Integrated Cryo-FLM System
Reduce transfer steps and improve sample yield with integrated cryo-CLEM
METEOR overcomes the challenges in the current cryogenic electron tomography (cryo-ET) workflow by providing the capability to perform in situ fluorescence light microscopy (FLM) in your cryo focused ion beam (FIB)/ scanning electron microscope (SEM) chamber. Not only does it reduce the number of transfer steps between microscopes, protecting the fragile sample from unnecessary contamination, it will also allow you to confirm the presence of the region of interest (ROI) in the lamella directly after FIB milling. METEOR is highly adaptable to your current workflow and works well with your transfer systems and sample holders, making it easy to adopt.
METEOR can ensure an efficient workflow and increased sample yield for downstream acquisition of high resolution three dimensional biological structures in their near-native cellular environment. It’s a powerful tool that can be applied to a wide range of research areas including microbiology, neurosciences, immunology, virology, developmental, cell and molecular biology.
Use the METEOR from Delmic to:
- Increase sample yield. Target your ROIs and correlate better and more effectively with the integrated FLM. Reduce transfer steps and thereby sample damage.
- Optimize your workflow. Save time and work more efficiently by having both FLM and FIB in the same microscope.
- Boost productivity. Produce high quality lamellae more easily. Obtain insight into your biological system through getting useful tomography data more quickly.
- Improve cost efficiency. Use your cryo TEM time more effectively on useful lamellae. Remove the need for a separate cryo FLM dedicated solely to ROI finding.