Fluidnatek Knowledge base

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Electrospinning Innovations in Commercial Medical Devices

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Controlling the Orientation of Electrospun Nanofibers for Tissue Engineering

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Product Brochure
Fluidnatek® Electrospinning & Electrospraying System

Fluidnatek® LE-100

Product Overview

The ideal choice for scientists and engineers working on advanced development projects, where maximum experimental capabilities, tighter process control, and larger sample sizes are key.

Monitor Sample Thickness

A metrology system allows you to measure sample thickness in real time with a triggered shutoff system for achieving a specific thickness

cGMP Certifiable

Leading electrospinning & electrospraying technology for pharma and biomedical processes. Validation for cGMP processes through IQ/OQ/PQ documentation packages

Needle-based and Needle-less

Develop samples with needle-based or needle-less emitters, or both simultaneously

Full Environmental Control

Unique HEPA-filtered unit provides control over increasing or decreasing temperature (18-45°C) and relative humidity (10-80%) and airflow (90-180 m3/h)

LE-100 Features

The Fluidnatek LE-100 is the equipment of choice for GMP production of high-value particles and special 3D shaped fiber objects relevant to the biomedical and pharmaceutical industries. This unit can be used in advanced development projects, beta-release, and other pre-market introduction activities. Measuring thickness in real time for biomedical textiles and monitoring 20+ parameters during processing are two key capabilities this unit offers. The LE-100 can operate under sterile ISO-7 conditions and offers tight control over humidity (10-80%) and temperature (18-45°C) to increase sample consistency and reproducibility, making this a powerful tool for even the most stringent applications.

  • Advanced R&D development equipment
  • All parameters are controlled from a touchscreen panel
  • Primary high voltage supply (0 to +30kV)
  • Syringe pump
  • Remote Ethernet access
  • Variable target distance (emitter to collector)
  • Temperature and relative humidity display
  • Safety shut-off switches in access doors
  • Passive solvent exhaust system

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Fluidnatek LE-100

Optional Upgradeable Features

  • Environmental capacity to tightly control temperature (18-45°C), relative humidity (10-80%) and airflow (90-180 m3/h)
  • Metrology system to measure sample thickness in real time
  • Secondary stage with independent voltage to process two solutions at the same time
  • Multi-needle system and/or slit injector (needle-less sample process)
  • High-definition process data hub to monitor 20+ process parameters
  • Adjustable collector voltage (bipolar) power supply to improve deposition and/or optimize sample porosity
  • Second and third syringe pumps for co-axial and tri-axial sample development
  • Gas-assisted electrospinning head
  • Needle translation to improve sample homogeneity and thickness
  • Taylor cone visualization system
  • Rotating collector (drums, discs, mandrels)
  • Syringe Heating (30 to 120 ℃)
  • UV-C lamps
Videos & Demos

LE-100 Videos & demos

See Available Configurations

LE-100 Accessories

Fluidnatek equipment is extremely modular, enabling you to choose your configuration or upgrade at any time with the wide range of accessories and tools, including:

Environmental Control Unit (ECU)

  • Temperature from 18ºC to 45ºC
  • Relative humidity from 10% to 80%
  • Air flow from 90 m3/h to 180 m3/h
  • HEPA filtration
  • Actively regulated exhaust system

Dry Heating Unit (DHU)

  • Temperature from ambient conditions to 45ºC
  • Relative humidity from ambient conditions to less than 10%
  • Actively regulated exhaust system

Collectors

  • Flat Plate
  • Rotating Drum, Mandrel and Disk
  • Roll-to-roll
  • Dummy collector
  • Fiber yarn collection module

High Voltage Options

  • Needle voltage
  • Collector voltage
  • Bipolar voltages
  • Secondary spinning stage
  • Dummy collector

Emitters

  • Single-phase
  • Coaxial (core-shell)
  • Triaxial
  • Multi-needle— single phase (with and without field deflectors)
  • Multi-needle— coaxial
  • Tubeless dispensing system
  • Slit Injector (needle-less electrospinning)

Solution Feeding Systems

  • Syringe pumps (single, dual, triple)
  • Twin channel syringe pumps
  • Syringe heater

Needle Translation

  • X-axis automated scanning emitter motion
  • Y-axis automated linear emitter motion
  • Z-axis automated regulation of needle distance

Improving Sample Consistency

  • Taylor cone camera
  • Solvent gas jacket
  • Gas-assisted electrospinning
  • Actively regulated exhaust system
  • Metrology system for thickness measurement

Software

  • Data login
  • Multi-user level access
  • Recipes (standard and advanced)
  • High-definition process data hub
  • Audit trail
  • Batch control
  • Smart Server (Remote Access)

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