All Application & Technical Notes

Nanoscience Instruments White Papers

Electrosprayed CDC cell distribution time

App Note | Technology: Electrospinning

Co-Spinning Fibers and Cells to Improve Infiltration

Improving Cell Infiltration in Electrospun Nanofibers It is common knowledge that in order to biomimic the extracellular matrix (ECM) structure, electrospun fibers can be created with fiber diameter ranging in the nano- to micro-scale. Meanwhile, cell infiltration into scaffolding material is usually limited by pore…

Glioma cells and aligned electrospun PCL fibers

App Note | Technology: Electrospinning

Cell Growth and Proliferation on Electrospun Scaffolds

Electrospun Scaffolding for Cell Growth and Tissue Engineering In any type of scaffolding material cell migration, proliferation and differentiation are a key parameter for the success of tissue engineering and regenerative medicine applications. The ability of electrospun scaffolds to biomimic the extracellular matrix (ECM) environment…

Electrospun tubular shaped scaffolds

App Note | Technology: Electrospinning

Biomimetic Mechanical Properties of Tissue Constructs

Electrospun Nanofiber Scaffolding for Blood Vessels One of the main goals of electrospun fibrous scaffolding is to completely biomimic the extracellular matrix (ECM) environment. This includes incorporating cells and sustaining their proliferation, having fiber orientation according to the structure being mimicked, allowing degradation of the…

Comparison of blood vessels with electrospun fibers

App Note | Technology: Electrospinning

Bioactive Incorporation into Spun Scaffolds

Electrospun Scaffolds that are Thermolabile Bioactive Scaffolding techniques such as 3D printing and melt electrospinning can resemble the extracellular matrix (ECM) environment, however, due to the high temperatures involved they do not allow the process of thermolabile bioactives. These high temperatures denature bioactives (e.g. proteins…

App Note | Technology: Electrospinning

Electrospun Grafts for Wound Healing

Regenerative Medicine Utilizing Electrospun Scaffolds for Wound Healing Imagine a world where no organ donors are needed; a world where any type of tissue can be artificially created and function as compared to native tissue without rejection or scar formation. Scientists and engineers are currently…

Processed SEM image of Particle

App Note | Technology: Scanning Electron Microscopy

Pharmaceutical Particle Characterization

Particle Analysis and characterization with the Scanning Electron Microscope (SEM) Understanding the physical characteristics of particles in dry powder materials is an essential aspect of drug product development. The particle size distribution of either active pharmaceutical ingredients (APIs) of excipients often has a significant impact…

Generic EDS of a bulk tablet.

App Note | Technology: Scanning Electron Microscopy

Pharmaceutical Deformulation

The Analytical Tools Needed for Deformulation of Pharmaceutical Imaging plays an integral role in the deformulation of any product. Separation and quantification of individual ingredients often require a suite of analytical instrumentation. The Phenom ProX desktop SEM with EDS is the ideal tool for accurately…

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