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Fluidnatek® LE-500

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Product Brochure
Fluidnatek® Electrospinning & Electrospraying System

Fluidnatek LE-500

Product Overview

Instrument of Choice for Pilot Scale Volumes & Beta-release Commercialization

For scientists and engineers needing pre-production volumes and production-quality materials. The LE-500 can be used in advanced development projects, beta-release, and other pre-market introduction activities.

Maximize Production

Horizontal, vertical, and angled sample processing enables high throughput and fabrication of complex structures

Full Environmental Control

Unique HEPA-filtered unit provides control over increasing or decreasing temperature (18-45°C), relative humidity (10-80%), and airflow (90-180 m3/h)

Needle-based or Needle-less

Develop samples with needle-based or needle-less emitters, or both simultaneously

Pilot-scale Production

Process up to 8 Liters of solution with up to 370 needles to generate pilot-scale quantities of electrospun or electrosprayed material

LE-500 Features

The LE-500 tightly controls humidity and temperature, measures sample thickness in real-time, and supports the use of a roll-to-roll collector. In addition, users can employ up to 370 emitters to produce electrospun fibers or electrosprayed particles, making this unit a powerful tool for product commercialization. Multiple optional upgradable features to improve production can also be implemented at any time. It employs the same core technology as Bioinicia’s full GMP production plant. This unit is capable to be ISO-13485 for medical devices and can operate at ISO-7 clean conditions.

  • Pilot-scale production unit for product commercialization
  • Touchscreen controls
  • Primary high voltage power supply for the emitter
  • Secondary high voltage power supply for the collector
  • Semi-continuous liquid feeding system
  • Remote Ethernet access
  • Automated variable target distance (emitter to collector)
  • Temperature and humidity display
  • Single-phase multi-emitter spinning head
  • Safety shut-off switches in the access door
  • Actively regulated exhaust system

Talk to an Instrumentation Specialist Today!

Fluidnatek LE-500

Optional Upgradeable Features

  • Environmental capacity to tightly control temperature (18-45°C), relative humidity (10-80%) and airflow (90-180 m3/h)
  • Metrology system to measure thickness and density area in real time
  • Secondary stage with independent voltage to process two solutions at the same time
  • Multi-needle system and/or slit injector (needle-less sample process)
  • High definition process data hub to monitor 20+ process parameters
  • Needle translation to improve sample homogeneity and thickness
  • Rotating collector (drums, discs, mandrels)
  • Roll-to-roll semi-continuous collecting system
  • Large solution reservoirs to increase throughput
  • Syringe heating (30-120°C)
  • UV-C lamps
  • Gas-assisted electrospinning head
  • Inlet and outlet HEPA filters
Videos & Demos

LE-500 Videos & demos

See Available Configurations

LE-500 Accessories

Fluidnatek equipment is extremely modular, enabling you to choose your configuration or upgrade at any time with the wide range of accessories and tools, including:

Environmental Control Unit (ECU)

  • Temperature from 18ºC to 45ºC
  • Relative humidity from 10% to 80%
  • HEPA filtration
  • Air flow control from 90 to 180 m3/h
  • Actively regulated exhaust system
  • Inert atmosphere capable


  • Single-phase
  • Coaxial (core-shell)
  • Triaxial
  • Multi-needle— single phase (with and without field deflectors)
  • Multi-needle— coaxial
  • Tubeless dispensing system
  • Slit Injector (needle-less)

High Voltage Options

  • Needle voltage
  • Collector voltage
  • Bipolar voltages
  • Secondary spinning stage


  • Flat Plate
  • Rotating Drum, Mandrel and Disk
  • Roll-to-roll and Conveyor belt
  • Fiber yarn collection module

Improving Sample Consistency

  • Taylor cone camera
  • Solvent gas jacket
  • Gas-assisted electrospinning
  • Actively regulated exhaust system

Needle Translation

  • Y-axis automated linear emitter motion
  • Z-axis automated regulation of needle distance
  • Flexible articulated mounting arm


  • Data login
  • Multi-user level access
  • Recipes (standard and advanced)
  • High-definition process data hub
  • Audit trail
  • Batch control
  • Smart Server (Remote Access)

Solution Feeding Systems

  • Syringe pumps (single, dual, triple)
  • Twin channel syringe pumps
  • High-pressure four channel syringe pumps
  • Pressurized vessels
  • Peristaltic pump
  • Syringe heater

Metrology System

  • For sample thickness measurement
  • For sample thickness measurement and area density

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