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App Note | Technology: Electrospinning
Improving Cell Infiltration in Electrospun Nanofibers It is common knowledge that in order to biomimic the extracellular matrix (ECM) structure, electrospun fibers can be created with fiber diameter ranging in the nano- to micro-scale. Meanwhile, cell infiltration into scaffolding material is usually limited by pore…
App Note | Technology: Electrospinning
Electrospun Scaffolding for Cell Growth and Tissue Engineering In any type of scaffolding material cell migration, proliferation and differentiation are a key parameter for the success of tissue engineering and regenerative medicine applications. The ability of electrospun scaffolds to biomimic the extracellular matrix (ECM) environment…
App Note | Technology: Electrospinning
Electrospun Nanofiber Scaffolding for Blood Vessels One of the main goals of electrospun fibrous scaffolding is to completely biomimic the extracellular matrix (ECM) environment. This includes incorporating cells and sustaining their proliferation, having fiber orientation according to the structure being mimicked, allowing degradation of the…
App Note | Technology: Electrospinning
Electrospun Scaffolds that are Thermolabile Bioactive Scaffolding techniques such as 3D printing and melt electrospinning can resemble the extracellular matrix (ECM) environment, however, due to the high temperatures involved they do not allow the process of thermolabile bioactives. These high temperatures denature bioactives (e.g. proteins…
App Note | Technology: Electrospinning
Regenerative Medicine Utilizing Electrospun Scaffolds for Wound Healing Imagine a world where no organ donors are needed; a world where any type of tissue can be artificially created and function as compared to native tissue without rejection or scar formation. Scientists and engineers are currently…
App Note | Technology: Scanning Electron Microscopy
Particle Analysis and characterization with the Scanning Electron Microscope (SEM) Understanding the physical characteristics of particles in dry powder materials is an essential aspect of drug product development. The particle size distribution of either active pharmaceutical ingredients (APIs) of excipients often has a significant impact…
App Note | Technology: Scanning Electron Microscopy
The Analytical Tools Needed for Deformulation of Pharmaceutical Imaging plays an integral role in the deformulation of any product. Separation and quantification of individual ingredients often require a suite of analytical instrumentation. The Phenom ProX desktop SEM with EDS is the ideal tool for accurately…
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