Quartz Crystal Microbalance with Dissipation (QCM-D)

QSense QCM-D technology and instrumentation enable analysis of molecular interactions and surface properties

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Sensors and sample handling system
Number of sensors 8 (4 parallel in flow) 4 1 1
Volume above each sensor ~ 15 μl ~ 40 μl ~ 40 μl ~ 40 μl
Minimum sample volume ~ 50 μl ~ 200 μl ~ 200 μl ~ 200 μl
Working temperature ± 0.02 *A 4-70 °C 15-65 °C 15-65 °C 20-45 °C
Minimum dispense volume 1μl*
Sensors Gold, SiO2, Ti and other metals, oxides, nitrides, steels, glasses, polymers, etc.
Measurement Characteristics
Time resolution < 100 data points per second < 100 data points per second < 100 data points per second 2 data points per second
Maximum mass sensitivity in liquid ~ 0.5 ng/cm2 C ~ 0.5 ng/cm2 C ~ 0.5 ng/cm2 C
Normal mass sensitivity in liquid ~ 1.8 ng/cm2 F ~ 1.8 ng/cm2 F ~ 1.8 ng/cm2 E ~ 1.8 ng/cm2
Maximum dissipation sensitivity in liquid ~ 0.04 x 10-6 C ~ 0.04 x 10-6 C ~ 0.04 x 10-6 C
Normal dissipation sensitivity in liquid ~0.1 x 10-6 F ~0.1 x 10-6 F ~0.1 x 10-6 E ~0.1 x 10-4
Software
Analysis software QSense Dfind QSense Dfind QSense Dfind
Output parameters Frequency, dissipation, modeled values of mass, thickness, and viscoelasticity. Frequency, dissipation, Sauerbrey mass
Import/export Excel, BMP, JPG, WMF, GIF, PCX, PNG, TXT
Hardware
Electronics unit (HxWxL in cm) 70x67x57 18x36x21 18x36x21 18x36x21
Chamber (HxWxL in cm) 70x67x57 12x23x34 5x10x15 5x10x15
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  • A The temperature stability depends on variations in how the ambient temperature affects the warming or cooling of the chamber.
  • B Smallest sample volume to pick up and dispense. Note that the smallest volume needed for measurement is 50 µl.
  • C Data from one sensor in single frequency mode. One data point collected every 5 seconds. The Sauerbrey relation is assumed to be valid.
  • E Data from multiple frequency modes (all harmonics). Four data points are collected within 1 second. The Sauerbrey relation is assumed to be valid.
  • F Data from all sensors in multiple frequency modes (all harmonics) are collected within 1 second. The Sauerbrey relation is assumed to be valid

All specifications are subject to change without notice.