called compounding. &nbsp;
- [Desktop Scanning Electron Microscopy in Geology](https://www.nanoscience.com/blogs/desktop-sem-in-geology/): Scanning Electron Microscopy (SEM) is a versatile tool in geology used in high-resolution imaging and chemical analysis of rocks, minerals, and microfossils. SEM provides detailed images of mineral morphology and surface textures, which are essential for identifying minerals and understanding their growth patterns. Studying the deformation features using an SEM helps reconstruct the geological history of rocks. SEM reveals clay mineral morphology that are crucial for evaluating reservoir quality in petroleum geology or aquifer studies. In paleontology and microfossil analysis, SEM is often used to examine the surface features of microfossils and biomineralized structures. Precise mineral classification can be achieved when combining Energy-Dispersive X-ray Spectroscopy (EDS) with SEM.
- [Enhancing SEM Performance with Ion Milling Technology](https://www.nanoscience.com/blogs/enhancing-sem-performance-with-ion-milling-technology/): In material science, cross-section polishing is a critical method to enable the detailed examination of a sample material’s microstructure. This technique is essential for understanding the composition, properties, and potential applications of various materials, from metals and ceramics to semiconductors and battery materials. By providing a pristine, flat, and highly reflective surface, cross-section polishing enables researchers and engineers to see inside the microscopic world of materials with precision and clarity.  
- [2-Day SEM Short Course | Alexandria, VA | September 2025](https://www.nanoscience.com/short-courses/2-day-sem-short-course-alexandria-va-september-2025/): Explore the microscopic world in our specialized 2-day Scanning Electron Microscopy (SEM) Short Course. Held in Alexandria, VA, this immersive program is designed for both experienced practitioners and newcomers, offering an in-depth exploration of both fundamental and advanced SEM techniques. Hosted at our state-of-the-art facilities, the course features hands-on sessions with the latest Phenom Desktop SEMs, complemented by expert-led lectures.
- [Benchtop STEM-in-SEM: A Powerful Tool for Tissue Ultrastructure Studies](https://www.nanoscience.com/blogs/benchtop-stem-in-sem-a-powerful-tool-for-tissue-ultrastructure-studies/): Understanding the ultrastructure of biological tissues is essential for advancing medical research, disease diagnostics, and drug development. Traditionally, histological techniques such as optical microscopy have been the standard for tissue analysis. While these methods provide valuable insights, they are often limited in resolution, making it difficult to visualize fine structural details at the nanometer scale. Transmission electron microscopy (TEM) has long been the gold standard for ultrastructural imaging,1 but conventional TEM workflows are complex, requiring dedicated infrastructure and specialized expertise.
- [Essentials of Polymer Compounding](https://www.nanoscience.com/blogs/essentials-of-polymer-compounding/): Polymer compounding is a fundamental process in materials engineering that involves blending polymers with various additives to enhance their properties and performance. This allows manufacturers to tailor polymer materials to meet specific requirements for different industries including automotive, aerospace, healthcare and consumer goods. By tailoring the mechanical, thermal, and chemical properties of polymers, their range of applications can be significantly increased.
- [Automated SEM: The Future of Particle Analysis](https://www.nanoscience.com/blogs/automated-sem-the-future-of-particle-analysis/): Particle analysis involves characterizing the size, morphology, and composition of powders and particulate matter to describe their properties in a precise and statistically significant manner. Some of the most common areas where particle analysis is critical are in advanced manufacturing, forensic analysis, and environmental applications.
- [2025 NanoNews: SEM Edition Q1](https://www.nanoscience.com/newsletters/2025-nanonews-sem-edition-q1/): We&#039;re pleased to share the latest edition of nanoNews! In the first quarter of the 2025 newsletter, you&#039;ll find our webinar resources, event news, and our newest articles and technical notes - all focused on Scanning Electron Microscopy (SEM).
- [AISTech 2025 | May 5-7, 2024 | Nashville, TN](https://www.nanoscience.com/tradeshows/aistech-2025-may-5-7-2024-nashville-tn/): At Nanoscience Instruments, we empower steelmakers by equipping them with the means to achieve comprehensive inclusion analysis in one automated system: desktop scanning electron microscopy (SEM) combined with energy dispersive X-ray spectroscopy (EDS). Automated SEM-EDS forms the functional backbone of the Phenom ParticleX Steel system, elevating high resolution imaging and microanalysis to the next level for characterizing non-metallic inclusions in steel and in other alloys like aluminum. Once detected and quantified, inclusions are automatically categorized in adherence to industry-defined standards – ASTM E45, E2142, and E2283 – and finally compiled in easy access report documents.&nbsp;&nbsp;
- [8 Factors That Affect the Cost of a Force Tensiometer](https://www.nanoscience.com/blogs/8-factors-that-affect-the-cost-of-a-force-tensiometer/): A force tensiometer is an instrument that uses a highly sensitive analytical balance and specialized probes to characterize several key interfacial properties. Even though it is most used to measure surface and interfacial tension, force tensiometers are capable of a variety of other measurements including contact angle, adhesion and cohesion, critical micelle concentration, and powder wettability.
- [5 Reasons to Use a Desktop STEM to Screen Negatively Stained Samples](https://www.nanoscience.com/blogs/5-reasons-to-use-a-desktop-stem-to-screen-negatively-stained-samples/): Cryo-electron microscopy (cryo-EM) is a powerful imaging technique used to determine the structure of biological macromolecules, viruses, and cellular components at near-atomic resolution. Unlike traditional electron microscopy, which requires heavy metal staining or dehydration, cryo-EM preserves biological samples in their native hydrated state by rapidly freezing them.
- [Advanced Automation Features of QSense Omni for Maximizing Efficiency ](https://www.nanoscience.com/blogs/advanced-automation-features-of-qsense-omni-for-maximizing-efficiency/): Quartz Crystal Microbalance with Dissipation monitoring (QCM-D) has revolutionized surface science by enabling real-time analysis of molecular interactions. However, traditional QCM-D workflows often involve time-consuming manual processes that introduce variability and inefficiency. In most QCM-D systems, sensor mounting, determining the resonance frequencies, stabilizing the baseline in air, priming the sensor, and establishing the baseline in liquids are performed manually.
- [The Battery Show South 2025  | April 16-17, 2025 | Atlanta, GA](https://www.nanoscience.com/tradeshows/the-battery-show-south-2025-april-16-17-2025-atlanta-ga/): Nanoscience Instruments provides solutions for battery development applications through cutting-edge instrumentation and analytical services. Visit our booth for live demonstrations of desktop SEM with automated workflows designed for structural and chemical analysis of battery materials, and learn about our surface characterization tools, battery cyclers &amp; potentiostats, and process development and analytical services.
- [Fabricating Complex Geometries with Electrospinning](https://www.nanoscience.com/blogs/fabricating-complex-geometries-with-electrospinning/): Electrospinning has emerged as a transformative technique for fabricating fibrous materials with highly controlled geometries. This method, characterized by its ability to produce ultrafine fibers from various materials, has garnered widespread attention across industries, including healthcare, energy, and materials science. A particularly exciting aspect of electrospinning is its capacity to create complex geometric structures composed of nanoscale and microscale fibers, which significantly enhance their functionality for advanced applications. Traditional electrospinning produces planar surfaces composed of randomly oriented fibers but advancements in the field have enabled the fabrication of more sophisticated structures. In this blog we will delve into some of the complex geometric structures that can be fabricated by electrospinning and their different applications.
- [5 Benefits of Scanning Electron Microscopy for Particle Analysis](https://www.nanoscience.com/blogs/5-benefits-of-scanning-electron-microscopy-for-particle-analysis/): Particle analysis is a critical process in many industries, from pharmaceutical formulation and nanomaterials development to forensic investigations and industrial manufacturing. Understanding the size, shape, and composition of particles plays a crucial role in ensuring product quality, optimizing performance, and meeting regulatory requirements.
- [Unmatched Sensitivity: How QSense Omni Redefines QCM-D Performance](https://www.nanoscience.com/blogs/unmatched-sensitivity-how-qsense-omni-redefines-qcm-d-performance/): Interactions at surfaces and interfaces are crucial in many fields, including environmental science, biopharmaceutical research, materials science, catalysis, and nanotechnology. The ability to detect minute changes in mass, viscoelastic properties, and interfacial phenomena can be crucial in determining the success of groundbreaking research. Understanding these interactions allows for the design of better materials and devices with tailored properties.
- [American Chemical Society (ACS) Spring 2025  | March 24 &#8211; 26, 2025 | San Diego, CA](https://www.nanoscience.com/tradeshows/american-chemical-society-2025-march-24-26-2025-san-diego-ca/): Meet us in Booth #3625 at the American Chemical Society’s Spring Meeting!&nbsp;&nbsp;
- [Particle Analysis Techniques: What Makes SEM Unique](https://www.nanoscience.com/blogs/particle-analysis-techniques-what-makes-sem-unique/): Particle analysis involves measuring various characteristics of powders or particulates, including size, shape, and composition. A wide variety of industries rely on particle analysis for ensuring product functionality and safety including the production of automobiles, batteries, pharmaceuticals, and electronics.
- [Electrospinning: A Versatile Technique for Fabricating Diverse Fiber Microstructures](https://www.nanoscience.com/blogs/electrospinning-a-versatile-technique-for-fabricating-diverse-fiber-microstructures/): Electrospinning is a powerful and versatile technique used to produce nonwoven ultrafine fibers with controlled microstructures. Electrospinning can be used to fabricate fibers of different diameters ranging from 20 nm to more than 10 µm. Fibers can be fabricated from solution, emulsion, suspension, sol-gel or slurry composed from different materials like polymers (natural, semi-synthetic and synthetic), ceramics, metals and/or different types of additives. Its ability to process a wide range of materials and produce fibers with tailored properties has made it a cornerstone in applications like textiles, medical &amp; healthcare, energy, filtration, packaging, automotive, and aerospace.
- [Large-area Mapping Workflows in Scanning Electron Microscopy (SEM)](https://www.nanoscience.com/blogs/lage-area-mapping-workflows-in-scanning-electron-microscopy-sem/): Large-area imaging in scanning electron microscopy (SEM) is a technique for exploring expansive regions of a sample at high resolution, making it invaluable in fields such as materials science, electronics, and life sciences. However, capturing high-resolution images across large sample areas presents unique challenges, including time constraints and data management. This is where image stitching algorithms come into play, enabling researchers to seamlessly combine multiple high-magnification images into a single, comprehensive view (often referred to as a large-area map). In this blog, we’ll dive into how large-area mapping works, explore various image stitching software and workflows, and discuss how these techniques can improve efficiency and enhance imaging results.
- [Evaluating Medical Device Coatings with Picoliter Droplets](https://www.nanoscience.com/blogs/evaluating-medical-device-coatings-with-picoliter-droplets/): Coatings for invasive medical devices are critical in ensuring their safety, performance, and functionality. These coatings address the unique challenges associated with devices that directly interact with tissue or blood. Coatings enhance the compatibility of invasive devices, such as implants and stents, with the human body. They minimize immune responses, inflammation, and tissue damage by creating a biologically inert interface between the device and surrounding tissues. Hydrophilic coatings on devices such as catheters, guidewires, and endoscopic tools provide a lubricious surface, enabling smoother insertion and navigation through tissues while minimizing trauma. Specialized coatings, such as heparin or polymer-based films, improve hemocompatibility by reducing the risk of clot formation and platelet adhesion on blood-contacting devices like vascular grafts and heart valves.
- [2-Day SEM Short Course | Alexandria, VA | May 2025](https://www.nanoscience.com/short-courses/2-day-sem-short-course-alexandria-va-may-2025/): Explore the microscopic world in our specialized 2-day Scanning Electron Microscopy (SEM) Short Course. Held in Alexandria, VA, this immersive program is designed for both experienced practitioners and newcomers, offering an in-depth exploration of both fundamental and advanced SEM techniques. Hosted at our state-of-the-art facilities, the course features hands-on sessions with the latest Phenom Desktop SEMs, complemented by expert-led lectures.
- [2024 NanoNews: Tensiometry Edition Q4](https://www.nanoscience.com/newsletters/2024-nanonews-tensiometry-edition-q4/): Welcome to the fourth quarter Tensiometry edition of the Nanoscience Instruments newsletter, nanoNews. We are excited to share the latest updates from around the Tensiometry community with you! In this newsletter you will find recent Masterclasses, blogs, and white papers that expand on surface roughness in contact angle measurements, measuring dynamic contact angles, and emphasizing the key factors for choosing an Attension Optical or Force Tensiometer.
- [2024 NanoNews: QCM-D Edition Q4](https://www.nanoscience.com/newsletters/2024-nanonews-qcm-d-edition-q4/): Welcome to the Quartz Crystal Microbalance with Dissipation monitoring (QCM-D) edition of the Nanoscience Instruments newsletter, nanoNews. We are excited to share the latest updates from around the QCM-D community with you! In this fourth quarter newsletter you will find recent webinars, blogs, and publications that highlight several use cases of QSense QCM-D across a variety of industries and research applications.
- [2024 NanoNews: Electrospinning Edition Q4](https://www.nanoscience.com/newsletters/2024-nanonews-electrospinning-edition-q4/): This fourth quarter Electrospinning edition is packed with new blogs, webinars, and videos. From demonstrating the formation and control of the Taylor cone to a time-lapse showing the possibility of scaling-up on the LE-500.
- [2024 NanoNews: SEM Edition Q4](https://www.nanoscience.com/newsletters/2024-nanonews-sem-edition-q4/): We&#039;re pleased to share the latest edition of nanoNews! In the third quarter newsletter, you&#039;ll find our webinar resources, event news, and our newest articles and technical notes -- all focused on Scanning Electron Microscopy (SEM).
- [Analyzing Surface Interactions Using QCM-D ](https://www.nanoscience.com/blogs/analyzing-surface-interactions-using-qcm-d/): Quartz Crystal Microbalance with Dissipation Monitoring (QCM-D) is a versatile analytical technique that can provide real-time, quantitative data on mass changes and viscoelastic properties of thin films and surfaces, making it an essential tool in many scientific and industrial fields.
- [How Much Does a Contact Angle Meter Cost? ](https://www.nanoscience.com/blogs/how-much-does-a-contact-angle-meter-cost/): Optical tensiometers, also referred to as goniometers, drop shape analyzers, or contact angle meters, are indispensable instruments used in scientific and industrial applications requiring precise surface and interfacial tension measurements. Their role spans industries such as material science, coatings, pharmaceuticals, and petrochemicals, making them a critical investment for many organizations. However, the cost of an optical tensiometer can vary significantly based on factors like functionality, accuracy, automation, and software capabilities. This blog explores the cost range of optical tensiometers and the key factors influencing pricing, helping buyers understand what to expect and how to make informed purchasing decisions. 
- [Medical Design &amp; Manufacturing West 2025  | Feb. 4-6, 2025 | Anaheim, CA](https://www.nanoscience.com/tradeshows/medical-design-manufacturing-west-2025-feb-4-6-2025-anaheim-ca/): Nanoscience Instruments and our sister company, Nanoscience Analytical, provide cutting-edge instrumentation and process development services to enhance the production of medical devices and biomedical products such as tissue scaffolds, vascular grafts, wound healing therapeutics, and more.
- [How does Electrospinning Complement 3D Printing? ](https://www.nanoscience.com/blogs/how-does-electrospinning-complement-3d-printing/): In the world of material fabrication, various techniques have emerged to create complex and functional materials for a wide range of applications, from medical devices to industrial components. Among these techniques, electrospinning and 3D printing have gained significant attention. While both methods offer unique advantages, they also present different challenges and limitations. In this blog we summarize the two techniques and deliberate if electrospinning can enhance the functionality of 3D fabricated devices.  
- [2-Day SEM Short Courses | Phoenix, AZ | February 2025](https://www.nanoscience.com/short-courses/2-day-sem-short-courses-phoenix-az-february-2025/): Explore the microscopic world in our specialized 2-day Scanning Electron Microscopy (SEM) Short Course. Held in Phoenix, AZ, this immersive program is designed for both experienced practitioners and newcomers, offering an in-depth exploration of both fundamental and advanced SEM techniques. Hosted at our state-of-the-art facilities, the course features hands-on sessions with the latest Phenom Desktop SEMs, complemented by expert-led lectures.
- [9 Key Factors to Consider when Selecting a Drop Shape Analyzer](https://www.nanoscience.com/blogs/9-key-factors-to-consider-when-selecting-a-drop-shape-analyzer/): Optical tensiometers, also referred to as goniometers, contact angle meters, or drop shape analyzers, are essential tools in materials science, enabling precise measurements of surface and interfacial tension of liquids and solids. Their use spans industries from coatings and electronics to medical devices, impacting research accuracy and industrial decision-making. Choosing the right tensiometer can optimize lab efficiency and improve data reliability. But selecting the right optical tensiometer may seem overwhelming with so many options with different capabilities that are available.  Here’s a breakdown of the primary considerations to make an informed investment in the best optical tensiometer for your needs.
- [Electrospinning Biocompatible Materials for Implantable Devices ](https://www.nanoscience.com/blogs/electrospinning-biocompatible-materials-for-implantable-devices/): The need for implantable devices and biocompatible materials is driven by the demand for advanced medical solutions that can repair, replace, or support damaged tissues while minimizing the risk of rejection and complications. These technologies are essential for improving patient outcomes in a wide range of surgical and therapeutic procedures. Electrospinning, a versatile technique for producing ultra-fine fibers, is a powerful tool in the design, fabrication, and modification of implantable medical devices. By creating fibers at the nanoscale, electrospinning enables production of materials with high surface area, porosity, and unique mechanical properties, allowing mimicry of natural tissues. Electrospun materials can not only improve the integration of implants with surrounding tissue, but also allow for controlled drug delivery and targeted healing, making electrospinning a key technology in advancing the effectiveness and safety of implantable medical devices. 
- [SEM Characterization of Recycled Materials for the Circular Economy ](https://www.nanoscience.com/blogs/sem-characterization-of-recycled-materials-for-the-circular-economy/): In the age of climate change and resource depletion, the circular economy is increasingly gaining attention. It promotes the reuse, recycling, and repurposing of materials to create sustainable production and consumption systems. One essential tool that enables this process is Scanning Electron Microscopy (SEM), which provides detailed insights into the structural and compositional properties of recycled materials. SEM provides a powerful and accessible solution for detailed analysis of recycled material microstructures, surface characteristics, and elemental composition, making it an essential tool for both R&amp;D and quality control in recycling industries.
- [ChemiSEM: Streamlining Real-Time Particle Analysis and Decision Making ](https://www.nanoscience.com/blogs/chemisem-streamlining-real-time-particle-analysis-and-decision-making/): Energy dispersive spectroscopy (EDS) is a microanalysis technique that provides localized elemental composition data, typically used in conjunction with scanning electron microscopy (SEM). While SEM-EDS can provide elemental composition at the level of individual particles, it involves a time-consuming multi-step process ​​. ChemiSEM is an advanced technology that combines SEM and EDS to deliver ultra-fast and dynamically integrated results. In this blog, we will explore the technical advantages of SEM-EDS in microscopic particle analysis and examine how ChemiSEM enhances efficiency and accelerates data-driven decision-making through real-time elemental mapping.
- [From Adsorption to Action: Characterizing PFAS Adsorption Mechanisms with QCM-D ](https://www.nanoscience.com/customer-stories/from-adsorption-to-action-characterizing-pfas-adsorption-mechanisms-with-qcm-d/): In the KORES (Karanikola Optimized Research for Environmental Sustainability) lab led by Dr. Vicky Karanikola, at the Department of Chemical &amp; Environmental Engineering at the University of Arizona, graduate student McKenna Dunmyer and her colleagues are advancing research on per- and polyfluoroalkyl substances (PFAS) by leveraging Quartz Crystal Microbalance with Dissipation (QCM-D) technology. This highly sensitive technique enables real-time observation of PFAS adsorption behavior on engineered sorbent materials, offering valuable insights into the mechanisms involved. The QCM-D’s unique data has been instrumental in revealing the kinetics of PFAS interactions with organosilane-functionalized silicon surfaces. The team’s research highlights the roles of electrostatic and hydrophobic forces in PFAS adsorption, providing a foundation for enhanced remediation methods to remove these persistent contaminants from water sources. 
- [Unlocking the Power of Energy Dispersive X-Ray Spectroscopy (EDS) with Scanning Electron Microscopy (SEM) ](https://www.nanoscience.com/blogs/unlocking-the-power-of-energy-dispersive-x-ray-spectroscopy-eds-with-scanning-electron-microscopy-sem/): The ability to precisely analyze a material&#039;s structure and composition at the microscopic scale is essential for advancing research and innovation. Scanning electron microscopy (SEM) has been a pivotal tool, providing high-resolution imaging of surface topography. Yet, imaging alone can only tell part of the story. To uncover the elemental makeup of these materials, scientists rely on energy dispersive X-ray spectroscopy (EDS), a powerful analytical technique integrated with SEM. EDS enables researchers to probe deeper, revealing not just how a material looks, but what it&#039;s made of. Now, with advancements in SEM technology—particularly the Phenom Desktop SEM—this combination of imaging and elemental analysis is reaching new levels of speed and accessibility. Let’s explore what EDS offers and how the Phenom Desktop SEM is pushing the boundaries of material characterization. 
- [Secondary Electrons in SEM: Unlocking Surface Insights at the Nanoscale ](https://www.nanoscience.com/blogs/secondary-electrons-in-sem-unlocking-surface-insights-at-the-nanoscale/): In scanning electron microscopy (SEM), secondary electrons (SE) play a pivotal role in revealing the surface details of materials at the nanoscale. Understanding what secondary electrons are, how they are generated, and what kind of information they provide is essential for anyone interested in material characterization, nanotechnology, or surface science. This blog will take a deep dive into secondary electrons and what we can learn from them in SEM imaging. 

## Pages
- [Field Service Engineer (AZ)](https://www.nanoscience.com/about-us/jobs/az-field-service-engineer/): Nanoscience Instruments (NSI) sells and services sophisticated scientific instrumentation, in the field of microscopy, including scanning electron microscopes (SEM), surface science systems, transmission electron microscopy (TEM) accessories, and electro-spinning/spraying equipment.
- [Order Management Manager (AZ)](https://www.nanoscience.com/about-us/jobs/order-management-manager-az/): Nanoscience Instruments specializes in the sale and servicing of advanced scientific instrumentation utilized by universities, research institutions, startups, government agencies, and military laboratories. Our diverse portfolio includes electron microscopes, scanning probe microscopes, optical microscopes, and material analysis systems. We foster an informal, yet professional environment supported by a team with strong engineering and scientific backgrounds.
- [Service Coordinator (AZ)](https://www.nanoscience.com/about-us/jobs/service-coordinator-az/): Nanoscience Instruments specializes in the sale and servicing of advanced scientific instrumentation utilized by universities, research institutions, startups, government agencies, and military laboratories. Our diverse portfolio includes electron microscopes, scanning probe microscopes, optical microscopes, and material analysis systems. We foster an informal, yet professional environment supported by a team with strong engineering and scientific backgrounds.
- [Preparing &#038; Characterizing Electrospinning Solutions](https://www.nanoscience.com/techniques/electrospinning/preparing-characterizing-electrospinning-solutions/): For infrequent users or researchers working with home-built units, electrospinning and electrospraying can appear to have difficulties with reproducibility. When processing parameters are all globally controlled, but batch-to-batch inconsistencies are still present, sample development can become a frustrating experience. However, electrospinning and electrospraying depend on both the processing parameters and the solution being processed. A fully characterized solution that is easily reproducible is crucial for preventing process instability and minimizing sample variability.
- [SenseAi AMA Series](https://www.nanoscience.com/senseai-ama-series/): We&#039;re excited to announce a series of online &#039;Ask me Anything (AMA)&#039; sessions for 2026. We&#039;ll cover a range of EM imaging subjects and techniques, all designed to educate but also to open up the floor to participants keen to discuss specific questions, pain points or advice. Professor Nigel Browning, Chair of Electron Microscopy at Liverpool University will host the sessions, and will be joined by some of the Worlds leading scientists from the world of EM. You can find the dates and sign up in advance below.
- [Support &#8211; 25](https://www.nanoscience.com/support-2/): For troubleshooting, training, and service related questions please register. Please have your equipment serial number and company name ready for registration, these will be required to be approved for the self service portal.
- [Field Service Engineer (VA)](https://www.nanoscience.com/about-us/jobs/field-service-engineer-alexandria-va/): At Nanoscience Instruments, we market, sell, and service sophisticated, mostly bench-top scientific instrumentation. Our products are utilized by universities, government labs, technology startups, and multinational corporations across the US and Canada. We enable innovation by providing complex instrumentation that facilitates scientists in processing and investigating molecular interactions down to the nanoparticle size.
- [Solutions for Cleanliness](https://www.nanoscience.com/solutions/solutions-for-cleanliness/): Proper assessment of part or surface cleanliness is critical for maintaining the health of mechanics, electronics, and people. While qualitative measurement methods can be adequate for certain applications, verifying technical cleanliness status requires quantitative data. This information can also be used to determine the efficacy of experimental cleaning strategies. Progress in this field can have direct impacts on standards of living, from daily-use product efficiency to surface sanitization and air quality.
- [SEM Video Gallery](https://www.nanoscience.com/sem-video-gallery/): Nanoscience Instruments combines expertise in microscopy and surface science instrumentation with real-world solutions. We partner with innovative instrument manufacturers around the world to help scientists and engineers solve complex problems leading to break-through innovations. Our team of scientists and engineers are passionate about solutions and connecting our customers with the right products and services to accomplish these goals.
- [Polymer Scientist (AZ)](https://www.nanoscience.com/about-us/jobs/polymer-chemist-az/): Nanoscience Analytical bridges the curiosity and technical depth of academia with the pace and practical problem solving of industry and startup environments. Our scientists develop new methods, approaches, and applications in polymeric materials science while working directly with customers across diverse industries, making every project an opportunity to learn something new and translate science into useful outcomes.
- [Electrospinning Optical Gallery](https://www.nanoscience.com/electrospinning-optical-gallery/): Electrospun nanofibrous scaffolding sample for wound dressing applications. It is made out of a natural based protein able to biomimic the extracellular matrix. These types of samples can be made with natural polymers like collagen, gelatin, chitosan and soy based materials. Researchers have also used FDA approved synthetic polymers like polycaprolactone, polylactic acid, and poly(lactic-co-glycolic acid).
- [SEM Gallery &#8211; Redez](https://www.nanoscience.com/sem-gallery-redez/): Nanoscience Instruments combines expertise in microscopy and surface science instrumentation with real-world solutions. We partner with innovative instrument manufacturers around the world to help scientists and engineers solve complex problems leading to break-through innovations. Our team of scientists and engineers are passionate about solutions and connecting our customers with the right products and services to accomplish these goals.
- [Electrospinning Video Gallery](https://www.nanoscience.com/electrospinning-video-gallery/): Electrospinning is a voltage driven process where fibers are generated, typically out of a polymer solution. This video shows the solution dripping from a capillary blunt needle until the voltage is turned ON. Once the voltage is turned ON, charges accumulate on the surface of the solution and the solution is ejected when the surface tension is overcome. The polymer solution is then ejected, solvent evaporates through whipping and bending, and the fibers are generated when the polymer solidifies.
- [Our Partners](https://www.nanoscience.com/about-us/our-partners/): Nanoscience Instruments combines expertise in microscopy and surface science instrumentation with real-world solutions. We partner with innovative instrument manufacturers around the world to help scientists and engineers solve complex problems leading to break-through innovations.
- [Electrospun Sample Request](https://www.nanoscience.com/electrospun-sample-request/): To enable you to test out the electrospinning technique for your application, our experts will fabricate samples for you. Please expect an email or phone call within the next business day.  Thank you for choosing Nanoscience Instruments.
- [Electrospinning Image Gallery](https://www.nanoscience.com/electrospinning-image-gallery/): Electron micrograph of electrosprayed polycaprolactone (PCL) microparticles made with a Fluidnatek LE-50. These particles were made with a high boiling point and low vapor pressure solvent allowing them to obtain a smooth and rounded morphology. After collecting onto a liquid reservoir, the media was evaporated, and the PCL particles agglomerated for future experiments
- [Solutions for Pharmaceuticals](https://www.nanoscience.com/solutions/solutions-for-pharmaceuticals/): In addition to the value contributed to human health and quality of life, the global market for pharmaceuticals was valued at close to $1.5 trillion in 2022. Empowering research and development in this field with precise and powerful instrumentation is essential for the discovery of novel drugs and optimization of current ones. From initial compounding to purification, storage, and delivery, there are many steps of the production process that could benefit from focused experimentation.
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- [Critical Micelle Concentration (CMC)](https://www.nanoscience.com/techniques/tensiometry/critical-micelle-concentration-cmc/): toolsetCommonEs.fontToHead()
- [Solutions for Semiconductor Research &#038; Development](https://www.nanoscience.com/solutions/solutions-for-semiconductor-research-development/): Heterogeneous integration is becoming increasingly important for achieving system-level scaling and overall package miniaturization. Developing reliable advanced IC packaging, as well as overcoming the many challenges in this space, depends upon leveraging insights gained from high-resolution imaging and interfacial analysis to select novel materials and improve manufacturing processes.
- [Surface &#038; Interfacial Tension](https://www.nanoscience.com/techniques/tensiometry/surface-and-interfacial-tension/): toolsetCommonEs.fontToHead()
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- [SEM Image Gallery](https://www.nanoscience.com/sem-image-gallery/): Nanoscience Instruments combines expertise in microscopy and surface science instrumentation with real-world solutions. We partner with innovative instrument manufacturers around the world to help scientists and engineers solve complex problems leading to break-through innovations. Our team of scientists and engineers are passionate about solutions and connecting our customers with the right products and services to accomplish these goals.
- [Tensiometry / Goniometry](https://www.nanoscience.com/techniques/tensiometry/): toolsetCommonEs.fontToHead()
- [Scanning Transmission Electron Microscopy](https://www.nanoscience.com/techniques/scanning-transmission-electron-microscopy/): Scanning transmission electron microscopy (STEM) is an advanced imaging technique that is used to visualize the structure and composition of materials at nanometer to sub-atomic length scales. It provides high-resolution images and spectroscopic data by scanning a focused electron beam across a very thin sample and collecting various signals in parallel. The most common signals acquired in STEM are bright field (BF), annular dark field (ADF), and high-angle annular dark field (HAADF) images. The technique is commonly paired with energy-dispersive X-ray spectroscopy (EDS) and electron energy-loss spectroscopy (EELS) to provide correlative spectral maps of elemental composition and electronic structure.&nbsp;
- [Needle-Based Vs Needle-Less Electrospinning](https://www.nanoscience.com/techniques/electrospinning/needle-based-vs-needle-less-electrospinning/): There are two distinctive ways fibers can be made using the electrospinning technique: needle-based electrospinning, or needle-less electrospinning. The ways in which the two setups differ could make one more suitable for a particular application than the other, but both are easy methods for fabricating functional nanomaterials. The diagram below highlights the flexibility of the electrospinning technique and the many different setups that are possible with both needle-based and needle-less electrospinning systems.
- [Electrospinning](https://www.nanoscience.com/techniques/electrospinning/): Electrospinning is a voltage-driven, fabrication process governed by a specific electrohydrodynamic phenomenon where small fibers are yielded from a polymer solution. The most basic setup for this technique involves a solution contained in a reservoir — typically a syringe — tipped with a blunt needle (at least for needle-based electrospinning), a pump, a high voltage power source, and a collector.
- [Electrospraying](https://www.nanoscience.com/techniques/electrospraying/): Electrospraying is a voltage-driven process governed by the electrohydrodynamic phenomena where particles are made from a polymer solution. The particle diameter generated with this technique typically ranges between tens of nanometers to a few micrometers (ex. 50 nm to 50 µm). The most basic setup for this technique involves a solution contained in a reservoir (typically a syringe) and tipped with a blunt needle (for needle-based electrospraying), a pump, a high voltage power source and a collector. 
- [Phenom Desktop SEM Pricing](https://www.nanoscience.com/phenom-desktop-sem-pricing/): Phenom Desktop SEMs deliver a best-in-class performance for high-resolution imaging and elemental analysis. The fully integrated platform leverages resilient hardware and intuitive software to achieve superb image quality and speed-to-data at a low cost of ownership. An easily navigable user interface makes accessing all microscope functions and optimizing imaging parameters a breeze for users of all skill levels. Images are less than 60 seconds away from loading the sample thanks to the fastest vent/load cycle and high-sensitivity detector, standard to all Phenoms.
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- [Home](https://www.nanoscience.com/): Nanoscience Instruments combines expertise in microscopy and surface science instrumentation with real-world solutions. We partner with innovative instrument manufacturers around the world to help scientists and engineers solve complex problems leading to break-through innovations.
- [Transmission Electron Microscopy](https://www.nanoscience.com/techniques/transmission-electron-microscopy/): Transmission electron microscopy (TEM) is an analytical technique used to visualize the smallest structures in matter. Unlike optical microscopes, which rely on light in the visible spectrum, TEM can reveal stunning detail at the atomic scale by magnifying nanometer structures up to 50 million times. This is because electrons can have a significantly shorter wavelength (about 100,000 times smaller) than that of visible light when accelerated through a strong electromagnetic field, thus increasing the microscope resolution by several orders of magnitude.
- [Solutions for Chemical Engineering](https://www.nanoscience.com/solutions/solutions-for-chemical-engineering/): Nanoscience Instruments, a trusted supplier of innovative scientific instrumentation, has curated solutions that support scientists in pursuit of advancements in their respective fields of chemical engineering. From generating novel nanomaterials to characterizing their properties and probing their interactions at the molecular level, our solutions enable unique experiments with powerful results.
- [Empowering Battery Research](https://www.nanoscience.com/solutions/empowering-battery-research/): Battery technology continues to experience massive growth and innovation that is driven by the electrification of everything. Some of the biggest challenges faced in this industry are designing batteries with higher energy and power density, reducing charge times, extending battery lifetimes, and reducing the cost and environmental impact of manufacturing.
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- [Langmuir Films](https://www.nanoscience.com/techniques/langmuir-films/): Langmuir Films are thin organic films of a thickness of just one molecule and are the source of high expectations. As useful components in many practical and commercial applications such as sensors, detectors, displays and electronic circuit components. With both the possibility to synthesize custom organic molecules and sophisticated thin film deposition technology it is possible to create electrically, optically and biologically active components on a nanometer scale.
- [Quartz Crystal Microbalance (QCM)](https://www.nanoscience.com/techniques/quartz-crystal-microbalance/): Quartz Crystal Microbalance with Dissipation Monitoring (QCM-D) is a powerful analytical technique used to study nanoscale surface interactions in real-time and label-free. By detecting mass shifts as molecules attach to or detach from the sensor surface, QCM-D tracks subtle changes in molecular interactions. It simultaneously measures energy dissipation, distinguishing between soft and rigid materials based on their viscoelastic properties. The technique works by applying an alternating current (AC) to a piezoelectric quartz crystal disc, inducing oscillations at a resonant frequency. As mass accumulates or is removed from the surface, the crystal’s resonant frequency and energy dissipation change. These combined measurements make QCM-D an essential tool for studying complex systems such as proteins, polymers, and biomolecular assemblies.
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- [Company History](https://www.nanoscience.com/about-us/company-history/): Nanoscience Instruments was founded in 2002 by a team of energetic and experienced scientists with a mission to bring nanoscience and nanotechnology to educators and researchers in the advent of this growing field of nanotechnology. New technologies like atomic force microscopy were being leveraged for ground-breaking insights into the nanoscale world. The team used their expertise to guide and support newcomers to this industry and developed strong relationships across many fields of “nano” from education and academic research to industrial R&amp;D and quality assurance.
- [Nanoindentation Methods](https://www.nanoscience.com/techniques/nanoindentation/nanoindentation-methods/): Mechanical testing is used to determine properties such as hardness, modulus, fracture toughness or yield strength. Bulk samples typically are examined using uniaxial compression and tensile testing to acquire elastic modulus data which requires days of sample preparation and testing. Hardness test methods use an indenter probe that is displaced into a surface under a specific load. In traditional testing, the size or depth of indentation is measured to determine hardness leading to user bias in the data. Microhardness testing is an industry standard for quality and process control for hardness data. Microhardness testing, with applied loads under 10 N, is typically used for smaller samples, thin specimens, plated surfaces or coatings.
- [Mechanical Properties](https://www.nanoscience.com/techniques/nanoindentation/mechanical-properties/): Measuring and understanding the mechanical response is critical for material research, product development, and process control. The mechanical response of these materials is dependent on the application scenarios as well as material chemistry. The main parameters that are considered to measure these mechanical properties are load (P), loading rate or strain rate (Ṗ/ἐ), time of loading (t).
- [Nanoindentation](https://www.nanoscience.com/techniques/nanoindentation/): The nanoindentation experiments can be performed in several modes depending on the material properties desired. The ISO method is used to check the calibrations of the system while continuous stiffness measurements provide the depth-dependent properties. The viscoelastic response can be characterized by measuring the complex modulus of the material while performing frequency sweeps over the desired range. The fatigue testing can be performed in the cyclic indentation mode to measure the fatigue/fracture life of materials.
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- [Scanning Tunneling Microscopy](https://www.nanoscience.com/techniques/scanning-tunneling-microscopy/): The development of the family of scanning probe microscopes started with the original invention of the STM in 1981. Gerd Binnig and Heinrich Rohrer developed the first working STM while working at IBM Zurich Research Laboratories in Switzerland. This instrument would later win Binnig and Rohrer the Nobel prize in physics in 1986.
- [Ion Milling](https://www.nanoscience.com/techniques/ion-milling/): Ion polishing and milling is a materials processing technique used to remove material from a sample surface by bombarding it with a beam of charged nuclei. The process relies on sputtering, in which energized ions physically eject other atoms and molecules from the sample surface through momentum transfer. Ion milling is commonly used in materials science and engineering for applications such as cross-sectioning samples, thinning samples for electron transparency, and removing layers for deeper analysis. The technique is an important tool for preparing specimens and revealing internal structures and compositions for investigation under electron microscopes.
- [Scanning Electron Microscopy](https://www.nanoscience.com/techniques/scanning-electron-microscopy/): Scanning electron microscopy is a highly versatile technique used to obtain high-resolution images and detailed surface information of samples. It is a type of electron microscopy that uses a focused beam of electrons to scan the surface of a specimen and generate images at a much greater resolution compared to optical microscopy. The resolution of SEM instruments can range from &lt; 1 nanometer up to several nanometers.
- [About Us](https://www.nanoscience.com/about-us/): Nanoscience Instruments combines expertise in microscopy and surface science instrumentation with real-world solutions. We partner with innovative instrument manufacturers around the world to help scientists and engineers solve complex problems leading to break-through innovations. Our team of scientists and engineers are passionate about solutions and connecting our customers with the right products and services to accomplish these goals.
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- [Protected: MP-SPR Navi](https://www.nanoscience.com/products/mp-spr-navi/): BioNavis Surface Plasmon Resonance (SPR) systems deliver highly sensitive, real-time, label-free analysis of molecular interactions and thin-film properties for research across life sciences and materials science. Built on the advanced Multi-Parametric Surface Plasmon Resonance (MP-SPR) platform, BioNavis instruments record the complete resonance curve over multiple wavelengths, expanding on traditional SPR capabilities that only monitors a single parameter i.e. resonance peak minimum.
- [Attension® Sigma CMC](https://www.nanoscience.com/products/attension-tensiometers/force-tensiometers/attension-sigma-cmc/): The highly sensitive instruments offer high precision surface and interfacial tension measurements, fully automated critical micelle concentration (CMC) determination and measurement of dynamic contact angle, surface free energy, powder wettability, sedimentation, and density.
- [Attension® Sigma Peak](https://www.nanoscience.com/products/attension-tensiometers/force-tensiometers/attension-sigma-peak/): The highly sensitive instruments offer high precision surface and interfacial tension measurements, fully automated critical micelle concentration (CMC) determination and measurement of dynamic contact angle, surface free energy, powder wettability, sedimentation, and density.
- [Attension® Sigma Solo Transformer Oil](https://www.nanoscience.com/products/attension-tensiometers/force-tensiometers/attension-sigma-solo-transformer-oil/): Sigma Transformer Oil is designed for oil-water interfacial tension measurements in accordance to the ASTM D971 and IEC 62961 standards. The embedded software will guide the user throughout the measurement and make sure the measurement is done automatically and in compliance with the ASTM D971 standard.
- [Attension® Sigma Solo](https://www.nanoscience.com/products/attension-tensiometers/force-tensiometers/attension-sigma-solo/): The open design and convenient control keyboard operations make the Sigma Solo extremely easy to use. Results are displayed on a large integrated digital screen. The instrument comes equipped with data software and can be connected to an external computer for additional data storage and simple reporting.
- [Attension® Sigma Base](https://www.nanoscience.com/products/attension-tensiometers/force-tensiometers/attension-sigma-base/): Sigma Base is a simple and robust digital force tensiometer for accurate measurement of surface and interfacial tension (Platinum Du Noüy ring, Platinum Wilhelmy Plate), and density. Manual measurement of Critical Micelle Concentration (CMC) can also be conducted.
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- [QSoft Software](https://www.nanoscience.com/products/qsense-quartz-crystal-microbalance/software/qsoft-software/): QSense DFind is the reliable and easy-to-use analysis software for experiments performed on QSense Explorer, Analyzer, Pro, and Omni systems. It helps you to quickly and simply extract the information you are looking for, such as mass, thickness, viscoelasticity, and adsorption or desorption rates.
- [QSoft Omni](https://www.nanoscience.com/products/qsense-quartz-crystal-microbalance/software/qsoft-omni/): QSense DFind is the reliable and easy-to-use analysis software for experiments performed on QSense Explorer, Analyzer, Pro, and Omni systems. It helps you to quickly and simply extract the information you are looking for, such as mass, thickness, viscoelasticity, and adsorption or desorption rates.
- [QSense™ Software Packages](https://www.nanoscience.com/products/qsense-quartz-crystal-microbalance/software/): QSense QCM-D (quartz crystal microbalance with dissipation) systems enable real time monitoring of nanoscale molecular interactions and structural changes at surfaces and interfaces.
- [KSV NIMA Roll-to-Roll Langmuir Blodgett Trough](https://www.nanoscience.com/products/ksv-nima-langmuir-blodgett-troughs/roll-to-roll-lb-trough/): KSV NIMA Langmuir Troughs are the ultimate tools for effective thin layer coatings and studies. Used for creating, modifying, and studying floating Langmuir films.
- [Protected: ParticleX Cleanliness](https://www.nanoscience.com/products/phenom-desktop-sem/software-automation-packages/particlex/particlex-technical-cleanliness-tc-copy/): The ParticleX Cleanliness solution allows manufacturers and suppliers the ability to measure the size, shape, and elemental composition of each particle.
- [SenseAI Software](https://www.nanoscience.com/products/senseai-software/): This content is password protected. To view it please enter your password below:
- [Polymer Shaping Systems](https://www.nanoscience.com/products/polymer-compounding-shaping/polymer-shaping-systems/): Micro-compounders are widely used in research and development for small-scale polymer processing. To further process and shape extruded polymers, various polymer shaping systems are available, ensuring precise control over strand formation, cooling, and granulation. These systems are designed to handle the fragile nature of newly extruded polymer strands while preparing them for further analysis, secondary processing, or upscaling. 
- [Micro-Compounding Systems](https://www.nanoscience.com/products/polymer-compounding-shaping/micro-compounding-systems/): Micro-compounders are specialized miniaturized extruders used in small scale polymer processing that involves mixing, blending and modification of polymeric materials. This enables researchers and manufacturers to develop and test polymer formulations in small batches, typically ranging from a few grams to a few hundred grams. 
- [Polymer Compounding &#038; Shaping](https://www.nanoscience.com/products/polymer-compounding-shaping/): The CB Pro unit is designed to guide polymer strands directly from a small extruder or compounder, seamlessly integrating with Xplore micro-compounders for efficient processing.
- [Phenom SEM Software &#038; Automation Packages](https://www.nanoscience.com/products/phenom-desktop-sem/software-automation-packages/): Streamline your workflows and unlock the full potential of your Phenom Desktop SEM with tailored software and automation solutions. Designed to enhance productivity, these tools provide advanced image and EDS analysis options, automated data collection, and seamless data management for a wide range of applications. Each solution empowers users of any experience level to achieve consistent, high-quality results with ease. The result: reduced operational costs, actionable insights, and standardized protocols tailored to maximize the capabilities of your Phenom Desktop SEM.
- [Avizo Trueput](https://www.nanoscience.com/products/phenom-desktop-sem/software-automation-packages/avizo-trueput/): Transform your Phenom Desktop or Thermo Scientific SEM into a dedicated battery quality analysis solution with Avizo Trueput Software. Designed to streamline battery inspection on the production floor, Avizo Trueput automates image analysis, converting SEM image datasets into clear, reproducible pass/fail reports. This powerful tool enables QA/QC teams to maximize efficiency and maintain quality standards, freeing up valuable engineering time for more critical tasks.
- [Phenom Pharos Desktop STEM](https://www.nanoscience.com/products/phenom-desktop-sem/pharos-desktop-stem/): The STEM Sample Holder adds a new dimension of imaging capabilities to the Phenom Pharos Desktop SEM, making application diversity even more accessible and expanding advanced imaging to all levels of microscopy expertise.
- [MAPS Software for Phenoms](https://www.nanoscience.com/products/phenom-desktop-sem/software-automation-packages/maps/): MAPS software is a transformative tool for Phenom Desktop Scanning Electron Microscopes (SEMs), designed to boost both the efficiency and depth of your analytical workflows. MAPS features seamless image stitching – for both SEM images and EDS maps – to characterize vast sample areas.
- [Electrospinning Collectors](https://www.nanoscience.com/products/electrospinning-products/electrospinning-collectors/): A critical component of the electrospinning or electrospraying setup is the collector, as it is where the sample is deposited. For electrospinning, the type of collector used during processing has a direct impact on the alignment of the fibers as well as the size and shape of the final electrospun sample. For electrospraying, the type of collector can prevent particle agglomeration and allow easier removal of particles post-processing.
- [Electrospinning Emitters](https://www.nanoscience.com/products/electrospinning-products/electrospinning-emitters/): There are several types of emitters, also referred to as nozzles or spinnerets, used for processing electrospun fibers and electrosprayed particles, or blow-spun or sprayed materials. The type of emitter used for an electrospinning or electrospraying process depends on the desired morphology and composition of the final product, based on application needs.
- [ChemiSEM &#038; ChemiPhase](https://www.nanoscience.com/products/phenom-desktop-sem/software-automation-packages/chemisem-chemiphase/): ChemiSEM is a software capability that merges high resolution SEM imaging with real time elemental analysis EDS. This complete integration means that as you capture detailed SEM images, you simultaneously gain instant access to the elemental composition of your sample. Switching between different software interfaces is unnecessary – ChemiSEM brings everything together in one intuitive interface with a single click. With Phenom Desktop SEMs, the X-ray signals generated by the sample interacting with the electron beam are continuously collected and overlayed with the backscattered electron signals, creating a color-coded overlay of elemental information that provides clear, immediate visualizations of the chemical makeup of your samples.
- [SEMPREP SMART](https://www.nanoscience.com/products/broad-ion-beam-polishers/semprep-smart/): SEMPrep SMART is a state-of-the-art multifunctional ion milling system for slope cutting and damage-free surface polishing that is vital for SEM and EBSD sample preparation.
- [Fluidnatek® LE-500 BioDevice](https://www.nanoscience.com/products/electrospinning-products/fluidnatek-le-500-biodevice/): For scientists and engineers needing pre-production volumes and production-quality materials. The LE-500 can be used in advanced development projects, beta-release, and other pre-market introduction activities.
- [Fluidnatek® Dry Heating Unit (DHU)](https://www.nanoscience.com/products/electrospinning-products/fluidnatek-dry-heating-unit-dhu/): An intermediate temperature and humidity control component for electrospinning and electrospraying that allows consistent, quality nanoscale materials for advanced research to product development scale production. An ideal unit when processing solutions requiring low humidity and/or increased temperature. Used in locations where humidity is too high throughout the year.
- [Fluidnatek® Environmental Control Unit (ECU)](https://www.nanoscience.com/products/electrospinning-products/fluidnatek-environmental-control-unit-ecu/): An essential electrospinning and electrospraying complementary component for consistent, quality nanoscale materials at any scale of production.
- [Nebula Powder Disperser](https://www.nanoscience.com/products/phenom-desktop-sem/nebula-powder-disperser/): The Nebula Powder Disperser is an instrument designed to aid in the preparation of powder samples for analysis in a scanning electron microscope (SEM). It provides a standard method for achieving uniform, even dispersion of dry powders onto aluminum sample stubs. 
- [Naiad Automated Graphene Liquid Cells](https://www.nanoscience.com/products/naiad-automated-graphene-liquid-cells/): The Naiad is VitroTEM’s benchtop device for automated graphene liquid cell fabrication. Naiad fully automates the preparation and handling of graphene, delivering efficient and reliable sample production.
- [Desktop STEM Detector](https://www.nanoscience.com/products/phenom-desktop-sem/phenom-pharos-desktop-sem/stem-sample-holder/): The Phenom STEM (scanning transmission electron microscopy) detector enables transmission imaging for the Phenom Pharos. STEM imaging offers increased visibility of sample morphology and reveals subsurface structural details at higher resolutions than conventional SEM.&nbsp;
- [KSV NIMA Surface Potential Sensor](https://www.nanoscience.com/products/ksv-nima-langmuir-blodgett-troughs/spot-surface-potential-sensor/): The KSV NIMA Surface Potential Sensor (SPOT) is used for determining molecular orientation changes in Langmuir films.
- [KSV NIMA MicroBAM](https://www.nanoscience.com/products/ksv-nima-langmuir-blodgett-troughs/microbam/): MicroBAM (Brewster Angle Microscope) enables visualization of monolayers, typically at the air-water interface in a Langmuir Trough.
- [QSense™ Modules](https://www.nanoscience.com/products/qsense-quartz-crystal-microbalance/qsense-modules/): This content is password protected. To view it please enter your password below:
- [QSense™ High Temperature Chamber](https://www.nanoscience.com/products/qsense-quartz-crystal-microbalance/qsense-high-temperature-chamber/): QSense provides a unique solution for you to understand the surface interactions of oil components, additives and other relevant chemicals in real-time.
- [DFind Data Analysis Software](https://www.nanoscience.com/products/qsense-quartz-crystal-microbalance/software/dfind-data-analysis-software/): QSense DFind is the reliable and easy-to-use analysis software for experiments performed on QSense Explorer, Analyzer, Pro, and Omni systems. It helps you to quickly and simply extract the information you are looking for, such as mass, thickness, viscoelasticity, and adsorption or desorption rates.
- [GentleMill](https://www.nanoscience.com/products/broad-ion-beam-polishers/gentle-mill/): The Gentle Mill is designed for the final polishing and cleaning of TEM samples and features the best-in-class patented low-energy ion source.
- [Unimill](https://www.nanoscience.com/products/broad-ion-beam-polishers/unimill/): The UniMill is a fully automated ion beam thinning system for TEM sample preparation with market leading thinning rates. The instrument enables both rapid milling and final polishing and cleaning.
- [Python-Based SEM Automation](https://www.nanoscience.com/products/phenom-desktop-sem/software-automation-packages/python-automation/): Phenom Desktop SEMs benefit from Python compatibility, a feature that enables users to activate coded scripts that control imaging workflows and data collection procedures.
- [QSense™ Omni](https://www.nanoscience.com/products/qsense-quartz-crystal-microbalance/qsense-omni/): QSense Omni is the new, cutting-edge instrument from the pioneers of QCM-D. Based on established technology, which has supported a deeper understanding of surface and interface interactions for decades, QSense Omni gives you sharper QCM-D data and a smooth journey in the lab.
- [Phenom P-Series Sample Holders](https://www.nanoscience.com/products/phenom-desktop-sem/p-series-sample-holders/): The Phenom P-Series lineup of desktop SEMs is comprised of the Pharos, Pro/ProX, and Pure systems, each compatible with variety of sample holders for highly specialized applications.
- [Electron Detectors](https://www.nanoscience.com/products/phenom-desktop-sem/electron-detectors/): The backscattered electron detector (BSD) and secondary electron detector (SED) are responsible for detecting electrons resulting from interactions between the electron beam and sample surface. The two detectors collect different signals that convey varying information about atomic numbers and surface topography.
- [Phenom XL Sample Stages](https://www.nanoscience.com/products/phenom-desktop-sem/xl-sample-stages/): The Phenom XL supports several multi-sample stages and stage inserts for highly specialized applications.
- [ParticleX](https://www.nanoscience.com/products/phenom-desktop-sem/software-automation-packages/particlex/): Many industries rely on SEM and EDS data to improve the quality and reliability of their products. ParticleX software equips the Phenom Desktop SEM to deliver end-to-end data collection and analysis for a variety of applications, without the requirement of a skilled operator. By automating both SEM and EDS data collection and analysis, the size, shape, and elemental composition of thousands of features can be accurately detected and quantified for multiple samples at the push of a button. Several ready-to-use packages are available, or users can create their own workflow using an intuitive user interface.
- [ProSuite Image Analysis Software](https://www.nanoscience.com/products/phenom-desktop-sem/software-automation-packages/prosuite/): Image analysis software can extract actionable data about the size and shape of features in an SEM image. Developed specifically for the Phenom, it increases data throughput and eliminates user bias that can skew manual measurements.
- [ParticleX Gunshot Residue (GSR)](https://www.nanoscience.com/products/phenom-desktop-sem/software-automation-packages/particlex/gunshot-residue/): Perception GSR, is the first dedicated solution that can run automated GSR analysis. Quickly obtain reliable and accurate results from even miniscule pieces of evidence with an included calibration sample.
- [ParticleX Battery](https://www.nanoscience.com/products/phenom-desktop-sem/software-automation-packages/particlex/battery/): ParticleX Battery serves as a flexible solution that allows for precise in-house analysis of battery materials like the NCM powder. It enables expedited analysis, authentication, and categorization of materials, providing production support with swift, accurate, and reliable data.
- [ParticleX Steel](https://www.nanoscience.com/products/phenom-desktop-sem/software-automation-packages/particlex/steel/): The Phenom ParticleX Steel Desktop SEM solution is a versatile and easy-to-use instrument for automated inclusion analysis and reporting. It adds fast and accurate automated inclusion analysis software to the world’s bestselling desktop SEM.
- [ParticleX Technical Cleanliness (TC)](https://www.nanoscience.com/products/phenom-desktop-sem/software-automation-packages/particlex/technical-cleanliness/): The ParticleX Technical Cleanliness (TC) solution allows manufacturers and suppliers the ability to measure the size, shape, and elemental composition of each particle.
- [ParticleX Additive Manufacturing (AM)](https://www.nanoscience.com/products/phenom-desktop-sem/software-automation-packages/particlex/additive-manufacturing/): Quality additive manufacturing processes require validation of feedstock powder properties. While scanning electron microscopy (SEM) and energy-dispersive X-ray spectroscopy (EDS) are well suited to this task, implementing this technique with high throughput and accuracy can be challenging in a manufacturing environment.
- [Electrospinners &#038; Electrosprayers](https://www.nanoscience.com/products/electrospinning-products/): The Spinbox® and Fluidnatek® by Bioinicia family of instruments are designed to maximize control over electrospinning and electrospraying processes, enabling the reproducible fabrication of perfect nanofibers and nanoparticles.
- [Attension® Tensiometers](https://www.nanoscience.com/products/attension-tensiometers/): Biolin Scientific’s range of Attension tensiometers spans both optical and force characterization techniques, offering maximum versatility for studying surfaces and interfaces.
- [Vitrojet Cryo-EM Sample Preparation](https://www.nanoscience.com/products/vitrojet/): The VitroJet™ is a next generation cryo-EM sample vitrification robot designed in part to minimize manual manipulation throughout the cryo-EM grid preparation workflow while improving sample quality and consistency.
- [Interfacial Shear Rheometer Flip](https://www.nanoscience.com/products/ksv-nima-langmuir-blodgett-troughs/interfacial-shear-rheometer-flip/): The KSV NIMA ISR Flip is an Interfacial Shear Rheometer that enables highly sensitive measurements of interfacial viscoelasticity and stability at air-liquid and liquid-liquid interfaces.
- [Phenom SEM Electron Sources](https://www.nanoscience.com/products/phenom-desktop-sem/electron-sources/): Phenom Desktop SEMs are equipped with two advanced electron source options, each tailored to specific imaging needs. The Cerium Hexaboride (CeB6) crystal is a thermionic electron source, while the Schottky Field Emission Gun (FEG) relies on electron tunneling.
- [Energy Dispersive X-ray Spectroscopy (EDS)](https://www.nanoscience.com/products/phenom-desktop-sem/energy-dispersive-x-ray-spectroscopy/): Energy dispersive X-ray spectroscopy (EDS or EDX) provides elemental composition information by analyzing the X-rays released by a sample when hit by the electron beam. This is a fast, accurate and non-destructive method for identifying compounds on a micron-scale.
- [Fluidnatek® LE-100 Biotubing](https://www.nanoscience.com/products/electrospinning-products/le-100-biotubing/): The Fluidnatek LE-100 BioTubing is the equipment of choice for GMP production of high-value samples and the ideal electrospinning system for biomedical companies that need to coat stents, or fabricate vascular grafts, heart valves, and other tubular structures in an environment that meets standards for an ISO-7 environment, cGMP, or ISO-13485 certification.
- [Sputter Coaters](https://www.nanoscience.com/products/sputter-coaters/): Sputter coating is a process used to deposit a thin layer of material onto a substrate. In the case of scanning electron microscopy (SEM), this technique is used with metals such as gold or platinum to prepare samples for analysis, offering a range of advantages in improving conductivity, reducing electric charging effects, and even bolstering the level of structural protection against the electron beam.
- [Broad Ion Beam Polishers](https://www.nanoscience.com/products/broad-ion-beam-polishers/): Broad ion beam polishing is an essential part of the sample preparation process for electron microscopy analysis. This versatile method can remove surface contamination, planarize mechanically cross-sectioned samples, or thin and polish electron-transparent lamellae.
- [Phenom Pharos Desktop SEM](https://www.nanoscience.com/products/phenom-desktop-sem/phenom-pharos-desktop-sem/): The Phenom Pharos uses a field emission gun (FEG) as its source of electrons for applications that demand the highest resolution. Benefitting from a broad accelerating voltage range of 1-20 kV, the Pharos is capable of accommodating a variety of insulating and beam-sensitive samples with low kV imaging, an ability enhanced further by a temperature controlled sample holder, among other compatible holders.
- [Phenom Pure Desktop SEM](https://www.nanoscience.com/products/phenom-desktop-sem/phenom-pure-tabletop-sem/): The Phenom Pure G6 is an entry-level desktop SEM that provides a straightforward imaging solution perfect for teaching environments or basic R&amp;D applications. The power and innovative design of all Phenom systems are distilled into the perfect imaging platform, offering the best value of any SEM on the market. A high-resolution, color optical camera is included for easy navigation.
- [Phenom Pro/ProX Desktop SEM](https://www.nanoscience.com/products/phenom-desktop-sem/phenom-pro-prox-desktop-sem/): The Phenom Pro and ProX desktop SEMs are high-performance SEMs for the ultimate all-in-one imaging and X-ray analysis systems. A unique and powerful core architecture combines with a host of hardware and software features to provide the most complete desktop SEM solution on the market. Phenom SEMs are equipped with a high brightness Cerium Hexaboride (CeB6) source, allowing for better image resolution through the range of accelerating voltages and a longer source lifetime compared to tungsten sources.
- [Phenom XL Desktop SEM](https://www.nanoscience.com/products/phenom-desktop-sem/phenom-xl-desktop-sem/): The Phenom XL G2 desktop scanning electron microscope pushes the boundaries of desktop electron microscope with unprecedented opportunity for automation. Combining the proven ease of use and fast workflow of the Phenom series with the largest chamber and sample stage (100×100 mm2) of any desktop SEM results in a powerful tool for high-throughput analysis.
- [Phenom Desktop Scanning Electron Microscopes](https://www.nanoscience.com/products/phenom-desktop-sem/): Desktop SEMs, also called tabletop or benchtop SEMs, retain much of the power and capabilities of floor systems while also introducing a versatility of their own, fitting more easily into lab spaces and providing a suite of specialized software analysis tools.
- [KSV NIMA Langmuir-Blodgett Trough](https://www.nanoscience.com/products/ksv-nima-langmuir-blodgett-troughs/ksv-nima-langmuir-blodgett-trough/): KSV NIMA Langmuir-Blodgett Deposition Troughs (LB Troughs) have the same capabilities as KSV NIMA Langmuir Troughs as they also enable Langmuir film fabrication and study.
- [KSV NIMA Langmuir Trough](https://www.nanoscience.com/products/ksv-nima-langmuir-blodgett-troughs/ksv-nima-langmuir-trough/): KSV NIMA Langmuir Troughs are the ultimate tools for effective thin layer coatings and studies. Used for creating, modifying, and studying floating Langmuir films.
- [KSV NIMA Langmuir-Blodgett Troughs](https://www.nanoscience.com/products/ksv-nima-langmuir-blodgett-troughs/): The KSV NIMA Langmuir &amp; Langmuir-Blodgett (LB) troughs are top-of-the-line instruments used for creating thin film coatings with controlled packing density.
- [Fluidnatek® HT](https://www.nanoscience.com/products/electrospinning-products/high-throughput/): The Fluidnatek HT Industrial Electrospinning Machine is the ideal industrial equipment when large scale production and sample reproducibility are needed. This industrial electrospinning line capitalizes on the know-how and experience in the field of materials processing by Bioinicia.
- [Fluidnatek® LE-500](https://www.nanoscience.com/products/electrospinning-products/le-500/): For scientists and engineers needing pre-production volumes and production-quality materials. The LE-500 can be used in advanced development projects, beta-release, and other pre-market introduction activities.
- [Fluidnatek® LE-100](https://www.nanoscience.com/products/electrospinning-products/le-100/): The ideal choice for scientists and engineers working on advanced development projects, where maximum experimental capabilities, tighter process control, and larger sample sizes are key.
- [Fluidnatek® LE-50 ProSterile](https://www.nanoscience.com/products/electrospinning-products/le-50-prosterile/): Ideal for biomedical companies requiring aseptic sample development for medical products under ISO-5 environment, cGMP, and ISO-13485 certification standards. The Fluidnatek LE-50 ProSterile is the instrument of choice for in-line aseptic electrospun bioprocesses, and medical device manufacturing of sterile products.
- [Fluidnatek® LE-50 G2](https://www.nanoscience.com/products/electrospinning-products/le-50/): Ideal for proof-of-concept and feasibility developing new materials and formulations. The Fluidnatek LE-50 electrospinning machine combines the compact, lightweight characteristics of the Spinbox with the features of an advanced research station.
- [Spinbox®](https://www.nanoscience.com/products/electrospinning-products/spinbox/): Ideal for proof-of-concept of new materials and formulations. Its wide range of capabilities and exceptional reliability allows scientists to efficiently prototype and optimize their concepts.
- [QSense™ Initiator](https://www.nanoscience.com/products/qsense-quartz-crystal-microbalance/qsense-initiator/): QSense Initiator has a robust design and focuses on the fundamental functions and qualities of QCM-D analysis, producing data with superior accuracy.
- [QSense™ Explorer](https://www.nanoscience.com/products/qsense-quartz-crystal-microbalance/qsense-explorer/): Thanks to a modular design and optional measurement modules, QSense Explorer is a versatile instrument that enables you to extend your measurement conditions and combine measurements with several other technologies.
- [QSense™ Analyzer](https://www.nanoscience.com/products/qsense-quartz-crystal-microbalance/qsense-analyzer/): QSense Analyzer produces high-quality data from four measurements in parallel. The smart design with 4 removable flow modules makes it easy to set up new experiments. QSense Analyzer will quickly become a workhorse in your lab.

## White Papers
- [Role of Desktop SEM in Rare Earth Element Exploration and Processing](https://www.nanoscience.com/applications/role-of-desktop-sem-in-rare-earth-element-exploration-and-processing/): Rare earth elements (REEs) are essential to many of today&#039;s most advanced technologies, including electric vehicles, renewable energy systems, consumer electronics, aerospace components, among many others. Although relatively abundant in the Earth&#039;s crust, economically viable REE deposits are difficult to identify and extract due to their complex mineralogy and challenging processing requirements.&nbsp;
- [SEM &#038; BIB milling for QA, QC, and Failure Analysis in Semiconductor Devices](https://www.nanoscience.com/applications/scanning-electron-microscopy-sem-and-broad-ion-beam-bib-milling-for-qa-qc-and-failure-analysis-in-semiconductor-devices/): Modern semiconductor devices feature critical dimensions well below the limits of optical inspection methods.  SEM provides nanometer-scale resolution, enabling visualization of fine details such as line edge roughness (LER), critical dimension (CD) variations, contact and via integrity and gate and interconnect profiles. This level of detail is essential for identifying subtle process deviations before they impact yield or device performance.
- [Fabrication and Characterization of Electrospun Fibers](https://www.nanoscience.com/applications/fabrication-and-characterization-of-electrospun-fibers/): Polymer fibers are produced from synthetic or natural polymers and engineered to deliver a wide range of mechanical, chemical, and functional properties. Polymer chemistry, molecular weight, and additives can be modulated to achieve specific strength, elasticity, thermal stability, biocompatibility, or chemical resistance. This versatility enables polymer fibers to be lightweight yet strong, cost-effective, and scalable; making them suitable for applications ranging from high-performance textiles and composite reinforcement to medical devices, filtration media, and energy storage systems.
- [Understanding Nickel Manganese Cobalt (NMC) Precursor Cathode Active Material (pCAM)](https://www.nanoscience.com/applications/understanding-nickel-manganese-cobalt-nmc-precursor-cathode-active-material-pcam/): As the battery industry strives for more efficient and environmentally friendly solutions in the age of electric vehicles, innovations on the level of precursor cathode active material (pCAM) have increased in popularity. As a fundamental battery material, the micro and nanoscale properties of pCAM powder highly influence the overall performance of the batteries made with it. Characterizing pCAM properties, such as size distribution and crystal orientation, can be performed using scanning electron microscopy (SEM). For improved imaging of pCAM cross sections, broad ion beam (BIB) milling can be used to remove the amorphous surface layers caused by mechanical polishing.
- [Enhancing Medical Device Performance Through Electrospinning](https://www.nanoscience.com/applications/enhancing-medical-device-performance-through-electrospinning/): Medical devices play a crucial role in modern healthcare, enabling diagnosis, treatment, and rehabilitation across a wide range of medical conditions. From simple tools such as wound dressings and catheters to complex implantable systems and regenerative scaffolds, these devices rely on materials and designs that interact safely and effectively with biological tissues. Recently, electrospinning has become a popular choice for medical device developers due to its tunability and compatibility with a wide range of polymers.
- [Electrospinning for Tissue Engineering](https://www.nanoscience.com/applications/electrospinning-for-tissue-engineering/): Advancements in the field of tissue engineering help improve medical treatment outcomes by accelerating healing, improving infection resistance, and reducing the need for human donors. By combining key principles from cell biology, biomaterials science, and mechanical engineering, tissue engineering technologies aim to replicate the structures and functions of native tissues. Various methods have been explored to fabricate materials for this application, but electrospinning offers unique advantages that have expanded the capabilities of tissue engineered treatments.
- [Using automated SEM/EDS analysis to enhance parts cleanliness and identify killer particles](https://www.nanoscience.com/applications/using-automated-sem-eds-analysis-to-enhance-parts-cleanliness-and-identify-killer-particles/): In today’s precision-driven manufacturing landscape, part cleanliness isn’t just a quality benchmark, it’s a critical factor that can make or break product performance and reliability. This is especially relevant in industries like automotive, aerospace, and medical devices, as microscopic contaminants can cause significant downtimes in production and degrade product quality. Traditional cleanliness inspection methods, including optical microscopy, often fall short in providing the resolution and compositional analysis needed to accurately identify contamination sources.
- [Optical vs. Force Tensiometry](https://www.nanoscience.com/applications/optical-vs-force-tensiometry/): Surface and interfacial tensions of liquids significantly affect their wetting behavior and interactions with other substances. These forces influence how liquids spread on solid surfaces, which are critical to coating processes like bonding, painting, and printing. In other industrial processes, like the production of food, cosmetics, pharmaceuticals, and agrochemicals, the surface and interfacial tensions can govern product stability when forming foams and emulsions. Surface tension also plays a key role in the effectiveness of cleaning agents.
- [Phenom Pharos: A Compact Desktop STEM for Screening Negative Stained Samples](https://www.nanoscience.com/applications/phenom-pharos-a-compact-desktop-stem-for-screening-negative-stained-samples/): The Phenom Pharos Desktop SEM/STEM is a compact and affordable solution designed for cryo-electron microscopy groups and core facilities looking to streamline experimental workflows. This technical note evaluates the Phenom Pharos’ performance in imaging negatively stained samples, demonstrating its effectiveness as an alternative to aging room-temperature TEMs. Additionally, the application of the Phenom Pharos for grid inspection is explored, highlighting its utility in preparing and optimizing samples for cryo-EM analysis.
- [Accounting for Surface Roughness in Contact Angle Measurements: A Practical Approach](https://www.nanoscience.com/applications/accounting-for-surface-roughness-in-contact-angle-measurements-a-practical-approach/): Contact angle measurements are a fundamental tool to understand the chemistry of surfaces and their wetting properties. Typically measured with side-on optical tensiometry, contact angle measurements are carried out by placing a liquid droplet on a solid surface, capturing images of the droplet on the surface, and using software to fit and measure the resulting angle at the edge of the droplet. For over 200 years, Young’s description of the contact angle, a balance of the surface and interfacial tensions at the solid, liquid, and gas phase boundary, has remained pertinent.
- [Automated SEM/EDS Monitoring of Steel Inclusions for Compliance with ASTM Standards](https://www.nanoscience.com/applications/automated-sem-eds-monitoring-of-steel-inclusions-for-compliance-with-astm-standards/): In modern steel manufacturing, non-metallic inclusions represent a critical quality concern due to their effects on mechanical properties and overall steel functionality. Scanning electron microscopy (SEM) and energy dispersive X-ray spectroscopy (EDS) have immense value for the in-depth analysis of these inclusions, offering higher resolution and compositional data over traditional optical methods. The integration of SEM/EDS for effective inclusion characterization is explored, specifically with the Phenom ParticleX Steel Desktop SEM. In addition, the impact of non-metallic inclusions on steel properties is detailed, while the use of ASTM standards E45, E2142, and E2238 in setting benchmarks for inclusion assessment is described. Enhanced by automated SEM/EDS technologies, steelmakers can now achieve higher precision in detecting and classifying inclusions.
- [Cross-Section Polishing for Microanalysis](https://www.nanoscience.com/applications/cross-section-polishing-for-microanalysis/): Characterizing internal structures using a surface analysis technique like scanning electron microscope (SEM) requires the preparation of a cross section of the sample. Cross-sectional sample prep involves generating a clean, precise slice through a material to expose its subsurface layers. Mechanical cutting or grinding methods are commonly used for cross section sample preparation. However, in many cases these methods damage or obscure the details that need to be observed resulting in inaccurate measurements and incorrect conclusions. Ion Milling, also known as cross section polishing, is a more advanced and refined technique that uses a beam of ionized inert gas, typically argon, to abrade the surface of a sample in an even and controlled manner. This process results in a clean, precise cross section wherein the integrity of the internal structures of a sample is preserved, and detailed analysis can therefore be conducted.
- [Surface Roughness in Contact Angle Measurements &#8211; A Theoretical Perspective](https://www.nanoscience.com/applications/surface-roughness-in-contact-angle-measurements-a-theoretical-perspective/): Contact angle measurements are a fundamental tool to understand the chemistry of surfaces and their wetting properties. Typically measured with side-on optical tensiometry, contact angle measurements are carried out by placing a liquid droplet on a solid surface, capturing images of the droplet on the surface, and using software to fit and measure the resulting angle at the edge of the droplet. For over 200 years, Young’s description of the contact angle, a balance of the surface and interfacial tensions at the solid, liquid, and gas phase boundary, has remained pertinent.
- [Detecting Residual Solvent in Polymer films with Contact Angle Measurements](https://www.nanoscience.com/applications/detecting-residual-solvent-in-polymer-films-with-contact-angle-measurements/): Thin polymer films, membranes, and coatings are vital for functionalizing surfaces, as a protection layer, filtering chemicals, or tuning a material’s surface interactions. When fabricating thin polymeric layers, organic solvents are used to dissolve the polymer to reach a low enough viscosity or a specific phase for processing. This is common with thin polymer films formed with spin coating, porous polymer membranes made with non-solvent induced phase separation (NIPS), and polymeric nanofibers and particles fabricated with spray coating techniques like electrospinning/spraying. Ideally, the solvent is then removed amid manufacturing or with post-processing conditions. However, the need and effectiveness of post-processing to remove residual solvents are not always known or verified.
- [Large-scale SEM Imaging with Automated Image Mapping](https://www.nanoscience.com/applications/large-scale-sem-imaging-with-automated-image-mapping/): Acquiring large-scale images using SEM can result in trade-offs between resolution and time-to-data, making the technique difficult to apply in applications where large field-of-view imaging is needed. This Tech Note explores the Automated Image Mapping (AIM) application for Phenom Desktop SEM, which provides a solution for conducting high-resolution analyses over large sample areas.
- [Optimizing Chemical Mechanical Planarization (CMP) Processes with QCM-D](https://www.nanoscience.com/applications/optimizing-chemical-mechanical-planarization-cmp-processes-with-qcm-d/): Chemical mechanical planarization (CMP), also called chemical-mechanical polishing, is a critical set of processes in semiconductor manufacturing. CMP utilizes chemical etching and physical grinding with abrasive materials to level or planarize semiconductor components between layers, ensuring proper current flow and thermal dissipation in the finished product. While significant advancements have been made in semiconductor technology in recent years, understanding of CMP processes is incomplete . Here we discuss how Quartz Crystal Microbalance with Dissipation Monitoring (QCM-D) can be used to simulate various CMP processes to characterize the molecular interactions taking place and optimize polishing slurries, process protocols, and more.
- [Leveraging Contact Angle Measurements to Predict Polymer Blending](https://www.nanoscience.com/applications/leveraging-contact-angle-measurements-to-predict-polymer-blending/): Plastics made from polymeric materials are an integral part of many consumer goods and products. Whether it is the packaging or the product itself, different polymers can provide material and mechanical properties to suit the product’s functional needs. With the increased integration of environmentally sustainable polymers along with concerns over the recyclability of conventional plastics, polymer blends may be sought after to achieve ideal performance properties while wholly unavoidable when recycling products that contain multiple polymers. The challenge with polymer blends is that many polymers form an incompatible final structure. In fact, two of the most common consumer-based polymers polypropylene and polyethylene, when mixed, can have poor impact resistance and interfacial adhesion.1,2 To avoid this, additional polymeric ‘compatibilizers’ may be added to improve the miscibility. Therefore, methods are needed to quickly and easily determine if polymers can form compatible mixtures or which compatibilizers will most improve the final blend.
- [Monitoring Technical Cleanliness with Automated SEM &#038; EDS](https://www.nanoscience.com/applications/monitoring-technical-cleanliness-with-automated-sem-eds/): Technical cleanliness is the exhaustive control of contamination across manufacturing and assembly of components to protect product integrity. In precision systems, undesirable particles can be detrimental to functionality, eroding and abrading surfaces through repetitive contact (Figure 1). Trapped between tight fits, they essentially act as microscopic sandpaper between components – or in some cases – stress concentration points that introduce cracks and fractures. In other cases, conductive particles short-circuit electronic pathways by bridging metal traces and power sources. Unwanted contamination can originate internally (e.g., wear and tear debris) or externally (e.g., environmental particles introduced by production tools and ambient air, including particulates of steel, brass, SiO2, and aluminosilicates). These relentless microscopic threats exist across every industry where precision matters.
- [Preparing Powders for Scanning Electron Microscopy](https://www.nanoscience.com/applications/preparing-powders-for-scanning-electron-microscopy/): Powders are one of the most common forms of materials that are analyzed using scanning electron microscopy (SEM). The distribution of particle sizes, composition, and surface morphology plays an important role in determining their behavior in different environments. Powders have found utility in every industry around the world, whether it be to formulate beauty products, enhance the bioavailability of pharmaceuticals, or as raw material in additively manufactured components. Therefore, studying the tiny particles that make up powder samples is a vital part of many scientific pursuits and industrial applications.
- [Overcoming Obstacles in Food Science with QCM-D](https://www.nanoscience.com/applications/overcoming-obstacles-in-food-science-with-qcm-d/): Food science plays a crucial role in meeting the demands of a growing population, ensuring a consistent supply of safe and nourishing food, and promoting sustainable practices to minimize waste. Each step in the journey from raw materials to packaged food products presents different challenges, which can be addressed using various tools and analytical techniques. In this application note, we explore how Quartz Crystal Microbalance with Dissipation Monitoring (QCM-D) is valuable for quantifying the molecular interactions that define the quality, appearance, and sensory characteristics of foods and food ingredients. 
- [Characterization of Proton Exchange Membrane Fuel Cell Components](https://www.nanoscience.com/applications/characterization-of-proton-exchange-membrane-fuel-cell-components/): Fuel cells are electrochemical devices that can provide clean, renewable energy for widespread applications, from powering handheld devices to entire buildings. Of the various fuel cell types, arguably the most promising are the proton exchange membrane (PEM) fuel cells, also called polymer electrolyte membrane fuel cells or PEMFCs. These devices most commonly use hydrogen gas as fuel along with oxygen from the air as an oxidizer, producing electricity with the only byproduct being water. PEMFCs also demonstrate efficiencies as high as 65%; however, their cost of approximately $75 per kW is currently a major limiting factor for widespread production and use .
- [Optimizing Lithium-Ion Battery Materials with Force Tensiometry](https://www.nanoscience.com/applications/optimizing-lithium-ion-battery-materials-with-force-tensiometry/): Batteries are a decisive element of modern mobile power consumption. While batteries have already been integrated irrevocably into smaller devices such as smartphones or portable computers, rechargeable batteries are increasingly used to propel larger energy consumers like cars and trucks as we shift our reliance away from energy resources based on fossil fuels. With goals like 50% of all new vehicle sales being electric by 2030 in the US, the demand for batteries will keep increasing.
- [Automated Gunshot Residue Analysis Using Scanning Electron Microscopy](https://www.nanoscience.com/applications/automated-gunshot-residue-analysis-using-scanning-electron-microscopy/): Meticulous collection, analysis, and interpretation of material obtained from crime scenes are imperative in ensuring accurate evidence is presented during legal proceedings. Forensic scientists investigate a diverse range of samples depending on the type of crime scene. From extracting trace DNA to deciphering blood spatter patterns and elucidating ballistics, their work plays a pivotal role in the pursuit of justice. Recognizing the profound impact physical analysis has on resolving crimes, it is necessary to employ analytical tools that are exceptionally accurate and reliable.
- [Python Programming for SEM Automation](https://www.nanoscience.com/applications/python-programming-for-sem-automation/): Scanning electron microscopes (SEMs) are staple tools for analyzing the structures and elemental makeup of surfaces with high resolution. Bringing SEM instruments in-house can provide immense value to organizations that require microstructural analysis and prioritize fast turnaround times.. Integrating these complex instruments into existing workflows or research processes can be a significant undertaking, and several challenges may arise during the process.
- [Analyzing Morphological and Mechanical Properties at the Microscale for Tissue Engineering](https://www.nanoscience.com/applications/analyzing-morphological-and-mechanical-properties-at-the-microscale-for-tissue/): Regenerative medicine is an evolving field focused on developing advanced technologies that harness the body’s natural healing abilities to restore or replace damaged tissues and organs in the body lost due to disease, trauma, defects, or aging. This field can potentially reduce the need for surgeries, long-term medications, and rehabilitation, leading to faster recovery and improved quality of life for patients.
- [Surface Free Energy for Monitoring Surface Cleanliness](https://www.nanoscience.com/applications/surface-free-energy-for-monitoring-surface-cleanliness/): Surface Free Energy (SFE) of a solid surface is analogous to the surface tension of a liquid. Just as the surface tension of a liquid is a result of the force imbalance that occurs due to the termination of cohesive forces above a liquid with quantities governed by intermolecular interactions, the SFE is essentially the same, but at an air-solid interface. SFE has a unit of millinewton per meter (mN/m) and is related to the wettability of a surface.
- [Controlling the Orientation of Electrospun Nanofibers for Tissue Engineering](https://www.nanoscience.com/applications/controlling-the-orientation-of-electrospun-nanofibers-for-tissue-engineering/): Electrospinning is a versatile and promising technique for fabricating nanofibrous scaffolds that can biomimic the extracellular matrix (ECM) of natural tissues. These nanofibrous scaffolds have several unique properties, including a high surface area-to-volume ratio, adjustable pore size, and tunable mechanical and biochemical properties. The mechanical properties of fiber scaffolds can be easily tailored by adjusting the fiber diameter, density, orientation, and polymer composition. This can allow for the creation of scaffolds with a range of mechanical properties that mimic natural tissues’ properties.
- [Overcoming the Learning Curve of CRYO-EM Sample Preparation](https://www.nanoscience.com/applications/overcoming-the-learning-curve-of-cryo-em-sample-preparation/): Advancements in cryogenic transmission electron microscopes coupled with recent breakthroughs in detectors and automation have moved single-particle cryo-EM from its revolution phase to a faster, more powerful era. Software and automation for operating transmission electron microscopes and processing data have made the technique easier and more accessible than ever. These technological developments have lowered the bar of entry to what was normally considered to be an investigative technique with a high barrier of entry and a steep learning curve. However, little has changed in the sample preparation workflow since the 1980s and remains one of the biggest obstacles to cryo-EM becoming more accessible.
- [Contact Angle Measurement for Monitoring Surface Cleanliness](https://www.nanoscience.com/applications/contact-angle-measurement-for-monitoring-surface-cleanliness/): Surface contamination is a concern for a wide variety of industries and their production processes such as polishing, surface treatments, coatings, bonding, and etching. Contamination can arise from a variety of sources, such as process oils and lubricants, aerosolized particles, residues from handling, or chemical reactions like oxidation. Downstream processes like coating applications, chemical and/or mechanical polishing, surface treatments, and mechanical assembly could be affected by these contaminants. The presence of contaminants during the downstream process could lead to a significant waste of time and materials. To prevent large-scale waste and to keep costs in line, tracking the overall level of surface cleanliness is often implemented at various checkpoints throughout the manufacturer’s process. A robust and effective testing protocol can enable a higher level of quality control. An effective testing protocol needs to be sensitive to a wide variety of surface contaminants, be quantitative, and be easy to implement.
- [Morphological and Compositional Analysis of Battery Materials](https://www.nanoscience.com/applications/morphological-and-compositional-analysis-of-battery-materials/): The crux of energy storage research concerns optimizing the properties of electrochemical devices to improve efficiency, reliability, safety, and cost – four core concepts that push ceaseless efforts into the battery industry. Since batteries are such a ubiquitous technology, critical to the everyday lives of billions, it is easy to recognize why diagnosing them and revamping them, with respect to those core concepts, are paramount objectives.
- [Bioavailability of Pharmaceutical Nanoparticle Formulations](https://www.nanoscience.com/applications/bioavailability-of-pharmaceutical-nanoparticle-formulations/): Every affliction of the body has its respective remedy, some targeted solution designed to alleviate or prevent negative health effects. Such remedies may have a long list of responsibilities to carry out once administered into the body – to soothe headaches, halt dripping noses, and calm itchy throats – but they all share one fundamental principle: have the highest therapeutic effectiveness possible. Formulation scientists are therefore tasked with leveraging properties of drugs on the micro and nanoscales to ensure that treatments act quickly and vigorously. To scrutinize characteristics on such small scales is to overcome the limitations of optical microscopy; and employing a more advanced technique – SEM (scanning electron microscopy) – is key.
- [In Situ Monitoring of the Solid Electrolyte Interphase](https://www.nanoscience.com/applications/in-situ-monitoring-of-the-solid-electrolyte-interphase/): A good understanding of different electrochemical processes that occur inside a device is critical for the optimization of various components of rechargeable batteries. Since all critical processes of batteries and other energy storage systems occur at the electrode-electrolyte interface, researchers have focused their attention on analyzing and decrypting the enigmatic events at this interface, leveraging electrochemical QCM-D (EQCM-D) for their investigations.
- [Superhydrophobicity, Oleophobicity, and Contact Angle](https://www.nanoscience.com/applications/superhydrophobicity-oleophobicity-and-contact-angle/): Superhydrophobic and oleophobic surfaces are receiving increased attention because of their potential to provide breakthroughs in applications such as anti-fouling, self-cleaning, and anti-freezing. Contact angle measurements are often used to characterize the properties of these surfaces. However, the low wettability of these surfaces presents unique challenges when trying to place a liquid droplet for measurement. Additionally, more complex measurements such as advancing (ACA), receding contact angle (RCA) and tilting angle (sometimes called roll-off angle) measurements may be necessary to characterize not just whether a material has a high contact angle, but also whether the material resists liquid adhesion. The Attension Theta Flex is a modular system that has many options for dispensers, needles, and measurement methods to quantify key performance metrics for superhydrophobic and oleophobic surfaces.
- [Controlling temperature and relative humidity for electrospinning and electrospraying sample development](https://www.nanoscience.com/applications/controlling-temperature-and-relative-humidity-for-electrospinning-and-electrospraying-sample-development/): Over the past decade, the emergence and evolution of electrospinning and electrospraying manufacturing techniques have accelerated the development of various applications including tissue engineering, drug delivery, filtration, and energy storage. Both electrospinning and electrospraying have grown in popularity because of many specific advantages over more traditional manufacturing technologies. These include the use of a wide selection of materials, highly controllable nano-scale fiber/particle diameter (typically 20 nm to 10 µm), the ability to encapsulate active ingredients, targeted fiber/particle orientation, controlled porosity, and scalability.
- [Effect of Excipients, Storage, and Formulation Conditions on Therapeutic Protein Stability](https://www.nanoscience.com/applications/effect-of-excipients-storage-and-formulation-conditions-on-therapeutic-protein-stability/): During manufacturing, storage and delivery processes, therapeutic proteins encounter several surfaces and materials, such as metals, glasses, oils, and polymers. These can range from stainless-steel production vessels to glass prefilled syringe delivery devices. The inherent surface-active nature of proteins can cause them to interact with surfaces, leading to possible denaturation and subsequent aggregation. This aggregation can produce safety related issues like unwanted immune responses, undesired cross-reactivity, or loss of efficacy.
- [Cleanliness and quality control testing by contact angle – how clean is my surface?](https://www.nanoscience.com/applications/cleanliness-and-quality-control-testing-by-contact-angle-how-clean-is-my-surface/): Contamination can have a wide variety of undesirable effects in manufacturing processes such as polishing, surface treatment, coating application, and etching. Some sources include finger oils from handling, atmospheric dust and dirt, and process lubricants. While best practices such as personal protective equipment use and appropriate transportation will help keep samples clean, it maybe necessary to apply precleaning steps to ensure a reproducible level of cleanliness. Post cleaning, surfaces may require testing to confirm whether they are ready to proceed to the next step. The ideal test measurement is quantitative, sensitive, fast, automated, and easy to interpret. Contact angle is one such measurement that can fulfill these requirements.
- [Measuring the contact angle, surface free energy and wettability of powders](https://www.nanoscience.com/applications/measuring-the-contact-angle-surface-free-energy-and-wettability-of-powders/): For powdered materials such as pharmaceuticals, dyes, proppants, and foods, wettability is an important parameter to characterize. As the powders are immersed into a liquid, fluid may wick into the interstitial spaces between powder particles through capillary forces. The wettability of the powder can be measured with a tensiometer and is related to properties such as bioavailability, color spreading, crush resistance, and mouthfeel. The sessile drop technique utilizes an optical tensiometer and is one option for measuring powder wettability. In this measurement, a drop of liquid is placed onto a surface and the contact angle is measured. Larger contact angle values (&gt; 90°) indicate poor wettability and, smaller contact angle values (&lt; 90°) indicate good wettability.
- [Optical Tensiometry as a Tool to Measure Coating Properties and Substrate Adhesion](https://www.nanoscience.com/applications/optical-tensiometry-as-a-tool-to-measure-coating-properties-and-substrate-adhesion/): Coatings are used to modify the properties of the substrate that they cover and are ubiquitous in our everyday lives. They can have functional, protective, and/or aesthetic purposes. One everyday example of a coating is the touchscreen on a smartphone. The coatings on these screens repel oils, which allows a finger to glide easily on the surface. The coatings also provide some protection to the underlying glass and makes the phone look glossy and attractive.
- [Characterization of Surfaces and Surface Reactions in Energy Storage using EQCM-D](https://www.nanoscience.com/applications/characterization-of-surfaces-and-surface-reactions-in-energy-storage-using-eqcm-d/): There has been a global shift from fossil fuels to renewable energy to protect civilization from the worst effects of climate change. Special focus has been given to solar and wind energy. However, utilizing electricity from solar and wind in a grid becomes challenging due to their intermittent nature. The supply of sunlight or wind is not constant; thus, it cannot meet the constant demand for electricity. Energy storage, via batteries for example, is required for continuous energy supply as well as for ensuring stability of the grid by responding quickly when unexpected increases in demand occur.
- [Dilatational Rheology of Foams, Emulsions, and Suspensions](https://www.nanoscience.com/applications/dilatational-rheology-of-foams-emulsions-and-suspensions/): Emulsions and foams play a key role in important products such as foods1, pharmaceuticals2, and oil recovery formulations3. The stability of these products plays a key role in their performance and shelf life. Amphiphilic molecules such as surfactants, proteins, and polymers are key components in these emulsions and foams. These molecules will preferentially adsorb to the air-liquid or liquid-liquid interface in a specific orientation to minimize their free energy. Over the course of their storage and consumption, these materials will flow over each other and change the size and shape of their interfaces constantly. The study of how these molecules respond to external deformations and stimuli is called interfacial rheology.
- [Phenom Desktop SEM: ParticleX as an Enabling Technology in Additive Manufacturing](https://www.nanoscience.com/applications/phenom-desktop-sem-particlex-as-an-enabling-technology-in-additive-manufacturing/): In the past two decades additive manufacturing (AM) has rapidly evolved from a cutting-edge technology into a routine manufacturing method. The ability to quickly print complex shapes in a cost-effective and energy efficient manner has helped revolutionize the go to manufacturing method in a huge number of industries. Even with this rapid adoption various engineering challenges still exist. One of the most well-known challenges associated with metal additive manufacturing is that pertaining to the varying levels of porosity associated with the 3D printed metal part.
- [How Interfacial Rheology Can Replace Inefficient Emulsion Characterization in Droplet-Based Microfluidics](https://www.nanoscience.com/applications/how-interfacial-rheology-can-replace-inefficient-emulsion-characterization-in-droplet-based-microfluidics/): There are a lack of tools to efficiently predict emulsion stability. Stabilizing emulsions is a significant problem in foods , personal care products , pharmaceuticals , and droplet-based microfluidics. Some major applications of droplet-based microfluidics include single-cell gene sequencing , anti-body screening and drug discovery , and synthesis of functional nanomaterials . In these applications, single droplets encapsulate materials such as single cells, and the droplets must remain stable and not coalesce or else the analysis or reactions can be ruined. This is complicated by the fact that droplets often must incubate for long times, cycle through several temperatures such as in PCR, and often contact each other. The choice of filler fluid, droplet phase, and additives in either heavily influences drop stability, but making the best choice of components is not trivial. Interfacial tension measurements are commonly made, but these are poor predictors of drop stability. Instead, often formulations are simply run through the microfluidic system to see if they are successful. This can not only take a long time, but the materials can be expensive and limited.
- [Automation and Jet Vitrification: Keys to Revolutionizing Single Particle Analysis Sample Preparation](https://www.nanoscience.com/applications/automation-and-jet-vitrification-keys-to-revolutionizing-single-particle-analysis-sample-preparation/): Plunge freezing has been the gold standard for cryoEM single particle sample prep several decades now . For better and for worse, it did the job. It’s been the method that cryoEM users have relied on to create the samples which have been used in thousands of groundbreaking publications around the world. Although they have their limitations, plunge freezing and blotting have left an unforgettable mark on this research. However, we’re excited to move the state of the art forward as it relates to grid preparation. With more scientists eager to get 3D reconstructions of their proteins, automated grid preparation is the most efficient way to improve the effectiveness of the cryoEM workflow. Using the VitroJet time to structure will be decreased bringing more knowledge and breakthroughs while reducing the headaches experienced in sample preparation. We believe automation through jet vitrification will be the future of sample preparation in your lab and solving more structures in your lab.
- [Effectiveness of DIY masks: How do they work?](https://www.nanoscience.com/applications/effectiveness-of-diy-masks-how-do-they-work/): The rapid worldwide spread of the novel coronavirus, also known as COVID-19, has upended all conventional thinking regarding the scope of the damage it is causing and ways to control the spread. Although washing hands frequently and maintaining social distancing are the guidelines to help control the spread, new recommendations regarding the role of public usage of nonmedical fabric facemasks is being recommended by CDC in areas of significant community spread. Homemade face masks, while providing some protection, also do not put extra pressure on the already strained supply chains for medical staff.
- [Effectiveness of Masks: Fast Answers with Automated SEM Analysis](https://www.nanoscience.com/applications/effectiveness-of-masks-fast-answers-with-automated-sem-analysis/): The worldwide spread of COVID-19 has everyone questioning how to protect themselves and help those on the front line of the coronavirus. The CDC recommends facemasks be used for those that have COVID-19 or are showing symptoms and now for anyone in areas with significant community-based transmission. Facemasks are also crucial to healthcare workers and those taking care of someone infected with the virus. Some innovative people are making DIY masks to donate to hospitals in critical need. The next natural question that arises is how well do these homemade masks work? How would their effectiveness be measured? In this two-part series, we will look at the differences between the recommended masks and other materials. In part two, we will examine the different materials that are being recommended for DIY facemasks.
- [Analyzing cleaning of hard surfaces using QCM-D](https://www.nanoscience.com/applications/analyzing-the-cleaning-of-hard-surfaces-using-qcm-d/): Use of surgical masks and other PPE, frequent washing of hands with soap and water, and regular cleaning of hard surfaces has been recommended by the CDC to combat the spread of novel coronavirus.
- [Why Your Surgical Mask Orientation Matters: How We Use Wettability to our Advantage](https://www.nanoscience.com/applications/why-your-surgical-mask-orientation-matters-how-we-use-wettability-to-our-advantage/): Amid the COVID-19 pandemic, surgical masks and N95 respirators (Fig. 1) have gained significant media attention, both for their use as personal protective equipment (PPE) and their limited supply. While the Centers for Disease Control and Prevention (CDC) does not recommend that the public wear N95 respirators, it is recommended that you wear a surgical mask if you are sick or are caring for someone who is sick. That means many people may be putting on a surgical mask for the first time, and it is important that the correct side of the mask is facing out.
- [Simultaneous Characterization of Topography and Contact Angle](https://www.nanoscience.com/applications/simultaneous-characterization-of-topography-and-contact-angle/): To ensure the safety and quality of medical implants, parameters such as the roughness, cleanliness, and wettability of the surface must be characterized. Because these properties are all coupled to some degree (for example, roughness may enhance the hydrophobic or hydrophilic effects of a surface), it may be insufficient to simply take a single value, such as the contact angle, to fully understand the state of the surface. By combining a topographical measurement with the contact angle, the corrected contact angle and surface energy can be obtained. These values can then be used to determine not only whether the roughness treatment has yielded the desired result, but also whether the surface is free of contaminants.
- [Virus Detection with Quartz Crystal Microbalance (QCM-D)](https://www.nanoscience.com/applications/virus-detection-with-quartz-crystal-microbalance-qcm-d/): Development of an accurate test to determine whether a person has been infected is a complementary step for ensuring a healthy populace. Virus detection methods include antibody tests, DNA or RNA tests, and antigen tests. Successful engineering of these tests involves understanding the components of the virus that can most specifically and sensitively identify it. For some viruses, this can involve looking for antibodies or viral antigens that a person has produced. In other cases, this may require extraction of the viral DNA or RNA to match a complementary strand . Either strategy requires a high-content, highly sensitive technique that can accurately and reproducibly determine binding of these molecules.
- [Enhancing EOR with High-Pressure Contact Angle Measurements](https://www.nanoscience.com/applications/enhancing-eor-with-high-pressure-contact-angle-measurements/): As oil demand continues to rise, many oil reservoirs are no longer capable of producing oil by traditional primary and secondary extraction methods. To extract these oils, enhanced oil recovery (EOR) techniques that aim to improve oil mobility through lowering oil viscosity, lowering interfacial tension, and reducing wettability of oil on reservoir surfaces, are needed. Understanding how EOR approaches alter interfacial tension and wettability is important, and these properties are heavily dependent on temperature and pressure, it is crucial to have the ability to measure these properties at temperatures and pressures relevant to reservoir conditions.
- [Quantifying Enhanced Wettability and Time-dependency of Plasma-treated Polypropylene](https://www.nanoscience.com/applications/enhanced-wettability-plasma-treated-polypropylene/): When applying coatings, inks, adhesives, and other materials to a surface, controlling the surface properties becomes critical. In particular, the wettability – the ability of the process liquid to spread and adhere to the solid surface – needs to be controlled. As more products rely on plastics, from medical devices to automobile bumpers, this concept has grown more important since plastics generally exhibit poor wettability for many liquids. This is due to the low surface free energy of many plastics. For example, polypropylene (PP), a widely used polymer due to its low cost, machinability, good chemical resistance and mechanical properties, is naturally hydrophobic, causing many water-based liquids to poorly wet the material.
- [Accurately Monitoring Interfacial Tension of Transformer Oil Quality](https://www.nanoscience.com/applications/transformer-oil-quality/): Transformers account for nearly 60% of the cost of high voltage substations , and the time to repair some transformers is over one year . Given the long downtime for repairs, t is imperative to accurately monitor the health of the transformer. Over time, transformer insulator oil degrades due to mechanical, electrical, and chemical stresses, and its quality is an excellent indicator of a transformer’s condition . For years, measuring the interfacial tension (IFT) between the transformer oil and water according to the ASTM D971 standard has been effectively used to monitor oil and transformer health. This is made easier with the Attension Sigma 702ET Transformer Oil Analyzer, the only tensiometer on the market dedicated to the quality control of transformer oils.
- [Use the Right Tools to Create the Best EBSD Images](https://www.nanoscience.com/applications/ebsd-sample-preparation/): In Electron Back Scatter Diffraction (EBSD) studies, surface quality is a key issue. Diffraction patterns are formed within a few tens of nanometers of the sample surface. A crystalline, damage-free and oxide-free surface is needed in order to get good quality EBSD patterns to visualize small-scale variability in grain- and/or crystallographic orientation. Argon broad beam ion milling treatment using Technoorg’s SEMPrep2 system provides proper sample surface for EBSD investigation. In some cases, only 10 minutes of ion milling treatment provides samples that yield excellent EBSD results.
- [High Performance Transmission Electron Microscopy with Focused Ion Beam Milling](https://www.nanoscience.com/applications/tem-ion-beam-milling/): The use of focused ion beam (FIB) systems has become the method of choice for site-specific transmission electron microcscopy (TEM) sample preparation. Although focused ion beam offers advantages over conventional mechanical and chemical TEM sample preparation, it also has the drawback of high-energy operation. The high-energy Gallium (Ga+) ion beams used in focused ion beam systems form defected, amorphous and/or implanted layer in the specimen. FIB in general produces TEM samples which are less suitable for high performance analytical (S)TEM (HRTEM, HRSTEM, high spatial resolution EELS and EDX) investigations. However, for high-resolution microscopy and high-sensitivity analysis, low-energy Argon (Ar+) ion milling is ideal for the final stage of specimen preparation in order to decrease the defected layer.
- [Fractography](https://www.nanoscience.com/applications/fractography/): Fractography is a method in failure analysis for studying the fracture surface of materials. Studying the characteristics of the fractured surface can help to determine the cause of failure in an engineered product. Different modes of failure produce characteristic features on the surface, allowing a forensic analysis to determine the root cause of the failure.
- [Evaluation of Filtration Fibers &#038; Membranes](https://www.nanoscience.com/applications/evaluation-fibers-membranes/): Fiber-based filtration systems clean everything from the air we breathe to the oil that runs our engines. Many filters, like high-efficiency particulate air (HEPA) and ultra-low particulate air (ULPA) filters, are made from glass or polymer fibers. Some are a woven mesh of metal fibers, while others are manufactured from nonwoven media.&nbsp;Some filters even use a thin layer of nanofibers to increase performance and efficiency.&nbsp;Filter shapes, sizes, and compositions vary widely depending upon the application. Efficient and effective filters are important in homes, businesses, and manufacturing environments.
- [Fiber and Filter Quality Measurements](https://www.nanoscience.com/applications/quality-measurements/): Speeding up quality control and assurance analysis in manufacturing is a goal across many industries, including for fiber and filtration.  Tabletop scanning electron microscopes help do this.  The Phenom tabletop scanning electron microscope utilizes a unique electron source, cerium hexaboride, that yield images of high quality and detail. These images, combined with software for measuring the surface porosity and fiber density results in quantitative measurements of fiber diameters, distribution and porosity in less time than counting.
- [Grain Size Measurement of Ceramics](https://www.nanoscience.com/applications/grain-size-measurement/): Ceramics often have grain sizes and microstructure that impact material performance.&nbsp;Scanning electron microscope (SEM) images are used to quantify the grain sizes and distribution. Grain boundaries and microstructure can be optimized with ceramic processing parameters for specific product requirements.
- [Electron Microscopy of Minerals](https://www.nanoscience.com/applications/electron-microscopy-minerals/): Scanning electron microscopy is now a routine technology employed in the study of rocks and minerals. In addition to providing high-resolution images, electron microscopes generate a variety of additional signals that are often employed to further our understanding of geological samples. Chief among these are back-scatter electron detection, secondary electron detection, and energy-dispersive X-ray spectroscopy.
- [Pharmaceutical Particle Characterization](https://www.nanoscience.com/applications/pharmaceutical-particle/): Understanding the physical characteristics of particles in dry powder materials is an essential aspect of drug product development. The particle size distribution of either active pharmaceutical ingredients (APIs) of excipients often has a significant impact on product performance and manufacturability. Increasingly, scanning electron microscopy is being employed in order to investigate particle size, morphology and chemical composition.
- [Pharmaceutical Deformulation](https://www.nanoscience.com/applications/pharmaceutical-deformulation/): Imaging plays an integral role in the deformulation of any product. Separation and quantification of individual ingredients often require a suite of analytical instrumentation. The Phenom ProX desktop SEM with EDS is the ideal tool for accurately measuring pharmaceutical particle morphology, sizes and distribution and determining the elemental composition of active pharmaceutical ingredients (API) and excipients.

## Webinars
- [Measuring Wettability and Interfacial Tension for EOR Optimization](https://www.nanoscience.com/webinars/measuring-wettability-and-interfacial-tension-for-eor-optimization/): Wettability and interfacial tension (IFT) play a decisive role in the success of enhanced oil recovery (EOR) processes. In this webinar, we explore how contact angle and IFT measurements are used to characterize fluid–rock interactions and support EOR decision-making. You’ll learn the fundamentals of the main measurement techniques, best practices for generating reliable data, and how to translate laboratory results into meaningful insights for EOR applications.
- [Accelerating Surface Particle Contamination Control by Combining Fastmicro and Phenom Technologies](https://www.nanoscience.com/webinars/accelerating-surface-particle-contamination-control-by-combining-fastmicro-and-phenom-technologies/): Surface particle contamination remains a critical challenge across advanced manufacturing industries, where particles can negatively impact yield, product quality, and process reliability. Effective contamination control requires both rapid surface particle quantification and deeper particle characterization capabilities to support root-cause analysis and process improvement.
- [Faster, Smarter Inclusion Analysis for Modern Metallurgical Labs](https://www.nanoscience.com/webinars/faster-smarter-inclusion-analysis-for-modern-metallurgical-labs/): From bearings that are used in the satellites to the specialty alloy metals used in orthopedic implants and other medical devices, the pressure for cleaner and higher quality steel, aluminum and other specialty metals is rising. Traditional optical inspections or bulk chemical analysis may be quick but only provides a small portion of the information needed to reliably improve quality while increasing the rate of production.
- [Formulation to Performance: Carbon Nanoparticle Based Polymer Nanocomposites via Micro-compounding](https://www.nanoscience.com/webinars/formulation-to-performance-carbon-nanoparticle-based-polymer-nanocomposites-via-micro-compounding/): Processing carbon-based polymer nanocomposites via melt-processing presents unique challenges due to nanoparticle agglomeration, poor dispersion, and the strong sensitivity of these systems to shear and thermal history, all of which directly impact final material performance. This webinar focuses on the melt compounding of carbon-based nanofillers such as graphene and carbon nanotubes, with particular attention to achieving homogeneous dispersion while preserving polymer integrity and maximizing filler efficiency.
- [Interfacial Stability in Monoclonal Antibody Formulations: The Role of Oleic Acid from PS80 Degradation](https://www.nanoscience.com/webinars/interfacial-stability-in-monoclonal-antibody-formulations-the-role-of-oleic-acid-from-ps80-degradation/): The adsorption of monoclonal antibodies (mAbs) at the air–water interface is a major pathway for aggregation and particle formation in therapeutic protein formulations. Polysorbate 80 (PS80) is widely used to mitigate this risk by preferentially occupying the interface; however, in highconcentration formulations PS80 can undergo enzymatic degradation, generating surface-active fatty acids such as oleic acid (OA). This study focuses on the co-adsorption of PS80 and OA at the air-water interface and its potential impact on the composition and structure of the protective excipient layer.
- [SEM Imaging: Featuring Guest Speakers from the World of Volume EM &amp; Materials Science](https://www.nanoscience.com/webinars/sem-imaging-featuring-guest-speakers-from-the-world-of-volume-em-materials-science/): The Centre for Ultrastructural Imaging (“CUI”) is the central electron microscopy unit at King’s College London, one of the most advanced EM hubs in Europe.
- [High-Resolution Nanomaterials Imaging with the Phenom Desktop SEM](https://www.nanoscience.com/webinars/high-resolution-nanomaterials-imaging-with-the-phenom-desktop-sem/): The term “nanomaterials” covers a broad range of inorganic material types, with the common feature between them being their extremely small physical size. This size range typically spans from approximately 1 to 100 nm. Acquiring scanning electron microscope (SEM), scanning transmission electron microscope (STEM) or transmission electron microscope (TEM) images of materials at this scale presents unique challenges related to resolution, signal generation, and beam–sample interactions. However, with proper sample preparation, optimized electron beam parameters, and thoughtful selection of imaging detectors, it is possible to reliably capture high-quality images of nanoscale features.
- [A New Generation of Phenom SEM: Introducing the Latest Models &#038; Software Updates](https://www.nanoscience.com/webinars/a-new-generation-of-phenom-sem-introducing-the-latest-models-software-updates/): The Phenom platform continues to evolve, delivering new levels of performance, usability, and versatility in desktop scanning electron microscopy. In this webinar, we will introduce the newest generation of Phenom SEM instruments along with the latest software updates designed to enhance imaging, analysis, and workflow efficiency. Attendees will gain an overview of key hardware advancements, new system capabilities, and software improvements that expand application flexibility and improve the overall user experience.
- [Electrospinning and Electrospraying of Plant-Based Materials for Scalable, Animal Component-Free Cell Culture Systems](https://www.nanoscience.com/webinars/electrospinning-and-electrospraying-of-plant-based-materials-for-scalable-animal-component-free-cell-culture-systems/): Advancing sustainable, animal component-free (ACF) materials for cell culture is critical for tissue engineering, regenerative medicine, and cellular agriculture, yet conventional scaffolds and microcarriers rely heavily on synthetic or animal-derived polymers that limit reproducibility, scalability, and regulatory alignment. This discussion investigates electrospinning and electrospraying as versatile fabrication strategies for producing fibrous scaffolds and hydrogel microcarriers from renewable, plant-based biopolymers, including zein, alginate, and plant protein isolates.
- [What to Expect in the Compressed Sensing Landscape for Electron Microscopy in 2026](https://www.nanoscience.com/webinars/what-to-expect-in-the-compressed-sensing-landscape-for-electron-microscopy-in-2026/): Professor Nigel Browning looks at the key advancements from 2025 and what to expect in 2026.
- [Practical SEM and Ion Mill Applications for Semiconductor R&amp;D to Production](https://www.nanoscience.com/webinars/practical-sem-and-ion-mill-applications-for-semiconductor-rd-to-production/): Scanning Electron Microscopes (SEMs) and Cross-sectioning/Polishing tools play a vital role in semiconductor development, from initial materials research to quality assurance in production. Our upcoming webinar will explore how SEMPREP SMART broad ion beam (BIB) milling systems and the Phenom benchtop SEMs can streamline sample preparation and imaging throughout the semiconductor lifecycle.
- [An Introduction to Micro Compounding](https://www.nanoscience.com/webinars/an-introduction-to-micro-compounding/): Polymer formulation can be a challenging and time-consuming process. Utilizing the well-known pilot or production scale twin screw compounder can often result in sluggish development times, cause downtime in production and yield only a few samples per week. This type of process can be even more problematic for polymer research where material is expensive or difficult to synthesize as these systems call for large amounts of material.
- [Unlocking the Power of Desktop SEM for Pharmaceutical Development and Quality Control](https://www.nanoscience.com/webinars/unlocking-the-power-of-desktop-sem-for-pharmaceutical-development-and-quality-control/): As the pharmaceutical industry grows and new products are being researched and manufactured, having access to advanced characterization tools becomes even more critical for improving development and maintaining quality.&nbsp; Desktop Scanning electron microscopy (SEM) combined with energy dispersive spectroscopy (EDS) is a powerful tool that provides valuable data quickly and easily without years of microscopy expertise required.&nbsp;
- [Automating Battery Materials Analysis using Avizo Trueput with Phenom Desktop SEMs](https://www.nanoscience.com/webinars/automating-battery-materials-analysis-using-avizo-trueput-with-phenom-desktop-sems/): Battery manufacturers face increasing demands for higher throughput, reproducible quality control, and reduced time-to-market. Traditional manual analysis of electrode materials under the scanning electron microscope (SEM) is often labor-intensive, inconsistent, and difficult to scale. Thermo Scientific’s Avizo Trueput software, when combined with Phenom Desktop SEMs, provides an automated solution for high-throughput, standardized inspections. Avizo Trueput coupled with Phenom desktop SEMS enables operators of any skill level to acquire SEM images, apply automated feature detection, and generate consistent pass/fail metrics for critical parameters such as particle size (primary and secondary), morphology, cracks, coating uniformity and more.
- [Unraveling the Fabric: Exploring Fibers and Textiles with Desktop SEM](https://www.nanoscience.com/webinars/unraveling-the-fabric-exploring-fibers-and-textiles-with-desktop-sem/): From the smoothness of a single fiber to the weave of an entire fabric, microscopic details can reveal critical insights into quality, performance, and innovation. In this webinar, we’ll show how desktop scanning electron microscopy (SEM) makes high-resolution imaging accessible to all, guiding you through best practices and advanced techniques to maximize the value of SEM in your workflow.
- [Rewriting the Interfacial Playbook with a Chemical-First Approach for Mechanistic Insights](https://www.nanoscience.com/webinars/rewriting-the-interfacial-playbook-with-a-chemical-first-approach-for-mechanistic-insights/): Understanding chemical behavior at the boundary of two phases requires a paradigm shift from how we view pure phases. The unique properties of hydrophobic-water interfaces underpin their reactivity; however, explaining the mechanisms of ‘why’ often remains elusive, confounding physical chemists like myself. Simultaneously, numerous studies have demonstrated these interfaces can promote incredible chemistry. Hence, one can only imagine the prospects when frameworks are constructed to model and explain behavior.
- [From Bench to Brain: Translating Nanofiber Drug Delivery for Glioblastoma Therapy](https://www.nanoscience.com/webinars/from-bench-to-brain-translating-nanofiber-drug-delivery-for-glioblastoma-therapy/): Glioblastoma (GBM) remains a highly aggressive brain cancer with poor prognosis, in part due to the limitations of systemic therapies crossing the blood–brain barrier and the recurrence of tumors post-resection. Interstitial drug delivery offers a promising alternative, yet current approaches often lack optimal control over therapeutic release kinetics. To address this, we developed electrospun nanofibrous scaffolds composed of acetalated dextran (Ace-DEX), a biodegradable polymer with tunable degradation and pH sensitivity, capable of modulating drug release rates. By engineering scaffolds with fast, medium, and slow degradation profiles, we achieved daily paclitaxel release rates of 14.1%, 2.9%, and 1.2%, respectively.
- [Real-time, low dose 4D-STEM Imaging](https://www.nanoscience.com/webinars/real-time-low-dose-4d-stem-imaging/): In this webinar, we will introduce the NEW low dose, live imaging for 4D-STEM from SenseAI.
- [Predicting Solution Behavior: Insights into the Developability of Biologics](https://www.nanoscience.com/webinars/predicting-solution-behavior-insights-into-the-developability-of-biologics/): Monoclonal antibodies (mAbs) are widely used in the pharmaceutical and biotechnology industries due to their high target affinity and specificity. Successful therapeutic mAb candidates must exhibit optimal manufacturability, stability, and delivery characteristics, collectively known as developability metrics. However, protein self-association and poor solution behavior continue to be major developability challenges, leading to high viscosity, opalescence, and instability, particularly in high-concentration antibody formulations. Early-stage identification of mAbs with favorable solution behavior is critical to mitigating these risks before clinical development. While several methods exist to study self-association, many rely on complex measurements that are not always feasible under relevant experimental conditions. Therefore, there is a need for relevant, robust, and predictive methods to assess mAb self-association. This study proposes the novel application of quartz crystal microbalance with dissipation monitoring (QCMD) as a self-association metric to address this gap, by analyzing the unexplored loosely bound layer (LBL) and its correlation with protein self-association and solution behavior.
- [Using QSense QCM-D to Assess &amp; Optimize Cleaning Efficiency](https://www.nanoscience.com/webinars/using-qsense-qcm-d-to-assess-optimize-cleaning-efficiency/): Analyze cleaning process dynamics, surface etching, and surface residual!
- [Polymer Micro-Processing Insights: Sustainable Formulation Starts Small](https://www.nanoscience.com/webinars/sustainable-formulation-starts-small-micro-polymer-processing-insights/): In the pursuit of a more sustainable future, formulation development must evolve to integrate innovative materials and techniques at the micro scale. Sustainable Formulation Starts Small: Micro-Polymer Processing Insights will explore how micro-polymer processing tools are reshaping the design and development of next-generation sustainable materials.
- [Applications for Desktop SEM in Geology](https://www.nanoscience.com/webinars/applications-for-desktop-sem-in-geology/): Scanning Electron Microscopy (SEM) has become a vital tool in geology, offering high-resolution imaging and elemental analysis for understanding the composition, texture, and geologic history of rocks, minerals, and fossils. While traditional SEMs have been limited to specialized labs due to their size and complexity, desktop SEMs (like the Phenom series) are making this powerful technology accessible to more users.
- [Superfast Imaging for Electron Microscopy: Up to 100x Faster, 100x Less Data and 100x Less Dose](https://www.nanoscience.com/webinars/superfast-imaging-for-electron-microscopy-up-to-100x-faster-100x-less-data-and-100x-less-dose/): In this webinar, we will introduce ‘Compressed Sensing’ software from SenseAI, which samples a fraction of the data without loss of any inherent information. This generates images faster with significantly reduced beam damage and up to 100x less data. Most importantly, there is no loss of integrity of the images.
- [Advancements in Electrospun Scaffolds: Transitioning from 1D/2D Sheets to 3D Structures](https://www.nanoscience.com/webinars/advancements-in-electrospun-scaffolds-transitioning-from-1d-2d-sheets-to-3d-structures/): Electrospinning has emerged as a leading platform for generating nanofibrous materials whose fiber dimensions and organizational motifs closely recapitulate the architecture of native extracellular matrices. Conventional electrospun mats, whether highly aligned or randomly oriented, offer excellent surface mimicry but remain limited by their two-dimensional, densely packed geometry, which impedes cellular infiltration and integration in three-dimensional tissue constructs. We explored innovative strategies to transform 1D/2D electrospun sheets into fully three-dimensional scaffolds, leveraging gas-foaming, molding, freeze-drying, and targeted postprocessing techniques. We investigated how these approaches modulate scaffold porosity, mechanical compliance, and microarchitecture, and we correlated these structural features with biological performance in both in vitro and in vivo models.
- [SEMPREP SMART: The Future of Ion Milling is Here](https://www.nanoscience.com/webinars/semprep-smart-the-future-of-ion-milling-is-here/): Ion milling is a powerful technique used in SEM sample preparation to create pristine, polished surfaces without the use of chemicals or mechanical force. However, achieving high-quality results can be challenging due to issues such as sample damage, beam-induced artifacts, thermal effects, contamination, complex geometries, alignment difficulties, and long processing times. These challenges can make it difficult to precisely target areas of interest or result in poor surface quality.
- [Dilatational Interfacial Rheology with the Pulsating Drop Module | Tensiometry Masterclass Session #6](https://www.nanoscience.com/webinars/dilatational-interfacial-rheology-with-the-pulsating-drop-module-tensiometry-masterclass-session-6/): Interfacial dilatational rheology is a useful tool to investigate the properties of liquid interfaces containing surface active compounds like surfactants, lipids, or polymers.
- [Using Automated SEM/EDS Analysis to Enhance Parts Cleanliness](https://www.nanoscience.com/webinars/using-automated-sem-eds-analysis-to-enhance-parts-cleanliness/): Maintaining technical cleanliness is critical in industries where contamination can compromise product performance, safety, and compliance. From automotive and aerospace to medical devices and microelectronics, stringent cleanliness standards help mitigate the risks associated with particulate contamination.
- [Tissue Section Analysis with Benchtop STEM](https://www.nanoscience.com/webinars/tissue-section-analysis-with-benchtop-stem/): Furthering our collective understanding of biological processes is a complex, demanding endeavor. This is partly a result of the convoluted relation between macroscopic and microscopic components. One of the best tools scientists have to unravel these mysteries is one of the base human senses, sight. Viewing what goes on underneath the surface reveals a whole new world that is otherwise invisible to us. This provides an invaluable method for analyzing tissue samples, especially for disease and drug development. Electron microscopy is one of many forms of microscopic techniques used to look at tissue but it is perhaps the most powerful. Traditionally, electron microscopes were difficult to access but as technology has advanced, so has the accessibility of this technique. Desktop SEMs have become ubiquitous across many industries as a result of ease of use, small footprint, and low cost. The Phenom series of desktop SEMs, the Phenom Pharos, is a field emission gun system with a dedicated STEM holder, able to achieve the resolutions necessary to view the ultrastructures of tissue. Join us on March 20th as we dive into the benefits of electron microscopy for tissue analysis and explore how the Phenom Pharos w/STEM fits into your workflow.
- [Get Hooked: Interfacial Tenson &#038; Captive Bubble Measurements with a Hooked Needle | Tensiometry Masterclass Session #5](https://www.nanoscience.com/webinars/get-hooked-interfacial-tenson-captive-bubble-measurements-with-a-hooked-needle-tensiometry-masterclass-session-5/): Surface and interfacial tensions are fundamental properties of liquid interfaces that determine functional outcomes in virtually any field that requires wetting, mixing, formulating, recovery, or distributing of liquids. It can also indicate the age and quality of liquid formulations, making it relevant for both liquid development and quality control. This specific measurement, using the pendant drop method, has many experimental advantages over classical force tensiometry techniques, such as using small liquid volumes and the ability to couple with dynamic conditions (interfacial rheology, high pressure, and high temperature). In a standard pendant drop measurement, a droplet is suspended from a needle tip while images of its silhouette are taken with an optical tensiometer and fitted with a drop shape analysis software. However, physical properties of the liquid, such as high volatility, extreme viscosity, and low surface tension, can make it challenging to practically implement. Similarly, measuring contact angles on hydrogels and hydrated materials can be virtually inaccessible with standard sessile drop methods.
- [Advanced Feature Analysis with PyPhenom](https://www.nanoscience.com/webinars/advanced-feature-analysis-with-pyphenom/): This webinar dives into the transformative capabilities of feature analysis in Scanning Electron Microscopy (SEM) using Python-powered tools. Discover how PyPhenom automates data extraction, enabling high-resolution measurements that drive innovation in fields like semiconductors, materials science, biomedical research, aerospace, and additive manufacturing.
- [Molecular Scale Adsorption Behavior of Per- and Poly-Fluoroalkyl Substances (PFAS) on Model Surfaces](https://www.nanoscience.com/webinars/molecular-scale-adsorption-behavior-of-per-and-poly-fluoroalkyl-substances-pfas-on-model-surfaces/): Per- and poly-fluoroalkyl substances (PFAS) are emerging contaminants of concern owing to their longevity, toxicity, mobility, and bioaccumulation. Alternative products, and chemistries, have failed to replace PFAS due to its unparalleled surfactant properties. Thus, research efforts must shift the focus onto remediation methods and mitigation strategies for PFAS removal.
- [MAPS 3: Automated Image and EDS Stitching for Phenom SEMs](https://www.nanoscience.com/webinars/maps-3-automated-image-and-eds-stitching-for-phenom-sems/): Take your Scanning Electron Microscopy (SEM) workflows to the next level with MAPS 3, a sophisticated solution designed to automate image and elemental mapping for complex samples.
- [Dynamic Contact Angle Measurements with a Tilting Stage | Tensiometry Masterclass Session #4](https://www.nanoscience.com/webinars/dynamic-contact-angle-measurements-with-a-tilting-stage-tensiometry-masterclass-session-4/): In our fourth edition of the Tensiometry Masterclass Series, we will focus on manual tilting contact angle measurements featuring the Theta Lite optical tensiometer. Dynamic contact angle and roll-off angle determined from droplet tilting are a useful way to characterize the performance of different surfaces or coatings, such as anti-fog, self-cleaning, superhydrophobic, or antimicrobial. In this masterclass, we will go through a dynamic contact angle measurement with the manual tilting stage and measure advancing and receding contact angle as well as roll-off angle. We will focus on how to properly set up and operate the tilt stage as well as capture the tilted contact angle in OneAttension.
- [Surface Matters: QSense Omni Insights on Biopharma Protein Compatibility](https://www.nanoscience.com/webinars/investigating-biopharmaceutical-protein-surface-interactions-using-qsense-omni/): A biopharmaceutical drug encounters several surfaces during its lifecycle, from production to delivery. The stability and efficacy of these drugs can be significantly influenced by their interactions with various materials.
- [It&#8217;s a Small World: Contact Angles at the Picoliter Scale | Tensiometry Masterclass Session #3](https://www.nanoscience.com/webinars/its-a-small-world-contact-angles-at-the-picoliter-scale-tensiometry-masterclass-session-3/): This session will focus on the Attension Picoliter Dispenser, which enables sessile drop contact angle measurements on samples with small surface areas, thin wires, single fibers, and more. Based on piezo-driven inkjet printing technology, the Picoliter Dispenser can dispense droplets as small as 20 picoliters, resulting in drop diameters less than 100 µm, depending on the contact angle formed. We will explore how to set up the measurement, considerations for using this unique accessory, and demonstrate experiments on various materials.
- [Measuring Roughness Corrected Contact Angle: Combined Contact Angle and Surface Roughness Measurements with 3D Topography | Tensiometry Masterclass Session #2](https://www.nanoscience.com/webinars/measuring-roughness-corrected-contact-angle-combined-contact-angle-and-surface-roughness-measurements-with-3d-topography-tensiometry-masterclass-session-2/): In the second edition of our Tensiometry Masterclass Series, we will characterize real surface wettability with roughness corrected contact angle measurements on the Theta Flow/Flex Optical Tensiometer. For real surfaces, surface roughness enhances surface wetting behavior and can significantly affect the measured contact angle. The contact angle of a surface, independent of the effect of surface roughness can be determined through roughness correction. In this masterclass, we will go through a roughness corrected contact angle measurement using the 3D topography module, measuring the material surface roughness right at the location of the contact angle drop. We will focus on the software set up and operation of the automated measurement in OneAttension as well as data analysis of the roughness corrected contact angle.
- [Enhancing Cryo-TEM Efficiency: Screening Negatively Stained Samples with Desktop STEM](https://www.nanoscience.com/webinars/enhancing-cryo-tem-efficiency-screening-negatively-stained-samples-with-desktop-stem/): Negative Stain imaging is a critical step in the single-particle cryo-EM workflow, allowing researchers to assess sample quality at room temperature before moving to complex cryo-preparation and imaging. Traditionally, this process requires a dedicated TEM and an experienced operator to handle the imaging.
- [Advancing Battery Technology with SEM/EDS: Optimizing Quality and Performance](https://www.nanoscience.com/webinars/advancing-battery-technology-with-sem-eds-optimizing-quality-and-performance/): As the world shifts towards electric vehicles and renewable energy, understanding and improving battery materials is more crucial than ever for enhancing performance and ensuring safety. Scanning Electron Microscopy (SEM) combined with Energy Dispersive Spectroscopy (EDS) offers a powerful window into the microstructures and elemental compositions of key battery components, driving innovation in both R&amp;D and production.
- [Innovative Drug Delivery Systems for Wound Healing Using Electrospinning](https://www.nanoscience.com/webinars/innovative-drug-delivery-systems-for-wound-healing-using-electrospinning/): Chronic wounds and wound infections are a major problem for the society and novel treatment approaches are being developed to improve the current gold standard in wound care.
- [Going Full-Tilt: Dynamic Contact Angle Measurements with a Tilting Cradle | Tensiometry Masterclass Session #1](https://www.nanoscience.com/webinars/going-full-tilt-dynamic-contact-angle-measurements-with-a-tilting-cradle-tensiometry-masterclass-session-1/): In the first edition of the Tensiometry Masterclass Series, we will be shifting our perspective, quite literally, with tilting contact angle measurements on the Theta Flow/Flex Optical Tensiometer. Dynamic contact angle measurements through droplet tilting are a great way to assess the efficacy, quality, and history of coatings that have performance properties dependent on their wettability: such as liquid-repellent/phobic surfaces, self-cleaning, anti-microbial, bonding, etc. While this experiment is deceptively simple, there are important considerations for a successful measurement. In this masterclass, we will go through a dynamic contact angle measurement using the tilting cradle, manually rotating the entire optical tensiometer while capturing droplet images as the sample and droplet tilts. We will focus on key parameters in the setup and the automated hardware/software features in OneAttension to enhance the accuracy and reproducibility of this measurement.
- [Electrospinning in Industry: Versatile and Scalable Nanomaterial Production](https://www.nanoscience.com/webinars/electrospinning-in-industry-versatile-and-scalable-nanomaterial-production/): Electrospinning, with its ability to process a diverse range of materials and produce customizable form factors, has emerged as a versatile technique in industrial-scale materials production. Commercial electrospinning equipment stands out for its exceptional versatility and scalability, offering a spectrum of processing options from single-needle to 5000+ needle configurations or needleless techniques. This flexibility enables the production of nanomaterials tailored for various applications spanning from advanced medical devices and biomaterials to high-performance textiles, energy storage, and filtration media. Moreover, the high throughput capability of commercial electrospinning ensures efficient production of desired medical devices and nanomaterials/biomaterials at the industrial scale. This webinar presents an example of a clear scalability pathway and current production throughput capabilities using common industry polymers and the Fluidnatek professional electrospinning equipment. The data presented supports the future potential of commercial electrospinning to reshape the landscape of medical device and materials manufacturing, offering innovative production solutions with substantial versatility and scalability.
- [Enhancing Elemental Analysis with Real-Time Mapping: Phase Identification Using ChemiSEM &#038; Phase Mapping](https://www.nanoscience.com/webinars/enhancing-elemental-analysis-with-real-time-mapping-phase-identification-using-chemisem-phase-mapping/): Elemental analysis is a crucial aspect of material characterization, but traditional methods can be time-consuming and complex. ChemiSEM revolutionizes this process by utilizing machine learning and ultrafast signal processing to provide real-time elemental maps over live SEM images. This technology offers pixel-by-pixel analysis, delivering instant insights into the sample&#039;s composition. The ability to visualize elemental distribution in real-time significantly enhances productivity and accuracy in various applications.
- [Assessing Stability and Material Compatibility of Biopharmaceutical Formulations through QCM-D Analysis](https://www.nanoscience.com/webinars/assessing-stability-and-material-compatibility-of-biopharmaceutical-formulations-through-qcm-d-analysis/): Get an early indication of potential incompatibilities and identify ways to mitigate.
- [Conference Presentation – Electrospinning in Industry: Versatile and Scalable Nanomaterials Production](https://www.nanoscience.com/webinars/conference-presentation-electrospinning-in-industry-versatile-and-scalable-nanomaterials-production/): Electrospinning is a fiber formation technique used to generate fibers with diameters ranging from 20 nm to 10 µm. It has become popular in the industrial community as it is a single step process capable to use materials like polymers, metals, ceramics, and other additives. The capability to fine tune sample microstructures and overall physical and chemical properties opens up the possibilities to be used in different applications including medical devices, drug delivery, energy storage, tissue engineering and filtration.
- [Screening of the Binding Affinity of Serum Proteins to mRNA-LNPs by QCM-D ](https://www.nanoscience.com/webinars/screening-of-the-binding-affinity-of-serum-proteins-to-mrna-lnps-by-qcm-d/): Join us to hear from Federica Sebastini, who earned her PhD in chemistry from the University of Reading, UK, in 2014. She is currently working as a Tenure Track Assistant Professor at the Department of Pharmacy, University of Copenhagen.
- [Overcoming Surface Roughness in Contact Angle Measurements](https://www.nanoscience.com/webinars/overcoming-surface-roughness-in-contact-angle-measurements/): When using contact angle measurements to analyze the wettability of a surface, certain assumptions are often made about the sample: the surface is unreactive, rigid, insoluble, chemically homogenous, and smooth. While reasonable inferences can be made about a surface’s physical and chemical characteristics, some roughness will always be present. As we move away from ideal-smooth surfaces to real-world samples, the topography of a sample surface can significantly alter the measured contact angle, affecting how liquids adhere. And depending on the surface’s function, this may be helpful or detrimental to its bottom-line. Therefore, accounting for surface roughness during optical tensiometry measurements is critical to differentiate the effects of surface chemistry and physical topography. This is relevant to numerous fields where wettability and adhesion are fundamental for operation, such as medical device biocompatibility, printing on paper, structural integrity in additive manufacturing, and surfaces after abrasive processing.
- [How Surface Wettability Affects Biomaterials and Biomedical Devices ](https://www.nanoscience.com/webinars/how-surface-wettability-affects-biomaterials-and-biomedical-devices/): Wettability is an important material property that affects a material’s response to its surrounding environment. For biomedical devices and biomaterials, wettability determines how the material will interact with proteins, cells, and bacteria. &nbsp;
- [Electrospinning Innovations in Commercial Medical Devices](https://www.nanoscience.com/webinars/electrospinning-innovations-in-commercial-medical-devices/): Electrospinning has come to play a pivotal role in transforming wound healing and dressings, enhancing drug delivery systems for precise treatments, and providing significant contributions in tissue engineering and regenerative medicine. It has also found its application in creating implantable medical devices and fostering the development of biocompatible materials that are reshaping the medical device industry.
- [Assessing the Inflammatory Responses Induced by Biomaterials in Contact with Human Blood Using In Vitro Assays Including QCM-D](https://www.nanoscience.com/webinars/assessing-the-inflammatory-responses-induced-by-biomaterials-in-contact-with-human-blood-using-in-vitro-assays-including-qcm-d/): Biomaterials and nanoparticles (NPs) are used in a wide range of different health care applications from implants to dialysis membranes and cell carriers. Important for all types of biomaterial implants are their biocompatibility, i.e. how they are perceived when they come in contact with the body&#039;s tissues and fluids. However, most biomaterials and NPs are far from ideal and induce strong adverse reactions through activation of the blood&#039;s cascade system, i.e. the innate immune system (complement system) and the coagulation system leading to inflammation and thrombosis.
- [Elastin Based Nanofibers for Advanced Wound Care: Innovation Driven by Electrospinning](https://www.nanoscience.com/webinars/elastin-based-nanofibers-for-advanced-wound-care-innovation-driven-by-electrospinning/): The extracellular matrix (ECM) is a network of structural proteins that support cells and enhance tissue mechanical properties. Elastin, a crucial ECM protein, gives tissues elasticity and resilience. However, it is not replenished in the body, leading to tissue degeneration. To address this, we developed customizable biomaterials to counteract age- and injury-related decline in skin function. We processed elastin using a scalable method and created composite elastin/collagen nonwoven materials through electrospinning and crosslinking. These materials contained up to 90% elastin, reducing nanofiber stiffness and increasing porosity. They were absorbable, non-toxic, and suitable for cell culturing. Endotoxin levels were low, and the material caused no adverse tissue reactions after implantation. This work provides a versatile platform for large-scale, cost-effective production of elastin-based nonwovens for various biomedical applications.
- [Sample Preparation for SEM by Ion Milling](https://www.nanoscience.com/webinars/sample-preparation-for-sem-by-ion-milling/): Sample preparation usually begins with mechanical grinding and polishing. During this process, the grinding and polishing creates a deformed or amorphous layer on the surface called the Beilby layer. This layer can disrupt scanning electron microscopy (SEM) measurements and blurs the diffraction pattern of the sample. Different ways to remove the amorphous layer are refining mechanical polishing, chemical etching, and electropolishing. These techniques are time consuming, material dependent, difficult processes, and sometimes unsuccessful. A promising technique that has been developed is ion polishing and milling. These techniques are less sensitive to the microstructure and chemical composition. By adjusting parameters such as the ion’s energy and angle of milling, users can control the milling rate and depth. The Ion Mill can be used to reveal features hidden under the amorphous layer and give researchers the ability to make precise measurements, EBSD measurements, and a view a true polishing of a cross section under the SEM.
- [Empowering Nanoscale Discovery: Introducing Phenom Desktop STEM](https://www.nanoscience.com/webinars/empowering-nanoscale-discovery-introducing-phenom-desktop-stem/): The STEM holder for the Phenom Pharos Desktop SEM unlocks advanced transmission imaging capabilities. With its dedicated detector, the holder offers bright field, dark field, and high-angle annular dark field imaging at resolutions less than 1nm. Seamlessly integrated within the user-friendly Phenom interface, these enhanced capabilities empower both novice and experienced users to obtain exceptional data.
- [Fueling Progress: SEM Techniques for Fuel Cell Applications](https://www.nanoscience.com/webinars/fueling-progress-sem-techniques-for-fuel-cell-applications/): Scanning Electron Microscopy (SEM) is an indispensable tool in the realm of fuel cell technology, offering a window into the intricate micro- and nanoscale structures that dictate performance and efficiency. Through SEM, scientists gain important insights into components such as proton exchange membranes (PEMs), gas diffusion layers (GDLs), and catalysts, enabling a thorough understanding of morphology, composition, and interfacial interactions. By delving into the subtle details of material surfaces, SEM facilitates the optimization of these crucial components, leading to enhanced energy conversion, improved durability, and ultimately, the advancement of clean and sustainable fuel cell applications.
- [Confidence in Cleanliness: Automated SEM for Analysis of Manufactured Parts](https://www.nanoscience.com/webinars/confidence-in-cleanliness-automated-sem-for-analysis-of-manufactured-parts/): As specifications get tighter and demand increases on manufactured components, manufacturers are depending more on a comprehensive cleanliness analysis to increase workflow and decrease field failures. Although, current methodologies may provide a snapshot of the cleanliness of a part, testing such as gravimetric, or optical microscopy do not provide the full picture of what the “Killer Particles” are and where they are coming from.
- [Optimizing Battery Materials with Force Tensiometer for Efficient Manufacturing](https://www.nanoscience.com/webinars/optimizing-battery-manufacturing-with-the-sigma-700-force-tensiometer/): With the increased reliance on batteries for renewable energy power consumption, the development and demand for batteries will continue to rise. Outside of pure battery performance, the manufacturing process can bottleneck bringing battery materials to market. For a variety of steps in the battery manufacturing process, force tensiometry can provide solutions for materials optimization and quality control.
- [QCM-D Technology: From Fundamental Membrane Biophysics to Translational Applications](https://www.nanoscience.com/webinars/qcm-d-technology-from-fundamental-membrane-biophysics-to-translational-applications/): The quartz crystal microbalance-dissipation (QCM-D) technique has emerged as one of the most powerful bioanalytical tools to characterize biological phenomena, especially at lipid membrane interfaces.
- [Tiny Residue, Big Clues: Forensic Science with Automated SEM Analysis](https://www.nanoscience.com/webinars/tiny-residue-big-clues-forensic-science-with-automated-sem-analysis/): The importance of forensic science in investigative and legal procedures demands that potential evidence is properly analyzed. With a wide range of physical evidence to analyze, including paint, fibers, and gunshot residue (GSR), forensic scientists face the challenge of investigating hundreds of thousands of criminal cases every year. In this webinar, we will explore how scanning electron microscopy (SEM) can provide vital solutions for forensic scientists; specifically, how automated SEM with energy dispersive X-ray spectroscopy (EDS) revolutionizes GSR particle analysis.
- [2023 QSense Omni Introduction Event](https://www.nanoscience.com/webinars/2023-qsense-omni-introduction-event/): We are excited to introduce our next-generation premium QCM-D instrument, QSense Omni, that is designed to meet your needs for ease of use, flexibility, automation, and reliable results.
- [Advancement of Tissue Engineering Using Desktop SEM](https://www.nanoscience.com/webinars/advancement-of-tissue-engineering-using-desktop-sem/): Tissue engineering is a progressively advancing field focusing on biological substitutes to improve or restore functions to damaged tissues or organs in the body. Many of these substitutes are found helping patients with burn wounds, diabetic wounds, diseased tissues, and many more. With such advancements, having a strong understanding of the tissue’s structures will help determine what the longevity is with these tissue substitutes.
- [How Clean is Your Surface? Surface Free Energy as a Measure of Cleanliness](https://www.nanoscience.com/webinars/how-clean-is-your-surface-surface-free-energy-as-a-measure-of-cleanliness/): In manufacturing and fabrication processes, contamination can impede downstream processing and result in increased production times and material waste. Therefore, it is essential to track the cleanliness of surfaces throughout manufacturing.
- [What is ParticleX? Automated Particle Analysis for Scanning Electron Microscopy](https://www.nanoscience.com/webinars/what-is-particlex-automated-particle-analysis-for-scanning-electron-microscopy/): Routine and manual SEM characterization can be a tedious labor that leaves little room to perform additional analysis and reporting without consuming more time. To remedy these issues and add a level of consistency for data collection, automated processes for quality control have been implemented with SEMs to provide a complete analysis of particle morphology, size, and chemical composition.
- [If SEM, Then Script: Python Coding for Scanning Electron Microscopes](https://www.nanoscience.com/webinars/if-sem-then-script-python-coding-for-scanning-electron-microscopes/): This upcoming webinar will showcase the innovative application of Python programming to control the Phenom Desktop SEM. Attendees will learn how Python can be used to automate the SEM imaging process, enabling faster, less user biased, and more efficient data collection. The webinar will provide an overview of the Phenom Desktop SEM and its capabilities, as well as a step-by-step guide on how to set up and use Python to control the instrument. Participants will gain a comprehensive understanding of how to leverage Python scripting to improve their SEM workflows. With the increasing demand for automated and high-throughput SEM imaging, this webinar is a must-attend for anyone looking to enhance their SEM capabilities through the power of Python programming. Join us to explore the intersection of scanning electron microscopy with computer programming and discover how this innovative approach can transform your research and analysis.&nbsp;
- [Electrospinning Scalability of BioTextiles for Tissue Engineering &amp; Medical Applications](https://www.nanoscience.com/webinars/electrospinning-scalability-of-biotextiles-for-tissue-engineering-medical-applications/): Electrospinning is a rapidly growing method for producing nonwoven materials that mimic the extracellular matrix of the&nbsp;in vivo&nbsp;environment. This technique allows for the use of environmentally friendly polymers and the integration of thermally sensitive additives to create biotextiles for medical purposes.
- [Surface Evaluation for Good Wettability and Coating Adhesion from Biolin Scientific](https://www.nanoscience.com/webinars/surface-evaluation-for-good-wettability-and-coating-adhesion-from-biolin-scientific/): Good wettability is a prerequisite for good coating adhesion. Different types of surface treatments, such as plasma, laser texturing, or flame treatment are used to improve the wettability of the surface and subsequently the coating adhesion.
- [Characterizing Molecular Interactions of Food Ingredients at Various Stages of Processing with QSense QCM-D](https://www.nanoscience.com/webinars/characterizing-molecular-interactions-of-food-ingredients-at-various-stages-of-processing-with-qsense-qcm-d/): Every food product currently available to human beings has some involvement of food science. Understanding the science of food is vital for meeting the nutritional demands of growing populations while minimizing wasteful and unsustainable processes. &nbsp;
- [Morphological and Compositional Analysis of Battery Materials](https://www.nanoscience.com/webinars/morphological-and-compositional-analysis-of-battery-materials/): With the increasing demand for clean and sustainable energy, there is an ongoing need for more efficient and reliable energy storage systems. At the foundation of these systems, R&amp;D and production of battery materials is focused on optimization of composition, structure, and fabrication methods to improve device performance, safety, feasibility, and sustainability.
- [How Clean is Your Surface? Contact Angles as a Measure of Cleanliness](https://www.nanoscience.com/webinars/how-clean-is-your-surface-contact-angles-as-a-measure-of-cleanliness/): Is your surface clean? Is surface cleanliness critical to your fabrication or manufacturing process?
- [Leveraging the Power of Desktop SEMs for Drug Development](https://www.nanoscience.com/webinars/leveraging-the-power-of-desktop-sems-for-drug-development/): Drug development requires rapid data driven decisions to address the challenges in formulation and keep pace with the demand for higher therapeutic effectiveness. As drug development increasingly focuses on the nanoscale behavior of compounds, analytical techniques such as optical microscopy are falling short of delivering the data needed to investigate drug material efficacy. With the right tool, the physical characteristics of the API and excipient can be thoroughly and easily characterized. Scanning electron microscopes are versatile instruments that provide a vast range of data required for drug development, including high resolution surface imaging, particle sizing, morphological analysis, chemical composition, and API distribution analysis.
- [Dynamic Yet Reproducible: Advantages of Dynamic Contact Angle Measurements](https://www.nanoscience.com/webinars/dynamic-yet-reproducible-advantages-of-dynamic-contact-angle-measurements/): In this webinar we will demonstrate the superior nature of dynamic contact angle (CA) measurements for better understanding the wettability and related properties of a solid surface.
- [Totally Tubular! Electrospun Tubular Structures for Tissue Engineering](https://www.nanoscience.com/webinars/totally-tubular-electrospun-tubular-structures-for-tissue-engineering/): Tissue Engineering of tubular scaffolds such as artificial blood vessels, nerve conduits, or stents has become more commonplace with the advent of advanced functional materials. Electrospinning offers a unique way to process biocompatible polymers at lower temperatures enabling a wealth of new potential that was not previously available.
- [Advances in Automated Inclusion Analysis using Desktop SEM](https://www.nanoscience.com/webinars/advances-in-automated-inclusion-analysis-using-desktop-sem/): Industry demands are placing the pressure on Steel manufacturers to make higher quality and cleaner steel. Steel manufacturers are looking for tools that can assist in making the decisions needed to improve their steel making process and control nonmetallic inclusions.
- [Don&#8217;t Get It Twisted — Why Electrospun Fiber Alignment Matters for Tissue Engineering](https://www.nanoscience.com/webinars/dont-get-it-twisted-why-electrospun-fiber-alignment-matters-for-tissue-engineering/): Electrospinning has always provided the largest set of tools in engineering fibers for a variety of applications. The benefits of the technique are even more pronounced in tissue engineering, where controlling the various aspects of the fiber structure and morphology in a repeatable fashion is crucial for generating high-performance tissue scaffolds.
- [Observing Mixed Ionic-Electronic Transport in Redox-active Polymers](https://www.nanoscience.com/webinars/observing-mixed-ionic-electronic-transport-in-redox-active-polymers/): Redox-active polymers have promising applications in electronics and energy storage due to the polymer’s tunable conductivity and redox activity. For example, the conductivity of poly(3-hexylthiopene) (P3HT) is heavily dependent upon the doping level and the dopant type. This feature becomes especially important when considering P3HT or similar conjugated polymers for devices that require switching between electronic states (conductive vs insulating).
- [Electrospun Micro and Nanofibers for Medical Applications](https://www.nanoscience.com/webinars/electrospun-micro-and-nanofibers-for-medical-applications/): Electrospinning has become an ideal technique for generating samples for tissue engineering as it is able to reproducibly fabricate micro or nanofibers that biomimic the structural and physicochemical properties of extracellular matrix from native tissues. The large surface area offered by electrospun fibers, the cost-effectiveness of the technique, and the ability to track important parameters such as real-time sample thickness during processing make electrospinning an attractive choice for academic as well as industrial R&amp;D.
- [Using EQCM-D in situ to Monitor Evolution of the Solid Electrolyte Interphase &#038; Characterize Electrode Materials](https://www.nanoscience.com/webinars/using-eqcm-d-in-situ-to-monitor-evolution-of-the-solid-electrolyte-interphase-characterize-electrode-materials/): This webinar discusses the critical problems that Electrochemical Quartz Crystal Microbalance with Dissipation monitoring (EQCM-D) can help resolve for optimizing the Solid Electrolyte Interphase (SEI) and related electrode chemistries for improved rechargeable battery technologies.
- [Bringing 2 nm resolution and low accelerating voltages to the tabletop SEM — Introducing the Phenom Pharos G2](https://www.nanoscience.com/webinars/bringing-2-nm-resolution-and-low-accelerating-voltages-to-the-tabletop-sem-introducing-the-phenom-pharos-g2/): Building upon the compact design of the world’s best-selling desktop SEM, the Pharos G2 system allows users to harness the full power of a FE-SEM without the hassles and environmental constraints of a floor-model unit. Thanks to the field-emission source, the Pharos G2 can also image charging or beam-sensitive samples faster and easier than ever before. From polymers to nanoparticles, the Pharos G2 can provide exceptionally clear images of nearly any material without damaging important features or microstructures.
- [Introducing the Theta Flow for Enhancing Contact Angle Data Quality and Workflow](https://www.nanoscience.com/webinars/introducing-the-theta-flow-for-enhancing-contact-angle-data-quality-and-workflow/): Have you ever considered how contact angle measurements can vary based on different operators sharing an instrument, variable environmental conditions, or manual adjustments to hardware settings?
- [Understanding the Physical and Mechanical Properties of Flexible Biopolymers](https://www.nanoscience.com/webinars/understanding-the-physical-and-mechanical-properties-of-flexible-biopolymers/): Biopolymers are essential building blocks of life. The structure of one biopolymer is no mystery – DNA’s double helix is one of the most famous structures in the world. But DNA is not the only biopolymer in our bodies. The last two decades have made it increasingly clear that flexible biopolymers, such as intrinsically disordered proteins and polysaccharides, also play many crucial roles in the organization and functions of our cells and tissues. Join us for a&nbsp;webinar&nbsp;on Wednesday, January 13th as we explore techniques that help us to better understand these important pieces of our biology.
- [Real-time Insight into Polymer Adsorption and Conformation](https://www.nanoscience.com/webinars/real-time-insight-into-polymer-adsorption-and-conformation/): Often the mechanistic properties of polymers are just as important as their chemical contributions to their myriad of applications. For example, whether a polymer swells or shrinks in response to external stimuli such as salt or pH will play a large role in the degree to which cells adhere, petroleum can be liberated from a surface, or the efficiency of a degradation process. While some techniques can detect either mass or structural changes of an adsorbed polymer layer, very few can detect both simultaneously and in real-time. Quartz crystal microbalance with dissipation (QCM-D) is one such technique.
- [How Excipients, Surfaces and Formulation Conditions Affect Therapeutic Proteins](https://www.nanoscience.com/webinars/how-excipients-surfaces-and-formulation-conditions-affect-therapeutic-proteins/): During the manufacturing and delivery process therapeutic proteins encounter several surfaces and consequently, face the risk of aggregation. There are several factors that can induce aggregation, such as temperature, shipping, storage, and physical stress. Aggregation can lead to loss of immune response or unwanted cross-reactivity and is typically remediated via addition of excipients to stabilize a formulation.
- [Now that we found Surface Free Energy what are we going to do with it?](https://www.nanoscience.com/webinars/now-that-we-found-surface-free-energy-what-are-we-going-to-do-with-it/): Surface free energy (SFE) is a commonly measured parameter that tells us about the polar and dispersive properties of a solid. However, once this value is obtained typical follow-up questions include:
- [Better, Faster &#038; Remotely Controllable – A Demo Showing the Power of Modern Desktop SEM](https://www.nanoscience.com/webinars/better-faster-remotely-controllable-a-demo-showing-the-power-of-modern-desktop-sem/): Join us for a webinar and demonstration showcasing the power of desktop scanning electron microscopy. Thermo Scientific’s&nbsp;Phenom desktop SEM&nbsp;is the world’s best selling SEM, and after 15 years of continuous development the 6th&nbsp;generation of these systems takes yet another leap forward. Innovations include more powerful imaging, enhanced automation capabilities, and a brand new user interface geared towards remote operation. Learn why these features&nbsp;make the Thermo Scientific Desktop SEMs the instrument of choice for labs the world over.
- [Better Understand the “C” of the CMP process](https://www.nanoscience.com/webinars/better-understand-the-c-of-the-cmp-process/): On-Demand Webinar: Analyze chemical and surface interactions affecting CMP with Quartz Crystal Microbalance with Dissipation (QCM-D)As semiconductor process nodes keep shrinking, new materials and fabrication strategies must be implemented. New materials mean ever evolving strategies and the Chemical Mechanical Planarization or Polishing (CMP) process is not immune to these increased demands.
- [How do we stop the next pandemic from an unknown virus?](https://www.nanoscience.com/webinars/how-do-we-stop-the-next-pandemic-from-an-unknown-virus/): Over the past decades, we have experienced several viral outbreaks, such the Swine flu, Ebola, Zika, and now most recently, COVID-19. Viral outbreaks will undoubtedly continue to occur, and it is not unlikely that future outbreaks may come from either unknown or understudied viruses. As vaccines often take years to develop, a different approach may be needed to prepare and respond to future outbreaks and pandemics.
- [QCM-D as a tool to study the binding of viruses](https://www.nanoscience.com/webinars/qcm-d-as-a-tool-to-study-the-binding-of-viruses/): Our guest speaker, Gustaf Rydell, researcher at Sahlgrenska University Hospital, will describe how they have used QCM-D to study the interaction between virus particles and membrane associated glycolipids. Attachment to the plasma membrane is an important step initiating viral infection of a target cell as illustrated by norovirus. This virus causes the winter vomiting disease and binds to ABO blood group active carbohydrates that are absent in 20% of the population in northern Europe. These so-called secretor negative individuals are therefore resistant to infections with the most common strains of the virus. He will describe how they have studied the binding process of the virus using QCM-D and other techniques to understand how norovirus initiates infection. He will also describe studies they have done with other viruses and present some current research topics to discuss what information biosensors could provide.
- [Food Ingredient Formulation Development with Novel Real-time Technique](https://www.nanoscience.com/webinars/food-ingredient-formulation-development-with-novel-real-time-technique/): Nanoscience Instruments is proud to host&nbsp;Dr. Alireza Abbaspourrad&nbsp;and Dr. Younas Dadmohammadi from Cornell University as they present some of their novel findings on bioactive incapsulation and self life studies in a free webinar on August 27th.
- [To Adhere or Not to Adhere – That is the Question](https://www.nanoscience.com/webinars/to-adhere-or-not-to-adhere-that-is-the-question/): The ability of two materials to adhere to each other is dictated by several variables, including topography, cleanliness, and wettability. For example, a coat of paint may not stick to a surface without the surface first being treated with a primer. The adhesion between the final top coat and the underlying surface is greatly increased due to high compatibility of the primer with the paint. Conversely, design of water repellent surfaces often involves an innately hydrophobic material whose properties are enhanced by topographical features. Many techniques are available to determine adhesion (or lack thereof) to a surface, such as static contact angle, advancing and receding contact angle, surface free energy, and tilting angle. Additionally, roughness plays a key role in both producing and obscuring the properties of a coating or surface.
- [Surface and Interfacial Tension: How, What and Why?](https://www.nanoscience.com/webinars/surface-and-interfacial-tension-how-what-and-why/): Join Nanoscience Instruments on May 27th for a webinar on Surface and Interfacial Tension measurements utilizing the Attension Theta Flex.
- [Characterization of surfaces and surface reactions in energy storage](https://www.nanoscience.com/webinars/characterization-of-surfaces-and-surface-reactions-in-energy-storage/): The use of energy storage systems, such as Li-ion batteries, has significantly increased in recent decades, on both the grid-scale and individual consumer levels. With the global shift to renewable energy, such as wind and solar power, the need for energy storage will continue to rise. Researchers are trying to optimize efficiency, cost, and environmental impact of these devices.
- [Next Generation Nanofibers for Air Filtration](https://www.nanoscience.com/webinars/next-generation-nanofibers-for-air-filtration/): As the demand for air filtration materials has increased globally, especially in the wake of an aerosol-based global pandemic, alternative sources of filter fibers are now an area of significant focus. Electrospun nanofiber filters represent a promising candidate due to the enhanced fine particle removal, versatile fiber functionalization, and ease of filter regeneration. However, to realize these properties, proper control over environmental conditions during electrospinning tethered to efficient and reliable methods for analyzing fiber structural properties are imperative.
- [VitroJet: Revolutionizing CryoEM Sample Prep](https://www.nanoscience.com/webinars/vitrojet-revolutionizing-cryoem-sample-prep/): The increasing demand of CryoEM for producing high resolution 3D structures is hampered by sample preparation, a major bottle neck in the CryoEM workflow. Current commercial sample preparation techniques rely on methods that are limited in efficiency and reproducibility. Despite innovation in microscope technology, the unreliable method of plunge freezing with subsequent post clipping still remains common practice. The good news is that the VitroJetTM&nbsp;from CryoSol-World has been developed to introduce several controllable techniques and combine them into one device with minimal operator intervention.1
- [Characterize materials and products for Additive Manufacturing](https://www.nanoscience.com/webinars/characterize-materials-and-products-for-additive-manufacturing/): The Additive Manufacturing (3D Printing) market is rapidly growing and expected to nearly triple within the next six years, surpassing 23 billion dollars in 2026 from 8 billion dollars in 2018. The increasing developments in technologies and materials used in additive manufacturing are creating opportunities, innovations, and excitement across the industry.
- [Combine techniques to unlock potential: QSense modules and accessories](https://www.nanoscience.com/webinars/combine-techniques-to-unlock-potential-qsense-modules-and-accessories/): Complementary techniques are often necessary when investigating complex surface phenomena. Combining these techniques in the same setup for simultaneous in-situ measurements offers a very promising approach.
- [Topography and Contact Angle Characterization with Attension Theta Flex](https://www.nanoscience.com/webinars/topography-and-contact-angle-characterization-with-attension-theta-flex/): Join Nanoscience Instruments for an overview of the Attension Theta Flex with the topography module. This webinar will focus on how surface roughness and wettability affect the biocompatibility of implant materials.
- [Enhancing EOR with High-Pressure Contact Angle Measurements](https://www.nanoscience.com/webinars/enhancing-eor-with-high-pressure-contact-angle-measurements/): Enhanced Oil Recovery&nbsp;requires analysis and methods undertaken at the reservoir conditions. The high pressures and temperatures of the reservoir affect all aspects of the surfactants: the interfacial tension, wetting and foam properties. The Attension Theta Flex High-Pressure chamber replicates these harsh conditions of an oil field. Combined with the intuitive OneAttension software, and easy-to-use high-pressure chamber system, you’ll be able to measure contact angle interfacial rheology, pendant drop plus more.
- [Expert Sample Preparation for High Quality Image Results Webinar](https://www.nanoscience.com/webinars/expert-sample-preparation-for-high-quality-image-results-webinar/): Scanning Electron Microscopes&nbsp;(SEM) and Transmission Electron Microscopes (TEM) rely heavily on the suitable sample preparation techniques. Ten more minutes spent on sample preparation leads to hundred times better images.
- [Creating Drug Delivery Systems: Targeted Release with Electrospun Fibers and Electrosprayed Particles](https://www.nanoscience.com/webinars/creating-drug-delivery-systems-targeted-release-with-electrospun-fibers-and-electrosprayed-particles/): Join Dr. Francisco Chaparro of Nanoscience Instruments as he presents how electrospinning instrumentation is being used in the Drug Delivery applications.
- [Surfactants in Cleaning and Cosmetics](https://www.nanoscience.com/webinars/surfactants-in-cleaning-and-cosmetics/): Dr. Matthew Dixon, Product Manager at Nanoscience Instruments will present an overview of the QSense, a quartz crystal microbalance that is being utilized in industry to evaluate surfactant and cleaning performance. The QSense&nbsp;enables analysis of molecular interactions and surface properties in real-time. Based on established and powerful quartz crystal microbalance technology, QSense®&nbsp;gives you vast exploration and experimentation capabilities making it easy for you to find answers to the questions that need asking.